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Protein

Protein InvG

Gene

invG

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the invasion of the cells of the intestinal epithelium. Could be necessary for the export of invasion related determinants.

GO - Molecular functioni

  • identical protein binding Source: IntAct
  • protein transporter activity Source: InterPro

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport, Virulence

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-2926-MONOMER

Protein family/group databases

TCDBi1.B.22.3.2 the outer bacterial membrane secretin (secretin) family

Names & Taxonomyi

Protein namesi
Recommended name:
Protein InvG
Gene namesi
Name:invG
Ordered Locus Names:STM2898
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 14Sequence analysisAdd BLAST14
ChainiPRO_000001311115 – 562Protein InvGAdd BLAST548

Proteomic databases

PaxDbiP35672
PRIDEiP35672

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself2EBI-15771877,EBI-15771877

GO - Molecular functioni

Protein-protein interaction databases

DIPiDIP-48517N
IntActiP35672, 2 interactors
STRINGi99287.STM2898

Structurei

Secondary structure

1562
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SMRiP35672
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP35672

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP D family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105K44 Bacteria
COG1450 LUCA
HOGENOMiHOG000219449
KOiK22504
OMAiVWYDDGA
PhylomeDBiP35672

Family and domain databases

Gene3Di3.30.1370.120, 2 hits
InterProiView protein in InterPro
IPR005644 NolW-like
IPR038591 NolW-like_sf
IPR004846 T2SS/T3SS
IPR004845 T2SS_GspD_CS
IPR003522 T3SS_OM_pore_YscC
PfamiView protein in Pfam
PF00263 Secretin, 1 hit
PF03958 Secretin_N, 1 hit
PRINTSiPR01337 TYPE3OMGPROT
TIGRFAMsiTIGR02516 type_III_yscC, 1 hit
PROSITEiView protein in PROSITE
PS00875 T2SP_D, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P35672-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTHILLARV LACAALVLVT PGYSSEKIPV TGSGFVAKDD SLRTFFDAMA
60 70 80 90 100
LQLKEPVIVS KMAARKKITG NFEFHDPNAL LEKLSLQLGL IWYFDGQAIY
110 120 130 140 150
IYDASEMRNA VVSLRNVSLN EFNNFLKRSG LYNKNYPLRG DNRKGTFYVS
160 170 180 190 200
GPPVYVDMVV NAATMMDKQN DGIELGRQKI GVMRLNNTFV GDRTYNLRDQ
210 220 230 240 250
KMVIPGIATA IERLLQGEEQ PLGNIVSSEP PAMPAFSANG EKGKAANYAG
260 270 280 290 300
GMSLQEALKQ NAAAGNIKIV AYPDTNSLLV KGTAEQVHFI EMLVKALDVA
310 320 330 340 350
KRHVELSLWI VDLNKSDLER LGTSWSGSIT IGDKLGVSLN QSSISTLDGS
360 370 380 390 400
RFIAAVNALE EKKQATVVSR PVLLTQENVP AIFDNNRTFY TKLIGERNVA
410 420 430 440 450
LEHVTYGTMI RVLPRFSADG QIEMSLDIED GNDKTPQSDT TTSVDALPEV
460 470 480 490 500
GRTLISTIAR VPHGKSLLVG GYTRDANTDT VQSIPFLGKL PLIGSLFRYS
510 520 530 540 550
SKNKSNVVRV FMIEPKEIVD PLTPDASESV NNILKQSGAW SGDDKLQKWV
560
RVYLDRGQEA IK
Length:562
Mass (Da):61,766
Last modified:January 23, 2002 - v3
Checksum:i8022905BE256058D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti12A → R in AAA74040 (PubMed:7997169).Curated1
Sequence conflicti121E → Q in AAA74040 (PubMed:7997169).Curated1
Sequence conflicti197 – 205LRDQKMVIP → CAIRKWLFR in AAA74040 (PubMed:7997169).Curated9
Sequence conflicti232 – 240AMPAFSANG → RCQRFQRM in AAA74040 (PubMed:7997169).Curated9
Sequence conflicti243G → S in AAA74040 (PubMed:7997169).Curated1
Sequence conflicti262 – 264AAA → KPAEQ in AAA74040 (PubMed:7997169).Curated3
Sequence conflicti328S → T in CAA53049 (PubMed:7868245).Curated1
Sequence conflicti328S → T in AAA74040 (PubMed:7997169).Curated1
Sequence conflicti329I → V in AAA74040 (PubMed:7997169).Curated1
Sequence conflicti370 – 380RPVLLTQENVP → APGITSSGKCS in AAA74040 (PubMed:7997169).CuratedAdd BLAST11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X75302 Genomic DNA Translation: CAA53049.1
U08280 Genomic DNA Translation: AAA74040.1
AE006468 Genomic DNA Translation: AAL21778.1
PIRiS54420
RefSeqiNP_461819.1, NC_003197.2
WP_000848113.1, NC_003197.2

Genome annotation databases

EnsemblBacteriaiAAL21778; AAL21778; STM2898
GeneIDi1254421
KEGGistm:STM2898
PATRICifig|99287.12.peg.3054

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X75302 Genomic DNA Translation: CAA53049.1
U08280 Genomic DNA Translation: AAA74040.1
AE006468 Genomic DNA Translation: AAL21778.1
PIRiS54420
RefSeqiNP_461819.1, NC_003197.2
WP_000848113.1, NC_003197.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2Y9Kelectron microscopy8.30A/B/C/D/E/F/G/H/I/J/K/L/M/N/O34-170[»]
3J1Velectron microscopy-A/B/C/D/E/F/G/H/I/J/K/L/M/N/O22-178[»]
4G08X-ray1.80A22-178[»]
5TCQelectron microscopy3.60A/B/C/D/E/F/G/H/I/J/K/L/M/N/O1-562[»]
5TCRelectron microscopy6.30A/B/C/D/E/F/G/H/I/J/K/L/M/N/O1-562[»]
SMRiP35672
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48517N
IntActiP35672, 2 interactors
STRINGi99287.STM2898

Protein family/group databases

TCDBi1.B.22.3.2 the outer bacterial membrane secretin (secretin) family

Proteomic databases

PaxDbiP35672
PRIDEiP35672

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL21778; AAL21778; STM2898
GeneIDi1254421
KEGGistm:STM2898
PATRICifig|99287.12.peg.3054

Phylogenomic databases

eggNOGiENOG4105K44 Bacteria
COG1450 LUCA
HOGENOMiHOG000219449
KOiK22504
OMAiVWYDDGA
PhylomeDBiP35672

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-2926-MONOMER

Miscellaneous databases

EvolutionaryTraceiP35672

Family and domain databases

Gene3Di3.30.1370.120, 2 hits
InterProiView protein in InterPro
IPR005644 NolW-like
IPR038591 NolW-like_sf
IPR004846 T2SS/T3SS
IPR004845 T2SS_GspD_CS
IPR003522 T3SS_OM_pore_YscC
PfamiView protein in Pfam
PF00263 Secretin, 1 hit
PF03958 Secretin_N, 1 hit
PRINTSiPR01337 TYPE3OMGPROT
TIGRFAMsiTIGR02516 type_III_yscC, 1 hit
PROSITEiView protein in PROSITE
PS00875 T2SP_D, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiINVG_SALTY
AccessioniPrimary (citable) accession number: P35672
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: January 23, 2002
Last modified: November 7, 2018
This is version 118 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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