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Protein

Urokinase plasminogen activator surface receptor

Gene

Plaur

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-162791 Attachment of GPI anchor to uPAR
R-MMU-6798695 Neutrophil degranulation
R-MMU-75205 Dissolution of Fibrin Clot

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Urokinase plasminogen activator surface receptor
Short name:
U-PAR
Short name:
uPAR
Alternative name(s):
CD_antigen: CD87
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Plaur
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:97612 Plaur

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003609624 – ?298Urokinase plasminogen activator surface receptorAdd BLAST275
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_0000036097?299 – 327Removed in mature formSequence analysisAdd BLAST29

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi26 ↔ 471 Publication
Disulfide bondi29 ↔ 351 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi32N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi40 ↔ 681 Publication
Glycosylationi75N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi94 ↔ 991 Publication
Disulfide bondi119 ↔ 1461 Publication
Disulfide bondi122 ↔ 1291 Publication
Disulfide bondi139 ↔ 1681 Publication
Disulfide bondi174 ↔ 1911 Publication
Glycosylationi183N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi192 ↔ 1971 Publication
Glycosylationi193N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi215 ↔ 2431 Publication
Disulfide bondi218 ↔ 2261 Publication
Glycosylationi221N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi236 ↔ 2621 Publication
Glycosylationi254N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi268 ↔ 2871 Publication
Glycosylationi282N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi288 ↔ 2931 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi298GPI-anchor amidated glycineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P35456

PeptideAtlas

More...
PeptideAtlasi
P35456

PRoteomics IDEntifications database

More...
PRIDEi
P35456

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P35456

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P35456

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P35456

Miscellaneous databases

CutDB - Proteolytic event database

More...
PMAP-CutDBi
P35456

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in angiogenic endothelial cells (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000046223 Expressed in 142 organ(s), highest expression level in embryo

CleanEx database of gene expression profiles

More...
CleanExi
MM_PLAUR

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P35456 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P35456 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer (Probable). Interacts (via the UPAR/Ly6 domains) with SRPX2. Interacts with MRC2 (By similarity). Interacts with SORL1 (By similarity).By similarityCurated

GO - Molecular functioni

Protein-protein interaction databases

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-510 uPA-uPAR complex
CPX-526 uPA-uPAR-vitronectin complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P35456

Protein interaction database and analysis system

More...
IntActi
P35456, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000002284

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1327
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P35456

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P35456

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P35456

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini24 – 117UPAR/Ly6 1Add BLAST94
Domaini117 – 212UPAR/Ly6 2Add BLAST96
Domaini213 – 298UPAR/Ly6 3Add BLAST86

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJ50 Eukaryota
ENOG410Z47S LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153599

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000136855

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG000245

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P35456

KEGG Orthology (KO)

More...
KOi
K03985

Identification of Orthologs from Complete Genome Data

More...
OMAi
EVVERGC

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0FQ6

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P35456

TreeFam database of animal gene trees

More...
TreeFami
TF338662

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018363 CD59_antigen_CS
IPR016054 LY6_UPA_recep-like
IPR033084 U-PAR

The PANTHER Classification System

More...
PANTHERi
PTHR10624:SF6 PTHR10624:SF6, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00021 UPAR_LY6, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00134 LU, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00983 LY6_UPAR, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P35456-1) [UniParc]FASTAAdd to basket
Also known as: GPI-anchored

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGLPRRLLLL LLLATTCVPA SQGLQCMQCE SNQSCLVEEC ALGQDLCRTT
60 70 80 90 100
VLREWQDDRE LEVVTRGCAH SEKTNRTMSY RMGSMIISLT ETVCATNLCN
110 120 130 140 150
RPRPGARGRA FPQGRYLECA SCTSLDQSCE RGREQSLQCR YPTEHCIEVV
160 170 180 190 200
TLQSTERSLK DEDYTRGCGS LPGCPGTAGF HSNQTFHFLK CCNYTHCNGG
210 220 230 240 250
PVLDLQSFPP NGFQCYSCEG NNTLGCSSEE ASLINCRGPM NQCLVATGLD
260 270 280 290 300
VLGNRSYTVR GCATASWCQG SHVADSFPTH LNVSVSCCHG SGCNSPTGGA
310 320
PRPGPAQLSL IASLLLTLGL WGVLLWT
Note: GPI-anchored form.
Length:327
Mass (Da):35,428
Last modified:June 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA117441D738B6343
GO
Isoform 2 (identifier: P35456-2) [UniParc] [UniParc]FASTAAdd to basket
Also known as: Secreted

The sequence of this isoform differs from the canonical sequence as follows:
     157-222: RSLKDEDYTR...FQCYSCEGNN → SKLPSAGQLL...LVMSRILLSF
     223-327: Missing.

Show »
Length:222
Mass (Da):24,619
Checksum:i8BA6B9F21389C587
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0U1RNN0A0A0U1RNN0_MOUSE
Plasminogen activator, urokinase re...
Plaur mCG_7264
222Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0U1RNF3A0A0U1RNF3_MOUSE
Urokinase plasminogen activator sur...
Plaur
74Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_031837157 – 222RSLKD…CEGNN → SKLPSAGQLLVEIFKSWEQS ASKRQLNPHTVTGPTFSVTG SSGSLDQLGSDQEPSYLVMS RILLSF in isoform 2. 1 PublicationAdd BLAST66
Alternative sequenceiVSP_031838223 – 327Missing in isoform 2. 1 PublicationAdd BLAST105

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X62700 mRNA Translation: CAA44574.1
X62701 mRNA Translation: CAA44575.1
U12235 Genomic DNA Translation: AAB60484.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS20950.1 [P35456-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
A55356
B41643

NCBI Reference Sequences

More...
RefSeqi
NP_035243.1, NM_011113.4 [P35456-1]
XP_006539702.1, XM_006539639.3 [P35456-1]
XP_006539703.1, XM_006539640.3 [P35456-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.1359

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000002284; ENSMUSP00000002284; ENSMUSG00000046223 [P35456-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
18793

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:18793

UCSC genome browser

More...
UCSCi
uc009fpr.1 mouse [P35456-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X62700 mRNA Translation: CAA44574.1
X62701 mRNA Translation: CAA44575.1
U12235 Genomic DNA Translation: AAB60484.1
CCDSiCCDS20950.1 [P35456-1]
PIRiA55356
B41643
RefSeqiNP_035243.1, NM_011113.4 [P35456-1]
XP_006539702.1, XM_006539639.3 [P35456-1]
XP_006539703.1, XM_006539640.3 [P35456-1]
UniGeneiMm.1359

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3LAQX-ray3.20U/V24-300[»]
ProteinModelPortaliP35456
SMRiP35456
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-510 uPA-uPAR complex
CPX-526 uPA-uPAR-vitronectin complex
CORUMiP35456
IntActiP35456, 1 interactor
STRINGi10090.ENSMUSP00000002284

PTM databases

iPTMnetiP35456
PhosphoSitePlusiP35456
SwissPalmiP35456

Proteomic databases

PaxDbiP35456
PeptideAtlasiP35456
PRIDEiP35456

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
18793
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000002284; ENSMUSP00000002284; ENSMUSG00000046223 [P35456-1]
GeneIDi18793
KEGGimmu:18793
UCSCiuc009fpr.1 mouse [P35456-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5329
MGIiMGI:97612 Plaur

Phylogenomic databases

eggNOGiENOG410IJ50 Eukaryota
ENOG410Z47S LUCA
GeneTreeiENSGT00940000153599
HOGENOMiHOG000136855
HOVERGENiHBG000245
InParanoidiP35456
KOiK03985
OMAiEVVERGC
OrthoDBiEOG091G0FQ6
PhylomeDBiP35456
TreeFamiTF338662

Enzyme and pathway databases

ReactomeiR-MMU-162791 Attachment of GPI anchor to uPAR
R-MMU-6798695 Neutrophil degranulation
R-MMU-75205 Dissolution of Fibrin Clot

Miscellaneous databases

EvolutionaryTraceiP35456
PMAP-CutDBiP35456

Protein Ontology

More...
PROi
PR:P35456

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000046223 Expressed in 142 organ(s), highest expression level in embryo
CleanExiMM_PLAUR
ExpressionAtlasiP35456 baseline and differential
GenevisibleiP35456 MM

Family and domain databases

InterProiView protein in InterPro
IPR018363 CD59_antigen_CS
IPR016054 LY6_UPA_recep-like
IPR033084 U-PAR
PANTHERiPTHR10624:SF6 PTHR10624:SF6, 1 hit
PfamiView protein in Pfam
PF00021 UPAR_LY6, 3 hits
SMARTiView protein in SMART
SM00134 LU, 3 hits
PROSITEiView protein in PROSITE
PS00983 LY6_UPAR, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUPAR_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P35456
Secondary accession number(s): P35457
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: December 5, 2018
This is version 145 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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