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UniProtKB - P35580 (MYH10_HUMAN)

Entry version 217 (25 May 2022)
Sequence version 3 (25 Nov 2008)
Previous versions | rss
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Protein

Myosin-10

Gene

MYH10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9.

2 Publications

Caution

Represents a conventional non-muscle myosin. This protein should not be confused with the unconventional myosin-10 (MYO10).Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi178 – 185ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding, Calmodulin-binding, Motor protein, Myosin
Biological processCell adhesion, Cell shape
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P35580

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-3928663, EPHA-mediated growth cone collapse
R-HSA-416572, Sema4D induced cell migration and growth-cone collapse
R-HSA-5625740, RHO GTPases activate PKNs
R-HSA-5625900, RHO GTPases activate CIT
R-HSA-5627117, RHO GTPases Activate ROCKs
R-HSA-5627123, RHO GTPases activate PAKs

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		P35580

SIGNOR Signaling Network Open Resource

More...SIGNORi		P35580

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Myosin-10
Alternative name(s):
Cellular myosin heavy chain, type B
Myosin heavy chain 10
Myosin heavy chain, non-muscle IIb
Non-muscle myosin heavy chain B
Short name:
NMMHC-B
Non-muscle myosin heavy chain IIb
Short name:
NMMHC II-b
Short name:
NMMHC-IIB
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MYH10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:7568, MYH10

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		160776, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P35580

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000133026

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell projection

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Associated with severe intellectual disability, microcephaly, and feeding difficulties as well as cerebral atrophy.2 Publications

Keywords - Diseasei

Disease variant

Organism-specific databases

DisGeNET

More...DisGeNETi		4628

MalaCards human disease database

More...MalaCardsi		MYH10

Open Targets

More...OpenTargetsi		ENSG00000133026

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA31366

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P35580, Tchem

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL4105746

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MYH10

Domain mapping of disease mutations (DMDM)

More...DMDMi		215274129

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001234211 – 1976Myosin-10Add BLAST1976

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei18Omega-N-methylarginineBy similarity1
Modified residuei442N6-acetyllysineCombined sources1
Modified residuei1145PhosphoserineCombined sources1
Modified residuei1241N6-acetyllysineBy similarity1
Modified residuei1301N6-acetyllysineBy similarity1
Modified residuei1645N6-acetyllysineCombined sources1
Modified residuei1930Omega-N-methylarginineBy similarity1
Modified residuei1935PhosphoserineCombined sources1
Modified residuei1937PhosphoserineCombined sources1
Modified residuei1938PhosphoserineCombined sources1
Modified residuei1939PhosphoserineCombined sources1
Modified residuei1940Omega-N-methylarginineBy similarity1
Modified residuei1952PhosphoserineCombined sources1
Modified residuei1956PhosphoserineCombined sources1
Modified residuei1960PhosphothreonineCombined sources1
Modified residuei1975PhosphoserineBy similarity1
Isoform 2 (identifier: P35580-2)
Modified residuei214PhosphoserineCombined sources1
Isoform 4 (identifier: P35580-4)
Modified residuei214PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated by ABL2.By similarity

Keywords - PTMi

Acetylation, Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P35580

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P35580

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P35580

MaxQB - The MaxQuant DataBase

More...MaxQBi		P35580

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P35580

PeptideAtlas

More...PeptideAtlasi		P35580

PRoteomics IDEntifications database

More...PRIDEi		P35580

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		28641
55095 [P35580-1]
55096 [P35580-2]
55097 [P35580-3]

PTM databases

CarbonylDB database of protein carbonylation sites

More...CarbonylDBi		P35580

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		P35580, 1 site, 2 O-linked glycans (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P35580

MetOSite database of methionine sulfoxide sites

More...MetOSitei		P35580

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P35580

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P35580

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform 1 is expressed in cerebellum and spinal chord. Isoform 2 is expressed in cerebrum and retina. Isoform 3 is expressed in the cerebrum and to a much lower extent in cerebellum.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000133026, Expressed in blood vessel layer and 251 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P35580, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P35580, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000133026, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).

Interacts with PLEKHG6 (PubMed:16721066).

Interacts with ECPAS (PubMed:20682791).

Interacts with KIF26B (By similarity).

Interacts with LARP6 (PubMed:20603131).

Interacts with MCC (PubMed:22480440).

Interacts with CFAP95 (PubMed:28345668).

By similarity5 Publications

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		110713, 226 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		P35580

Database of interacting proteins

More...DIPi		DIP-31110N

Protein interaction database and analysis system

More...IntActi		P35580, 70 interactors

Molecular INTeraction database

More...MINTi		P35580

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000353590

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		P35580

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P35580, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11976
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		P35580

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P35580

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini31 – 81Myosin N-terminal SH3-likePROSITE-ProRule annotationAdd BLAST51
Domaini85 – 783Myosin motorPROSITE-ProRule annotationAdd BLAST699
Domaini786 – 815IQPROSITE-ProRule annotationAdd BLAST30

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni661 – 683Actin-bindingPROSITE-ProRule annotationAdd BLAST23
Regioni1127 – 1147DisorderedSequence analysisAdd BLAST21
Regioni1697 – 1728DisorderedSequence analysisAdd BLAST32
Regioni1872 – 1976DisorderedSequence analysisAdd BLAST105

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili845 – 1976Sequence analysisAdd BLAST1132

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1697 – 1717Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi1872 – 1915Basic and acidic residuesSequence analysisAdd BLAST44
Compositional biasi1950 – 1965Basic and acidic residuesSequence analysisAdd BLAST16

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0160, Eukaryota
KOG0161, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155159

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000192_8_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P35580

Identification of Orthologs from Complete Genome Data

More...OMAi		XERAAAN

Database of Orthologous Groups

More...OrthoDBi		47111at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P35580

TreeFam database of animal gene trees

More...TreeFami		TF333601

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.30.30.360, 1 hit
3.40.850.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR036961, Kinesin_motor_dom_sf
IPR001609, Myosin_head_motor_dom
IPR004009, Myosin_N
IPR008989, Myosin_S1_N
IPR002928, Myosin_tail
IPR027417, P-loop_NTPase

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00612, IQ, 1 hit
PF00063, Myosin_head, 1 hit
PF02736, Myosin_N, 1 hit
PF01576, Myosin_tail_1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00193, MYOSINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00015, IQ, 1 hit
SM00242, MYSc, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50096, IQ, 1 hit
PS51456, MYOSIN_MOTOR, 1 hit
PS51844, SH3_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P35580-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAQRTGLEDP ERYLFVDRAV IYNPATQADW TAKKLVWIPS ERHGFEAASI 
        60         70         80         90        100
KEERGDEVMV ELAENGKKAM VNKDDIQKMN PPKFSKVEDM AELTCLNEAS 
       110        120        130        140        150
VLHNLKDRYY SGLIYTYSGL FCVVINPYKN LPIYSENIIE MYRGKKRHEM 
       160        170        180        190        200
PPHIYAISES AYRCMLQDRE DQSILCTGES GAGKTENTKK VIQYLAHVAS 
       210        220        230        240        250
SHKGRKDHNI PGELERQLLQ ANPILESFGN AKTVKNDNSS RFGKFIRINF 
       260        270        280        290        300
DVTGYIVGAN IETYLLEKSR AVRQAKDERT FHIFYQLLSG AGEHLKSDLL 
       310        320        330        340        350
LEGFNNYRFL SNGYIPIPGQ QDKDNFQETM EAMHIMGFSH EEILSMLKVV 
       360        370        380        390        400
SSVLQFGNIS FKKERNTDQA SMPENTVAQK LCHLLGMNVM EFTRAILTPR 
       410        420        430        440        450
IKVGRDYVQK AQTKEQADFA VEALAKATYE RLFRWLVHRI NKALDRTKRQ 
       460        470        480        490        500
GASFIGILDI AGFEIFELNS FEQLCINYTN EKLQQLFNHT MFILEQEEYQ 
       510        520        530        540        550
REGIEWNFID FGLDLQPCID LIERPANPPG VLALLDEECW FPKATDKTFV 
       560        570        580        590        600
EKLVQEQGSH SKFQKPRQLK DKADFCIIHY AGKVDYKADE WLMKNMDPLN 
       610        620        630        640        650
DNVATLLHQS SDRFVAELWK DVDRIVGLDQ VTGMTETAFG SAYKTKKGMF 
       660        670        680        690        700
RTVGQLYKES LTKLMATLRN TNPNFVRCII PNHEKRAGKL DPHLVLDQLR 
       710        720        730        740        750
CNGVLEGIRI CRQGFPNRIV FQEFRQRYEI LTPNAIPKGF MDGKQACERM 
       760        770        780        790        800
IRALELDPNL YRIGQSKIFF RAGVLAHLEE ERDLKITDII IFFQAVCRGY 
       810        820        830        840        850
LARKAFAKKQ QQLSALKVLQ RNCAAYLKLR HWQWWRVFTK VKPLLQVTRQ 
       860        870        880        890        900
EEELQAKDEE LLKVKEKQTK VEGELEEMER KHQQLLEEKN ILAEQLQAET 
       910        920        930        940        950
ELFAEAEEMR ARLAAKKQEL EEILHDLESR VEEEEERNQI LQNEKKKMQA 
       960        970        980        990       1000
HIQDLEEQLD EEEGARQKLQ LEKVTAEAKI KKMEEEILLL EDQNSKFIKE 
      1010       1020       1030       1040       1050
KKLMEDRIAE CSSQLAEEEE KAKNLAKIRN KQEVMISDLE ERLKKEEKTR 
      1060       1070       1080       1090       1100
QELEKAKRKL DGETTDLQDQ IAELQAQIDE LKLQLAKKEE ELQGALARGD 
      1110       1120       1130       1140       1150
DETLHKNNAL KVVRELQAQI AELQEDFESE KASRNKAEKQ KRDLSEELEA 
      1160       1170       1180       1190       1200
LKTELEDTLD TTAAQQELRT KREQEVAELK KALEEETKNH EAQIQDMRQR 
      1210       1220       1230       1240       1250
HATALEELSE QLEQAKRFKA NLEKNKQGLE TDNKELACEV KVLQQVKAES 
      1260       1270       1280       1290       1300
EHKRKKLDAQ VQELHAKVSE GDRLRVELAE KASKLQNELD NVSTLLEEAE 
      1310       1320       1330       1340       1350
KKGIKFAKDA ASLESQLQDT QELLQEETRQ KLNLSSRIRQ LEEEKNSLQE 
      1360       1370       1380       1390       1400
QQEEEEEARK NLEKQVLALQ SQLADTKKKV DDDLGTIESL EEAKKKLLKD 
      1410       1420       1430       1440       1450
AEALSQRLEE KALAYDKLEK TKNRLQQELD DLTVDLDHQR QVASNLEKKQ 
      1460       1470       1480       1490       1500
KKFDQLLAEE KSISARYAEE RDRAEAEARE KETKALSLAR ALEEALEAKE 
      1510       1520       1530       1540       1550
EFERQNKQLR ADMEDLMSSK DDVGKNVHEL EKSKRALEQQ VEEMRTQLEE 
      1560       1570       1580       1590       1600
LEDELQATED AKLRLEVNMQ AMKAQFERDL QTRDEQNEEK KRLLIKQVRE 
      1610       1620       1630       1640       1650
LEAELEDERK QRALAVASKK KMEIDLKDLE AQIEAANKAR DEVIKQLRKL 
      1660       1670       1680       1690       1700
QAQMKDYQRE LEEARASRDE IFAQSKESEK KLKSLEAEIL QLQEELASSE 
      1710       1720       1730       1740       1750
RARRHAEQER DELADEITNS ASGKSALLDE KRRLEARIAQ LEEELEEEQS 
      1760       1770       1780       1790       1800
NMELLNDRFR KTTLQVDTLN AELAAERSAA QKSDNARQQL ERQNKELKAK 
      1810       1820       1830       1840       1850
LQELEGAVKS KFKATISALE AKIGQLEEQL EQEAKERAAA NKLVRRTEKK 
      1860       1870       1880       1890       1900
LKEIFMQVED ERRHADQYKE QMEKANARMK QLKRQLEEAE EEATRANASR 
      1910       1920       1930       1940       1950
RKLQRELDDA TEANEGLSRE VSTLKNRLRR GGPISFSSSR SGRRQLHLEG 
      1960       1970 
ASLELSDDDT ESKTSDVNET QPPQSE
Length:1,976
Mass (Da):228,999
Last modified:November 25, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA7C91944EBC2368F
GO
Isoform 2 (identifier: P35580-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     211-211: P → PQESPKPVKHQSGSLLY

Show »
Length:1,992
Mass (Da):230,779
Checksum:i2FCF86A36AB04BC5
GO
Isoform 3 (identifier: P35580-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     621-621: D → DEIQNIQRASFYDSVSGLHEPP

Show »
Length:1,997
Mass (Da):231,369
Checksum:i59FCA83F827E415E
GO
Isoform 4 (identifier: P35580-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     211-211: P → PQESPKPVKHQ
     621-621: D → DEIQNIQRASFYDSVSGLHEPP

Show »
Length:2,007
Mass (Da):232,528
Checksum:iD56BDA1A873045A2
GO
Isoform 5 (identifier: P35580-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     211-211: P → PESPKPVKHQ

Show »
Length:1,985
Mass (Da):230,030
Checksum:i493EC32CF0F26E58
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A8I5KSC2A0A8I5KSC2_HUMAN
Myosin-10
MYH10
199Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A8I5KTT7A0A8I5KTT7_HUMAN
Myosin-10
MYH10
207Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A8I5KZ38A0A8I5KZ38_HUMAN
Myosin-10
MYH10
1,986Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAE06108 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti800Y → C in AAA99177 (PubMed:7499478).Curated1
Sequence conflicti943 – 944NE → KK in AAH08968 (Ref. 5) Curated2
Sequence conflicti1429L → P in AAI17691 (Ref. 5) Curated1
Sequence conflicti1751N → D in AAB28952 (PubMed:7916668).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_078649270R → C Probable disease-associated variant found in a patient with severe intellectual disease, microcephaly and feeding difficulties as well as cerebral atrophy. 1 PublicationCorresponds to variant dbSNP:rs727504231Ensembl.1
Natural variantiVAR_078650908 – 1976Missing Probable disease-associated variant found in a patient with intrauterine growth restriction, microcephaly, developmental delay, failure to thrive, congenital bilateral hip dysplasia, cerebral and cerebellar atrophy, hydrocephalus and congenital diaphragmatic hernia. 1 PublicationAdd BLAST1069

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_022013211P → PQESPKPVKHQSGSLLY in isoform 2. 1 Publication1
Alternative sequenceiVSP_046033211P → PQESPKPVKHQ in isoform 4. 1 Publication1
Alternative sequenceiVSP_054974211P → PESPKPVKHQ in isoform 5. 1 Publication1
Alternative sequenceiVSP_022014621D → DEIQNIQRASFYDSVSGLHE PP in isoform 3 and isoform 4. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
M69181 mRNA Translation: AAA99177.1
AB210026 mRNA Translation: BAE06108.1 Different initiation.
AC011061 Genomic DNA No translation available.
AC025518 Genomic DNA No translation available.
AC026130 Genomic DNA No translation available.
CH471108 Genomic DNA Translation: EAW90046.1
CH471108 Genomic DNA Translation: EAW90047.1
CH471108 Genomic DNA Translation: EAW90048.1
CH471108 Genomic DNA Translation: EAW90049.1
BC000280 mRNA Translation: AAH00280.1
BC008968 mRNA Translation: AAH08968.1
BC117690 mRNA Translation: AAI17691.1
BC117691 mRNA Translation: AAI17692.1
BC144668 mRNA Translation: AAI44669.1
BC150634 mRNA Translation: AAI50635.1
U15618 mRNA Translation: AAA87712.1
S67247 mRNA Translation: AAB28952.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS11144.1 [P35580-1]
CCDS58515.1 [P35580-4]
CCDS73984.1 [P35580-5]

Protein sequence database of the Protein Information Resource

More...PIRi		A59252
I65769

NCBI Reference Sequences

More...RefSeqi		NP_001242941.1, NM_001256012.1 [P35580-4]
NP_001243024.1, NM_001256095.1 [P35580-5]
NP_005955.3, NM_005964.3 [P35580-1]
XP_016880169.1, XM_017024680.1 [P35580-5]
XP_016880170.1, XM_017024681.1 [P35580-1]
XP_016880171.1, XM_017024682.1 [P35580-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000269243.8; ENSP00000269243.4; ENSG00000133026.14
ENST00000360416.8; ENSP00000353590.4; ENSG00000133026.14 [P35580-4]
ENST00000379980.8; ENSP00000369315.5; ENSG00000133026.14 [P35580-5]
ENST00000686654.1; ENSP00000508862.1; ENSG00000133026.14 [P35580-4]
ENST00000687178.1; ENSP00000509748.1; ENSG00000133026.14 [P35580-5]
ENST00000688902.1; ENSP00000509091.1; ENSG00000133026.14 [P35580-4]
ENST00000693441.1; ENSP00000509241.1; ENSG00000133026.14 [P35580-4]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		4628

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:4628

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000360416.8; ENSP00000353590.4; NM_001256012.3; NP_001242941.1 [P35580-4]

UCSC genome browser

More...UCSCi		uc002gll.5, human [P35580-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M69181 mRNA Translation: AAA99177.1
AB210026 mRNA Translation: BAE06108.1 Different initiation.
AC011061 Genomic DNA No translation available.
AC025518 Genomic DNA No translation available.
AC026130 Genomic DNA No translation available.
CH471108 Genomic DNA Translation: EAW90046.1
CH471108 Genomic DNA Translation: EAW90047.1
CH471108 Genomic DNA Translation: EAW90048.1
CH471108 Genomic DNA Translation: EAW90049.1
BC000280 mRNA Translation: AAH00280.1
BC008968 mRNA Translation: AAH08968.1
BC117690 mRNA Translation: AAI17691.1
BC117691 mRNA Translation: AAI17692.1
BC144668 mRNA Translation: AAI44669.1
BC150634 mRNA Translation: AAI50635.1
U15618 mRNA Translation: AAA87712.1
S67247 mRNA Translation: AAB28952.1
CCDSiCCDS11144.1 [P35580-1]
CCDS58515.1 [P35580-4]
CCDS73984.1 [P35580-5]
PIRiA59252
I65769
RefSeqiNP_001242941.1, NM_001256012.1 [P35580-4]
NP_001243024.1, NM_001256095.1 [P35580-5]
NP_005955.3, NM_005964.3 [P35580-1]
XP_016880169.1, XM_017024680.1 [P35580-5]
XP_016880170.1, XM_017024681.1 [P35580-1]
XP_016880171.1, XM_017024682.1 [P35580-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4PD3X-ray2.84A/B1-782[»]
AlphaFoldDBiP35580
SMRiP35580
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi110713, 226 interactors
CORUMiP35580
DIPiDIP-31110N
IntActiP35580, 70 interactors
MINTiP35580
STRINGi9606.ENSP00000353590

Chemistry databases

BindingDBiP35580
ChEMBLiCHEMBL4105746

PTM databases

CarbonylDBiP35580
GlyGeniP35580, 1 site, 2 O-linked glycans (1 site)
iPTMnetiP35580
MetOSiteiP35580
PhosphoSitePlusiP35580
SwissPalmiP35580

Genetic variation databases

BioMutaiMYH10
DMDMi215274129

Proteomic databases

EPDiP35580
jPOSTiP35580
MassIVEiP35580
MaxQBiP35580
PaxDbiP35580
PeptideAtlasiP35580
PRIDEiP35580
ProteomicsDBi28641
55095 [P35580-1]
55096 [P35580-2]
55097 [P35580-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		24686, 163 antibodies from 31 providers

The DNASU plasmid repository

More...DNASUi		4628

Genome annotation databases

EnsembliENST00000269243.8; ENSP00000269243.4; ENSG00000133026.14
ENST00000360416.8; ENSP00000353590.4; ENSG00000133026.14 [P35580-4]
ENST00000379980.8; ENSP00000369315.5; ENSG00000133026.14 [P35580-5]
ENST00000686654.1; ENSP00000508862.1; ENSG00000133026.14 [P35580-4]
ENST00000687178.1; ENSP00000509748.1; ENSG00000133026.14 [P35580-5]
ENST00000688902.1; ENSP00000509091.1; ENSG00000133026.14 [P35580-4]
ENST00000693441.1; ENSP00000509241.1; ENSG00000133026.14 [P35580-4]
GeneIDi4628
KEGGihsa:4628
MANE-SelectiENST00000360416.8; ENSP00000353590.4; NM_001256012.3; NP_001242941.1 [P35580-4]
UCSCiuc002gll.5, human [P35580-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		4628
DisGeNETi4628

GeneCards: human genes, protein and diseases

More...GeneCardsi		MYH10
HGNCiHGNC:7568, MYH10
HPAiENSG00000133026, Low tissue specificity
MalaCardsiMYH10
MIMi160776, gene
neXtProtiNX_P35580
OpenTargetsiENSG00000133026
PharmGKBiPA31366
VEuPathDBiHostDB:ENSG00000133026

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0160, Eukaryota
KOG0161, Eukaryota
GeneTreeiENSGT00940000155159
HOGENOMiCLU_000192_8_0_1
InParanoidiP35580
OMAiXERAAAN
OrthoDBi47111at2759
PhylomeDBiP35580
TreeFamiTF333601

Enzyme and pathway databases

PathwayCommonsiP35580
ReactomeiR-HSA-3928663, EPHA-mediated growth cone collapse
R-HSA-416572, Sema4D induced cell migration and growth-cone collapse
R-HSA-5625740, RHO GTPases activate PKNs
R-HSA-5625900, RHO GTPases activate CIT
R-HSA-5627117, RHO GTPases Activate ROCKs
R-HSA-5627123, RHO GTPases activate PAKs
SignaLinkiP35580
SIGNORiP35580

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		4628, 19 hits in 1086 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		MYH10, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		MYH10

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		4628
PharosiP35580, Tchem

Protein Ontology

More...PROi		PR:P35580
RNActiP35580, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000133026, Expressed in blood vessel layer and 251 other tissues
ExpressionAtlasiP35580, baseline and differential
GenevisibleiP35580, HS

Family and domain databases

Gene3Di2.30.30.360, 1 hit
3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR036961, Kinesin_motor_dom_sf
IPR001609, Myosin_head_motor_dom
IPR004009, Myosin_N
IPR008989, Myosin_S1_N
IPR002928, Myosin_tail
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00612, IQ, 1 hit
PF00063, Myosin_head, 1 hit
PF02736, Myosin_N, 1 hit
PF01576, Myosin_tail_1, 1 hit
PRINTSiPR00193, MYOSINHEAVY
SMARTiView protein in SMART
SM00015, IQ, 1 hit
SM00242, MYSc, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096, IQ, 1 hit
PS51456, MYOSIN_MOTOR, 1 hit
PS51844, SH3_LIKE, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMYH10_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P35580
Secondary accession number(s): B2RWP9
, D3DTS1, F8VTL3, Q12989, Q149N3, Q149N4, Q16087, Q4LE45, Q6PK16, Q9BWG0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: November 25, 2008
Last modified: May 25, 2022
This is version 217 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families
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