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Protein

Chaperonin CPN60, mitochondrial

Gene
N/A
Organism
Brassica napus (Rape)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperonin CPN60, mitochondrial
OrganismiBrassica napus (Rape)
Taxonomic identifieri3708 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 32MitochondrionSequence analysisAdd BLAST32
ChainiPRO_000000501033 – 587Chaperonin CPN60, mitochondrialAdd BLAST555

Proteomic databases

PRIDEiP35480

Structurei

3D structure databases

ProteinModelPortaliP35480
SMRiP35480
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

KOiK04077

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
HAMAPiMF_00600 CH60, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P35480-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYRLISSIAS KARVARNCTS QIGSRLSSTR NYAAKDIRFG VEGRALMLRG
60 70 80 90 100
VEELADAVKV TIPPKGRNVI IEQSWGAPKV TKDGVTVAKS IEFKDRVKNV
110 120 130 140 150
GASLVKQVAN RPTQLNRCLG DGTTCATVLT RAIFTEGCKS VAAGMNAMDL
160 170 180 190 200
RRGIKLAVDT VVTKLKSRAR MISTSEEIAQ VGTISANGDR ELVTDCKAME
210 220 230 240 250
SVGKEGVITI QDGKTLFNEL EVVEGMKIDR GYISPYFITN QKNQKCELED
260 270 280 290 300
PLILIHEKKI SNLNSMVKVL ELALKSQRSL LIVAADLESD ALAVLILNKL
310 320 330 340 350
RAGIKVCAVK APGFGENRKA NMHDLATLTG AQVITEELGM NLEKIDLSML
360 370 380 390 400
GNCKKITVSK DDTVFLGWGA GDKKAIGERC EQIRSMVEAS ESDYDKEKLQ
410 420 430 440 450
ERLAKLSGGV AVLKIGGASE SEVGEKKDRV TDALNATKAA VEEGIVPGGG
460 470 480 490 500
VALLYASKEL DKLSTANFDH KIGVQIIQNA LKTPVYTIAS NAGVEGAVIV
510 520 530 540 550
GKLLESDNPD LGYDAAKGEY VDMVKSGIID PVKVIRTALV DAASVSSLLT
560 570 580
TTEAVVTEIP TKEDASPAMG GGGGGMGGMG GMGGMGF
Length:587
Mass (Da):62,355
Last modified:June 1, 1994 - v1
Checksum:i09AAC1691E31E097
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z27165 mRNA Translation: CAA81689.1
PIRiS38634
RefSeqiNP_001302985.1, NM_001316056.1

Genome annotation databases

GeneIDi106437789
KEGGibna:106437789

Similar proteinsi

Entry informationi

Entry nameiCH60_BRANA
AccessioniPrimary (citable) accession number: P35480
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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