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Protein

Venom allergen 5

Gene
N/A
Organism
Vespula germanica (German yellow jacket) (Paravespula germanica)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Venom allergen 5
Alternative name(s):
Allergen Ves g V
Antigen 5
Short name:
Ag5
Cysteine-rich venom protein
Short name:
CRVP
Allergen: Ves g 5
OrganismiVespula germanica (German yellow jacket) (Paravespula germanica)
Taxonomic identifieri30212 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaHymenopteraApocritaAculeataVespoideaVespidaeVespinaeVespula

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3513 Ves g 5.0101
660 Ves g 5

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002115421 – 204Venom allergen 5Add BLAST204

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi4 ↔ 17By similarity
Disulfide bondi8 ↔ 101By similarity
Disulfide bondi26 ↔ 94By similarity
Disulfide bondi170 ↔ 187By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom gland.

Structurei

3D structure databases

ProteinModelPortaliP35784
SMRiP35784
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 189SCPAdd BLAST145

Sequence similaritiesi

Belongs to the CRISP family.Curated

Family and domain databases

Gene3Di3.40.33.10, 1 hit
InterProiView protein in InterPro
IPR001283 Allrgn_V5/Tpx1
IPR018244 Allrgn_V5/Tpx1_CS
IPR014044 CAP_domain
IPR035940 CAP_sf
IPR002413 V5_allergen
PANTHERiPTHR10334 PTHR10334, 1 hit
PfamiView protein in Pfam
PF00188 CAP, 1 hit
PRINTSiPR00838 V5ALLERGEN
PR00837 V5TPXLIKE
SMARTiView protein in SMART
SM00198 SCP, 1 hit
SUPFAMiSSF55797 SSF55797, 1 hit
PROSITEiView protein in PROSITE
PS01009 CRISP_1, 1 hit
PS01010 CRISP_2, 1 hit

Sequencei

Sequence statusi: Complete.

P35784-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
NNYCKIKCLK GGVHTACKYE SLKPNCANKK VVAYGLTKQE KQDILKEHND
60 70 80 90 100
FRQKIARGLE TRGNPGPQPP AKNMKNLVWS DELAYIAQVW ANQCQYGHDT
110 120 130 140 150
CRDVAKYPVG QNVALTGSTA AKYDNPVKLV KMWEDEVKDY NPKKKFSENN
160 170 180 190 200
FLKIGHYTQM VWANTKEVGC GSIKYIQDKW HKHYLVCNYG PSGNFGNEEL

YQTK
Length:204
Mass (Da):23,330
Last modified:June 1, 1994 - v1
Checksum:iD1FB4BD21C73BC5E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti80S → N in CAJ28930 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM083317 mRNA Translation: CAJ28930.1
PIRiB44583

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM083317 mRNA Translation: CAJ28930.1
PIRiB44583

3D structure databases

ProteinModelPortaliP35784
SMRiP35784
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3513 Ves g 5.0101
660 Ves g 5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.33.10, 1 hit
InterProiView protein in InterPro
IPR001283 Allrgn_V5/Tpx1
IPR018244 Allrgn_V5/Tpx1_CS
IPR014044 CAP_domain
IPR035940 CAP_sf
IPR002413 V5_allergen
PANTHERiPTHR10334 PTHR10334, 1 hit
PfamiView protein in Pfam
PF00188 CAP, 1 hit
PRINTSiPR00838 V5ALLERGEN
PR00837 V5TPXLIKE
SMARTiView protein in SMART
SM00198 SCP, 1 hit
SUPFAMiSSF55797 SSF55797, 1 hit
PROSITEiView protein in PROSITE
PS01009 CRISP_1, 1 hit
PS01010 CRISP_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiVA5_VESGE
AccessioniPrimary (citable) accession number: P35784
Secondary accession number(s): Q3ZU96
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: October 25, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Allergens
    Nomenclature of allergens and list of entries
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