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UniProtKB - P35183 (AST1_YEAST)
Protein
Protein AST1
Gene
AST1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Reroutes mutant ATPase from the vacuole to the cell surface. Participates in membrane traffic. Interacts with PMA1.
GO - Molecular functioni
- oxidoreductase activity Source: InterPro
GO - Biological processi
- protein targeting to membrane Source: SGD
- protein transport into membrane raft Source: SGD
Names & Taxonomyi
Protein namesi | Recommended name: Protein AST1 |
Gene namesi | Name:AST1 Ordered Locus Names:YBL069W ORF Names:YBL06.04, YBL0617 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000000165, AST1 |
VEuPathDBi | FungiDB:YBL069W |
Subcellular locationi
Other locations
Endosome
- late endosome Source: SGD
Golgi apparatus
- Golgi apparatus Source: SGD
Plasma Membrane
- plasma membrane Source: SGD
Other locations
- membrane raft Source: SGD
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000064710 | 1 – 429 | Protein AST1Add BLAST | 429 |
Proteomic databases
MaxQBi | P35183 |
PaxDbi | P35183 |
PRIDEi | P35183 |
PTM databases
iPTMneti | P35183 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 32631, 56 interactors |
IntActi | P35183, 2 interactors |
STRINGi | 4932.YBL069W |
Miscellaneous databases
RNActi | P35183, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | KOG1198, Eukaryota |
GeneTreei | ENSGT00940000176396 |
HOGENOMi | CLU_026673_4_0_1 |
InParanoidi | P35183 |
OMAi | WSYNYTH |
Family and domain databases
InterProi | View protein in InterPro IPR013154, ADH_N IPR011032, GroES-like_sf IPR036291, NAD(P)-bd_dom_sf IPR020843, PKS_ER |
Pfami | View protein in Pfam PF08240, ADH_N, 1 hit |
SMARTi | View protein in SMART SM00829, PKS_ER, 1 hit |
SUPFAMi | SSF50129, SSF50129, 1 hit SSF51735, SSF51735, 1 hit |
i Sequence
Sequence statusi: Complete.
P35183-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKDILKNQD PKLQAMIVEH SAPAPKEIPM DAPVLKRVAR PLRHVKFIPI
60 70 80 90 100
KSLIFHTKTG PMDFSYEKKI KTPIPKNKIV VRVSNVGLNP VDMKIRNGYT
110 120 130 140 150
SSIYGEIGLG REYSGVITEV GENLNYAWHV GDEVYGIYYH PHLAVGCLQS
160 170 180 190 200
SILVDPKVDP ILLRPESVSA EEAAGSLFCL ATGYNILNKL SKNKYLKQDS
210 220 230 240 250
NVLINGGTSS VGMFVIQLLK RHYKLQKKLV IVTSANGPQV LQEKFPDLAD
260 270 280 290 300
EMIFIDYLTC RGKSSKPLRK MLEEKKISQY DPVEDKETIL NYNEGKFDVV
310 320 330 340 350
LDFVGGYDIL SHSSSLIHGG GAYVTTVGDY VANYKEDIFD SWDNPSANAR
360 370 380 390 400
KMFGSIIWSY NYTHYYFDPN AKTASANNDW IEQCGDFLKN GTVKCVVDKV
410 420
YDWKDHKEAF SYMATQRAQG KLIMNVEKF
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 326 – 429 | TVGDY…NVEKF → HCR (PubMed:7992509).CuratedAdd BLAST | 104 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X81843 Genomic DNA Translation: CAA57435.1 Z26879 Genomic DNA Translation: CAA81522.1 Z35831 Genomic DNA Translation: CAA84891.1 Z35829 Genomic DNA Translation: CAA84889.1 BK006936 Genomic DNA Translation: DAA07052.1 |
PIRi | S45588 |
RefSeqi | NP_009484.2, NM_001178309.1 |
Genome annotation databases
EnsemblFungii | YBL069W_mRNA; YBL069W; YBL069W |
GeneIDi | 852209 |
KEGGi | sce:YBL069W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X81843 Genomic DNA Translation: CAA57435.1 Z26879 Genomic DNA Translation: CAA81522.1 Z35831 Genomic DNA Translation: CAA84891.1 Z35829 Genomic DNA Translation: CAA84889.1 BK006936 Genomic DNA Translation: DAA07052.1 |
PIRi | S45588 |
RefSeqi | NP_009484.2, NM_001178309.1 |
3D structure databases
AlphaFoldDBi | P35183 |
SMRi | P35183 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 32631, 56 interactors |
IntActi | P35183, 2 interactors |
STRINGi | 4932.YBL069W |
PTM databases
iPTMneti | P35183 |
Proteomic databases
MaxQBi | P35183 |
PaxDbi | P35183 |
PRIDEi | P35183 |
Genome annotation databases
EnsemblFungii | YBL069W_mRNA; YBL069W; YBL069W |
GeneIDi | 852209 |
KEGGi | sce:YBL069W |
Organism-specific databases
SGDi | S000000165, AST1 |
VEuPathDBi | FungiDB:YBL069W |
Phylogenomic databases
eggNOGi | KOG1198, Eukaryota |
GeneTreei | ENSGT00940000176396 |
HOGENOMi | CLU_026673_4_0_1 |
InParanoidi | P35183 |
OMAi | WSYNYTH |
Miscellaneous databases
PROi | PR:P35183 |
RNActi | P35183, protein |
Family and domain databases
InterProi | View protein in InterPro IPR013154, ADH_N IPR011032, GroES-like_sf IPR036291, NAD(P)-bd_dom_sf IPR020843, PKS_ER |
Pfami | View protein in Pfam PF08240, ADH_N, 1 hit |
SMARTi | View protein in SMART SM00829, PKS_ER, 1 hit |
SUPFAMi | SSF50129, SSF50129, 1 hit SSF51735, SSF51735, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | AST1_YEAST | |
Accessioni | P35183Primary (citable) accession number: P35183 Secondary accession number(s): D6VPT2, P89492 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1994 |
Last sequence update: | February 1, 1995 | |
Last modified: | May 25, 2022 | |
This is version 151 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome II
Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names