Fshr

Functionⁱ

G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.By similarity

GO - Molecular functionⁱ

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

activation of adenylate cyclase activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: MGI
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Source: MGI
Inferred from direct assayⁱ
- 16630814
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Source: MGI
Inferred from direct assayⁱ
- 10330114
basement membrane organization
Source: MGI
Inferred from mutant phenotypeⁱ
- 9811848
cellular response to follicle-stimulating hormone stimulus Source: UniProtKB
cellular water homeostasis
Source: MGI
Inferred from mutant phenotypeⁱ
- 14998910
follicle-stimulating hormone signaling pathway
Source: MGI
Inferred from direct assayⁱ
- 10330114
G protein-coupled receptor signaling pathway Source: MGI
hormone-mediated signaling pathway
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
locomotory behavior
Source: MGI
Inferred from mutant phenotypeⁱ
- 14502087
negative regulation of bone resorption
Source: MGI
Inferred from mutant phenotypeⁱ
- 11089565
- 17332067
neuron projection development
Source: MGI
Inferred from mutant phenotypeⁱ
- 12204217
ovarian follicle development
Source: MGI
Inferred from mutant phenotypeⁱ
ovulation cycle process
Source: MGI
Inferred from mutant phenotypeⁱ
- 11089565
phospholipase C-activating G protein-coupled receptor signaling pathway
Source: MGI
Inferred from direct assayⁱ
- 10330114
positive regulation of adenylate cyclase activity Source: UniProtKB
positive regulation of ERK1 and ERK2 cascade Source: UniProtKB
positive regulation of intracellular estrogen receptor signaling pathway
Source: MGI
Inferred from mutant phenotypeⁱ
- 11089565
positive regulation of phosphatidylinositol 3-kinase signaling Source: UniProtKB
primary ovarian follicle growth
Source: MGI
Inferred from mutant phenotypeⁱ
- 12801993
regulation of acetylcholine metabolic process
Source: MGI
Inferred from genetic interactionⁱ
- 12204217
regulation of chromosome organization
Source: MGI
Inferred from mutant phenotypeⁱ
- 14680821
regulation of hormone metabolic process
Source: MGI
Inferred from mutant phenotypeⁱ
regulation of intracellular estrogen receptor signaling pathway
Source: MGI
Inferred from mutant phenotypeⁱ
- 18063689
- 18676690
regulation of MAPK cascade
Source: MGI
Inferred from mutant phenotypeⁱ
- 12204217
regulation of osteoclast differentiation
Source: MGI
Inferred from mutant phenotypeⁱ
- 16630814
regulation of platelet-derived growth factor receptor signaling pathway
Source: MGI
Inferred from mutant phenotypeⁱ
- 16344272
regulation of protein kinase A signaling Source: UniProtKB
regulation of protein phosphorylation
Source: MGI
Inferred from mutant phenotypeⁱ
- 12204217
regulation of systemic arterial blood pressure
Source: MGI
Inferred from mutant phenotypeⁱ
- 18599597
Sertoli cell development
Source: MGI
Inferred from mutant phenotypeⁱ
- 14998910
Sertoli cell proliferation
Source: MGI
Inferred from mutant phenotypeⁱ
- 11466221
- 18403489
spermatid development
Source: MGI
Inferred from mutant phenotypeⁱ
- 11466221
- 15973687
spermatogenesis
Source: MGI
Inferred from mutant phenotypeⁱ
spermatogenesis, exchange of chromosomal proteins
Source: MGI
Inferred from mutant phenotypeⁱ
- 14680821
sperm chromatin condensation
Source: MGI
Inferred from mutant phenotypeⁱ
- 10775161
transcytosis Source: MGI
uterus development
Source: MGI
Inferred from mutant phenotypeⁱ
- 10803590

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptor, Receptor, Transducer

Molecular function

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactomeⁱ	R-MMU-375281 Hormone ligand-binding receptors R-MMU-418555 G alpha (s) signalling events

Reactomeⁱ

R-MMU-375281 Hormone ligand-binding receptors
R-MMU-418555 G alpha (s) signalling events

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Follicle-stimulating hormone receptor Short name: FSH-R Alternative name(s): Follitropin receptor
Gene namesⁱ	Name:Fshr
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 17

Organism-specific databases

MGIⁱ	MGI:95583 Fshr

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	18 – 365	ExtracellularSequence analysisAdd BLAST	348
Transmembraneⁱ	366 – 386	Helical; Name=1Sequence analysisAdd BLAST	21
Topological domainⁱ	387 – 397	CytoplasmicSequence analysisAdd BLAST	11
Transmembraneⁱ	398 – 420	Helical; Name=2Sequence analysisAdd BLAST	23
Topological domainⁱ	421 – 442	ExtracellularSequence analysisAdd BLAST	22
Transmembraneⁱ	443 – 464	Helical; Name=3Sequence analysisAdd BLAST	22
Topological domainⁱ	465 – 484	CytoplasmicSequence analysisAdd BLAST	20
Transmembraneⁱ	485 – 507	Helical; Name=4Sequence analysisAdd BLAST	23
Topological domainⁱ	508 – 527	ExtracellularSequence analysisAdd BLAST	20
Transmembraneⁱ	528 – 549	Helical; Name=5Sequence analysisAdd BLAST	22
Topological domainⁱ	550 – 572	CytoplasmicSequence analysisAdd BLAST	23
Transmembraneⁱ	573 – 596	Helical; Name=6Sequence analysisAdd BLAST	24
Topological domainⁱ	597 – 607	ExtracellularSequence analysisAdd BLAST	11
Transmembraneⁱ	608 – 629	Helical; Name=7Sequence analysisAdd BLAST	22
Topological domainⁱ	630 – 692	CytoplasmicSequence analysisAdd BLAST	63

Keywords - Cellular componentⁱ

Cell membrane, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 17	Sequence analysisAdd BLAST		17
ChainⁱPRO_0000012773	18 – 692	Follicle-stimulating hormone receptorAdd BLAST		675

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Disulfide bondⁱ	18 ↔ 25	PROSITE-ProRule annotation
Disulfide bondⁱ	23 ↔ 32	PROSITE-ProRule annotation
Glycosylationⁱ	191	N-linked (GlcNAc...) asparagineBy similarity	1
Glycosylationⁱ	199	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	275 ↔ 345	By similarity
Disulfide bondⁱ	276 ↔ 355	By similarity
Disulfide bondⁱ	276 ↔ 292	By similarity
Disulfide bondⁱ	292 ↔ 337	By similarity
Glycosylationⁱ	293	N-linked (GlcNAc...) asparagineBy similarity	1
Modified residueⁱ	334	SulfotyrosineBy similarity	1
Disulfide bondⁱ	441 ↔ 516	PROSITE-ProRule annotation

Post-translational modificationⁱ

N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone.By similarity

Sulfated.By similarity

Keywords - PTMⁱ

Disulfide bond, Glycoprotein, Sulfation

Proteomic databases

PaxDbⁱ	P35378
PRIDEⁱ	P35378

PTM databases

PhosphoSitePlusⁱ	P35378

PhosphoSitePlusⁱ

P35378

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000032937 Expressed in 24 organ(s), highest expression level in cumulus cell
CleanExⁱ	MM_FSHR
ExpressionAtlasⁱ	P35378 baseline and differential
Genevisibleⁱ	P35378 MM

Interactionⁱ

Subunit structureⁱ

Homotrimer. Functions as a homotrimer binding the FSH hormone heterodimer composed of CGA and FSHB (By similarity). Interacts with ARRB2 (By similarity).By similarity

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000040477

STRINGⁱ

10090.ENSMUSP00000040477

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P35378
SMRⁱ	P35378
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	18 – 46	LRRNTAdd BLAST	29
Repeatⁱ	49 – 72	LRR 1Add BLAST	24
Repeatⁱ	73 – 97	LRR 2Add BLAST	25
Repeatⁱ	98 – 118	LRR 3Add BLAST	21
Repeatⁱ	119 – 143	LRR 4Add BLAST	25
Repeatⁱ	144 – 169	LRR 5Add BLAST	26
Repeatⁱ	170 – 192	LRR 6Add BLAST	23
Repeatⁱ	193 – 216	LRR 7Add BLAST	24
Repeatⁱ	217 – 240	LRR 8Add BLAST	24
Repeatⁱ	241 – 259	LRR 9Add BLAST	19

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.PROSITE-ProRule annotation

Keywords - Domainⁱ

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG2087 Eukaryota ENOG410XR1T LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119088
HOGENOMⁱ	HOG000045902
HOVERGENⁱ	HBG003521
InParanoidⁱ	P35378
KEGG Orthology (KO) More...KOⁱ	K04247
OMAⁱ	FGCYEMQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02BV
PhylomeDBⁱ	P35378
TreeFamⁱ	TF316814

Family and domain databases

InterProⁱ	View protein in InterPro IPR002272 FSH_rcpt IPR024635 GnHR_TM IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR002131 Gphrmn_rcpt_fam IPR026906 LRR_5 IPR000372 LRRNT IPR034298 TSHR/LHCGR/FSHR
PANTHERⁱ	PTHR24372 PTHR24372, 1 hit PTHR24372:SF5 PTHR24372:SF5, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit PF12369 GnHR_trans, 1 hit PF13306 LRR_5, 2 hits PF01462 LRRNT, 1 hit
PRINTSⁱ	PR01143 FSHRECEPTOR PR00373 GLYCHORMONER PR00237 GPCRRHODOPSN
SMARTⁱ	View protein in SMART SM00013 LRRNT, 1 hit
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P35378-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MALLLVSLLA FLGSGSGCHH WLCHCSNRVF LCQDSKVTEI PPDLPRNAIE 
        60         70         80         90        100
LRFVLTKLRV IPKGSFSGFG DLEKIEISQN DVLEVIEADV FSNLPNLHEI 
       110        120        130        140        150
RIEKANNLLY INPEAFQNLP SLRYLLISNT GIKHLPAFHK IQSLQKVLLD 
       160        170        180        190        200
IQDNINIHII ARNSFMGLSF ESVILWLNKN GIQEIHNCAF NGTQLDELNL 
       210        220        230        240        250
SDNNNLEELP DDVFQGASGP VVLDISRTKV YSLPNHGLEN LKKLRARSTY 
       260        270        280        290        300
RLKKLPSLDK FVMLIEASLT YPSHCCAFAN WRRQTSELHP ICNKSISRQD 
       310        320        330        340        350
IDDMTQPGDQ RVSLVDDEPS YGKGSDMLYS EFDYDLCNEF VDVTCSPKPD 
       360        370        380        390        400
AFNPCEDIMG YNILRVLIWF ISILAITGNT TVLVVLTTSQ YKLTVPRFLM 
       410        420        430        440        450
CNLAFADLCI GIYLLLIASV DIHTKSQYHN YAIDWQTGAG CDAAGFFTVF 
       460        470        480        490        500
ASELSVYTLA AITLERWHTI THAMQLECKV QLCHAASIMV LGWAFAFAAA 
       510        520        530        540        550
LFPIFGISSY MKVSICLPMD IDSPLSQLYV MALLVLNALA FVVICGCYTH 
       560        570        580        590        600
IYLTVRNPNI VSSSRDTKIA KRMATLIFTD FLCMAPILFF AISASLKVPL 
       610        620        630        640        650
ITVSKAKILL VLFYPINSCA NPFLYAIFTK NFRRDFFVLM SKFGCYEVQA 
       660        670        680        690 
QIYKTETSSI THNFHSRKNP CSSAPRVTNS YVLVPLNHSV QN

Length:692

Mass (Da):77,769

Last modified:September 26, 2001 - v2

Checksum:ⁱ4B57229180563A44

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	436	Q → K in BAB30351 (PubMed:16141072).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF095642 mRNA Translation: AAC67559.1 AK016635 mRNA Translation: BAB30351.1 S49632 Genomic DNA Translation: AAB24401.1 M87570 Genomic DNA Translation: AAA37641.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS29026.1
PIRⁱ	I57670
NCBI Reference Sequences More...RefSeqⁱ	NP_038551.3, NM_013523.3
UniGeneⁱ	Mm.57155

Genome annotation databases

Ensemblⁱ	ENSMUST00000035701; ENSMUSP00000040477; ENSMUSG00000032937
GeneIDⁱ	14309
KEGGⁱ	mmu:14309
UCSC genome browser More...UCSCⁱ	uc008dvx.1 mouse

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P35378	Follicle-stimulating hormone receptor		MOUSE		692	UniRef100_P35378

Protein	Similar proteins		Species	Score	Length	Source
P35378	Follicle-stimulating hormone receptor		MOUSE		692	UniRef90_P35378

Protein	Similar proteins		Species	Score	Length	Source
P35378	Lutropin-choriogonadotropic hormone receptor		RAT		700	UniRef50_P16235
Lutropin-choriogonadotropic hormone receptor		CALJA		676
Lutropin-choriogonadotropic hormone receptor (Fragment)		SHEEP		538
Follicle-stimulating hormone receptor		CAVPO		695
Follicle-stimulating hormone receptor		FELCA		695
+527

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF095642 mRNA Translation: AAC67559.1 AK016635 mRNA Translation: BAB30351.1 S49632 Genomic DNA Translation: AAB24401.1 M87570 Genomic DNA Translation: AAA37641.1
CCDSⁱ	CCDS29026.1
PIRⁱ	I57670
RefSeqⁱ	NP_038551.3, NM_013523.3
UniGeneⁱ	Mm.57155

3D structure databases

ProteinModelPortalⁱ	P35378
SMRⁱ	P35378
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000040477

STRINGⁱ

10090.ENSMUSP00000040477

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

PTM databases

PhosphoSitePlusⁱ	P35378

PhosphoSitePlusⁱ

P35378

Proteomic databases

PaxDbⁱ	P35378
PRIDEⁱ	P35378

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000035701; ENSMUSP00000040477; ENSMUSG00000032937
GeneIDⁱ	14309
KEGGⁱ	mmu:14309
UCSCⁱ	uc008dvx.1 mouse

Organism-specific databases

CTDⁱ	2492
MGIⁱ	MGI:95583 Fshr

Phylogenomic databases

eggNOGⁱ	KOG2087 Eukaryota ENOG410XR1T LUCA
GeneTreeⁱ	ENSGT00760000119088
HOGENOMⁱ	HOG000045902
HOVERGENⁱ	HBG003521
InParanoidⁱ	P35378
KOⁱ	K04247
OMAⁱ	FGCYEMQ
OrthoDBⁱ	EOG091G02BV
PhylomeDBⁱ	P35378
TreeFamⁱ	TF316814

Enzyme and pathway databases

Reactomeⁱ	R-MMU-375281 Hormone ligand-binding receptors R-MMU-418555 G alpha (s) signalling events

Reactomeⁱ

R-MMU-375281 Hormone ligand-binding receptors
R-MMU-418555 G alpha (s) signalling events

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P35378
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000032937 Expressed in 24 organ(s), highest expression level in cumulus cell
CleanExⁱ	MM_FSHR
ExpressionAtlasⁱ	P35378 baseline and differential
Genevisibleⁱ	P35378 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR002272 FSH_rcpt IPR024635 GnHR_TM IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR002131 Gphrmn_rcpt_fam IPR026906 LRR_5 IPR000372 LRRNT IPR034298 TSHR/LHCGR/FSHR
PANTHERⁱ	PTHR24372 PTHR24372, 1 hit PTHR24372:SF5 PTHR24372:SF5, 1 hit
Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit PF12369 GnHR_trans, 1 hit PF13306 LRR_5, 2 hits PF01462 LRRNT, 1 hit
PRINTSⁱ	PR01143 FSHRECEPTOR PR00373 GLYCHORMONER PR00237 GPCRRHODOPSN
SMARTⁱ	View protein in SMART SM00013 LRRNT, 1 hit
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	FSHR_MOUSE
Accessionⁱ	P35378Primary (citable) accession number: P35378 Secondary accession number(s): Q9D4C2, Q9QWV8
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
	Last sequence update:	September 26, 2001
	Last modified:	November 7, 2018
	This is version 168 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P35378 (FSHR_MOUSE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Follicle-stimulating hormone receptor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Endosome

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ