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Protein

Adenylate kinase

Gene

adkA

Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + AMP = 2 ADP.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi8 – 16ATP9

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.4.3 6160

Names & Taxonomyi

Protein namesi
Recommended name:
Adenylate kinase (EC:2.7.4.3)
Short name:
AK
Alternative name(s):
ATP-AMP transphosphorylase
Gene namesi
Name:adkA
Synonyms:adk
Ordered Locus Names:Saci_0573
OrganismiSulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Taxonomic identifieri330779 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001018 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001318251 – 194Adenylate kinaseAdd BLAST194

Interactioni

Subunit structurei

Homotrimer.

Protein-protein interaction databases

STRINGi330779.Saci_0573

Structurei

Secondary structure

1194
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP35028
SMRiP35028
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP35028

Family & Domainsi

Sequence similaritiesi

Belongs to the archaeal adenylate kinase family.Curated

Phylogenomic databases

eggNOGiarCOG01039 Archaea
COG2019 LUCA
HOGENOMiHOG000105936
KOiK00939
OMAiHRDEMRK
OrthoDBiPOG093Z0CM4

Family and domain databases

HAMAPiMF_00234 Adenylate_kinase_AdkA, 1 hit
InterProiView protein in InterPro
IPR023477 Adenylate_kinase_AdkA
IPR027417 P-loop_NTPase
PANTHERiPTHR12595:SF2 PTHR12595:SF2, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

P35028-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKIGIVTGIP GVGKSTVLAK VKEILDNQGI NNKIINYGDF MLATALKLGY
60 70 80 90 100
AKDRDEMRKL SVEKQKKLQI DAAKGIAEEA RAGGEGYLFI DTHAVIRTPS
110 120 130 140 150
GYLPGLPSYV ITEINPSVIF LLEADPKIIL SRQKRDTTRN RNDYSDESVI
160 170 180 190
LETINFARYA ATASAVLAGS TVKVIVNVEG DPSIAANEII RSMK
Length:194
Mass (Da):21,110
Last modified:February 1, 1995 - v2
Checksum:iC0AA552D8E541900
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73564 Genomic DNA Translation: CAA51967.1
CP000077 Genomic DNA Translation: AAY79965.1
Y07778 Genomic DNA Translation: CAA69101.1
RefSeqiWP_011277467.1, NC_007181.1

Genome annotation databases

EnsemblBacteriaiAAY79965; AAY79965; Saci_0573
GeneIDi3473211
KEGGisai:Saci_0573
PATRICifig|330779.12.peg.552

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73564 Genomic DNA Translation: CAA51967.1
CP000077 Genomic DNA Translation: AAY79965.1
Y07778 Genomic DNA Translation: CAA69101.1
RefSeqiWP_011277467.1, NC_007181.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NKSX-ray2.57A/B/C/D/E/F1-194[»]
ProteinModelPortaliP35028
SMRiP35028
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi330779.Saci_0573

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY79965; AAY79965; Saci_0573
GeneIDi3473211
KEGGisai:Saci_0573
PATRICifig|330779.12.peg.552

Phylogenomic databases

eggNOGiarCOG01039 Archaea
COG2019 LUCA
HOGENOMiHOG000105936
KOiK00939
OMAiHRDEMRK
OrthoDBiPOG093Z0CM4

Enzyme and pathway databases

BRENDAi2.7.4.3 6160

Miscellaneous databases

EvolutionaryTraceiP35028

Family and domain databases

HAMAPiMF_00234 Adenylate_kinase_AdkA, 1 hit
InterProiView protein in InterPro
IPR023477 Adenylate_kinase_AdkA
IPR027417 P-loop_NTPase
PANTHERiPTHR12595:SF2 PTHR12595:SF2, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiKADA_SULAC
AccessioniPrimary (citable) accession number: P35028
Secondary accession number(s): Q4JB64
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1995
Last modified: October 10, 2018
This is version 103 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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