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Entry version 141 (18 Sep 2019)
Sequence version 1 (01 Feb 1994)
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Protein

Microtubule-associated protein 1A

Gene

Map1a

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Structural protein involved in the filamentous cross-bridging between microtubules and other skeletal elements.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Microtubule-associated protein 1A
Short name:
MAP-1A
Cleaved into the following 2 chains:
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Map1a
Synonyms:Mtap1a
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Rat genome database

More...
RGDi
3042 Map1a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000186021 – 2774Microtubule-associated protein 1AAdd BLAST2774
ChainiPRO_00004183781 – 2541MAP1A heavy chainAdd BLAST2541
ChainiPRO_00000186032542 – 2774MAP1 light chain LC2Add BLAST233

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei114PhosphoserineCombined sources1
Modified residuei117PhosphoserineBy similarity1
Modified residuei118PhosphoserineBy similarity1
Modified residuei121PhosphoserineBy similarity1
Modified residuei155PhosphoserineBy similarity1
Modified residuei177PhosphotyrosineBy similarity1
Modified residuei319PhosphoserineCombined sources1
Modified residuei322PhosphoserineCombined sources1
Modified residuei384PhosphoserineCombined sources1
Modified residuei504PhosphothreonineBy similarity1
Modified residuei526PhosphoserineCombined sources1
Modified residuei527PhosphoserineCombined sources1
Modified residuei604PhosphoserineBy similarity1
Modified residuei611PhosphoserineCombined sources1
Modified residuei643PhosphoserineCombined sources1
Modified residuei663PhosphothreonineCombined sources1
Modified residuei666PhosphoserineCombined sources1
Modified residuei677PhosphoserineBy similarity1
Modified residuei690PhosphoserineCombined sources1
Modified residuei785PhosphoserineBy similarity1
Modified residuei872PhosphoserineBy similarity1
Modified residuei875PhosphoserineBy similarity1
Modified residuei876PhosphoserineBy similarity1
Modified residuei889PhosphoserineCombined sources1
Modified residuei892PhosphothreonineCombined sources1
Modified residuei894PhosphoserineCombined sources1
Modified residuei898PhosphoserineBy similarity1
Modified residuei907PhosphoserineCombined sources1
Modified residuei980PhosphoserineCombined sources1
Modified residuei990PhosphoserineCombined sources1
Modified residuei998PhosphoserineBy similarity1
Modified residuei1007PhosphoserineCombined sources1
Modified residuei1013PhosphoserineCombined sources1
Modified residuei1022PhosphoserineCombined sources1
Modified residuei1029PhosphoserineCombined sources1
Modified residuei1037PhosphoserineCombined sources1
Modified residuei1061PhosphoserineBy similarity1
Modified residuei1132PhosphoserineCombined sources1
Modified residuei1134PhosphoserineCombined sources1
Modified residuei1148PhosphoserineBy similarity1
Modified residuei1160PhosphoserineBy similarity1
Modified residuei1178PhosphoserineCombined sources1
Modified residuei1188PhosphoserineCombined sources1
Modified residuei1191PhosphoserineCombined sources1
Modified residuei1197PhosphoserineBy similarity1
Modified residuei1206PhosphoserineCombined sources1
Modified residuei1209PhosphoserineCombined sources1
Modified residuei1252PhosphoserineCombined sources1
Modified residuei1280PhosphoserineCombined sources1
Modified residuei1301PhosphoserineCombined sources1
Modified residuei1304PhosphoserineCombined sources1
Modified residuei1307PhosphoserineBy similarity1
Modified residuei1504PhosphoserineBy similarity1
Modified residuei1568PhosphoserineBy similarity1
Modified residuei1574PhosphoserineCombined sources1
Modified residuei1594PhosphoserineCombined sources1
Modified residuei1622PhosphoserineCombined sources1
Modified residuei1643PhosphoserineCombined sources1
Modified residuei1715PhosphoserineBy similarity1
Modified residuei1742PhosphoserineCombined sources1
Modified residuei1757PhosphoserineCombined sources1
Modified residuei1763PhosphoserineCombined sources1
Modified residuei1767PhosphoserineCombined sources1
Modified residuei1772PhosphothreonineCombined sources1
Modified residuei1778PhosphoserineBy similarity1
Modified residuei1784PhosphoserineCombined sources1
Modified residuei1897PhosphoserineCombined sources1
Modified residuei1923PhosphothreonineBy similarity1
Modified residuei1988PhosphoserineCombined sources1
Modified residuei2026PhosphothreonineCombined sources1
Modified residuei2043PhosphoserineCombined sources1
Modified residuei2077PhosphoserineCombined sources1
Modified residuei2204PhosphoserineCombined sources1
Modified residuei2221PhosphoserineCombined sources1
Modified residuei2225PhosphoserineCombined sources1
Modified residuei2228PhosphoserineCombined sources1
Modified residuei2229PhosphoserineCombined sources1
Modified residuei2260PhosphoserineCombined sources1
Modified residuei2424PhosphoserineBy similarity1
Modified residuei2620PhosphoserineBy similarity1
Modified residuei2635PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated by CSNK1D.1 Publication
LC2 is generated from MAP1A by proteolytic processing. It is free to associate with both MAP1A and MAP1B.

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P34926

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P34926

PRoteomics IDEntifications database

More...
PRIDEi
P34926

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P34926

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P34926

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P34926

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Brain, heart and muscle.

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed late during neuronal development appearing when axons and dendrites begin to solidify and stabilize their morphology.

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins.

Interacts with guanylate kinase-like domain of DLG1, DLG2 and DLG4. Binds to CSNK1D.

Interacts with TIAM2 (By similarity). MAP1 light chain LC2:

Interacts with ELAVL4 (By similarity).

By similarity2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
247217, 6 interactors

Database of interacting proteins

More...
DIPi
DIP-29265N

Protein interaction database and analysis system

More...
IntActi
P34926, 6 interactors

Molecular INTeraction database

More...
MINTi
P34926

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000019320

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati336 – 33813
Repeati415 – 41723
Repeati420 – 42233
Repeati424 – 42643
Repeati427 – 42953
Repeati431 – 43363
Repeati436 – 43873
Repeati440 – 44283
Repeati444 – 44693
Repeati449 – 451103
Repeati539 – 541113

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni336 – 54111 X 3 AA repeats of K-K-[DE]Add BLAST206

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi309 – 496Lys-rich (basic)Add BLAST188

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The basic region containing the repeats may be responsible for the binding of MAP1A to microtubules.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MAP1 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3592 Eukaryota
ENOG410XRYM LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231839

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P34926

KEGG Orthology (KO)

More...
KOi
K10429

Database of Orthologous Groups

More...
OrthoDBi
86642at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P34926

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026074 MAP1
IPR015656 MAP1A
IPR036866 RibonucZ/Hydroxyglut_hydro

The PANTHER Classification System

More...
PANTHERi
PTHR13843 PTHR13843, 1 hit
PTHR13843:SF6 PTHR13843:SF6, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56281 SSF56281, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P34926-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGVAEFSEY VSETVDVPSP FDLLEPPTSG GFLKLSKPCC YIFPGGRGDS
60 70 80 90 100
ALFAVNGFNI LVDGGSDRKS CFWKLVRHLD RIDSVLLTHI GADNLPGING
110 120 130 140 150
LLQRKVAELE EEQSQGSSSY SDWVKNLISP ELGVVFFNVP DKLRLPDASR
160 170 180 190 200
KAKRSIEEAC LTLQHLNRLG IQAEPLYRVV SNTIEPLTLF HKMGVGRLDM
210 220 230 240 250
YVLNPVKDSK EMQFLMQKWA GNSKAKTGIV LANGKEAEIS VPYLTSITAL
260 270 280 290 300
VVWLPANPTE KIVRVLFPGN APQNKILEGL EKLRHLDFLR YPVATQKDLA
310 320 330 340 350
AGAVPANLKP SKIKHRADSK ESLKAAPKTA VSKLAKREEV LEEGAKEARS
360 370 380 390 400
ELAKELAKTE KKAKEPSEKP PEKPSKSERV RGESSEALKA EKRRLIKDKA
410 420 430 440 450
GKKHLKEKIS KLEEKKDKEK KEIKKERKEL KKEEGRKEEK KDAKKDEKRK
460 470 480 490 500
DTKPEVKKLS KPDLKPFTPE VRKTLYKAKA PGRVKVDKGR AARGEKELSS
510 520 530 540 550
EPRTPPAQKG AAPPAAVSGH RELALSSPED LTQDFEELKR EERGLLAEQR
560 570 580 590 600
DTGLGEKPLP ADATEQGHPS AAIQVTQPSG PVLEGEHVER EKEVVPDSPG
610 620 630 640 650
DKGSTNRGPD SGAEVEKEKE TWEERKQREA ELGPENTAAR EESEAEVKED
660 670 680 690 700
VIEKAELEEM EETHPSDEEG EETKAESFYQ KHTQEALKAS PKSREALGGR
710 720 730 740 750
DLGFQGKAPE KETASFLSSL ATPAGATEHV SYIQDETIPG YSETEQTISD
760 770 780 790 800
EEIHDEPDER PAPPRFPTST YDLSGPEGPG PFEASQAADS AVPASSSKTY
810 820 830 840 850
GAPETELTYP PNMVAAPLAE EEHVSSATSI TECDKLSSFA TSVAEDQSVA
860 870 880 890 900
SLTAPQTEET GKSSLLLDTV TSIPSSRTEA TQGLDYVPSA GTISPTSSLE
910 920 930 940 950
EDKGFKSPPC EDFSVTGESE KKGETVGRGL SGEKAVGKEE KYVVTSEKLS
960 970 980 990 1000
GQYAAVFGAP GHTLPPGEPA LGEVEERCLS PDDSTVKMAS PPPSGPPSAA
1010 1020 1030 1040 1050
HTPFHQSPVE DKSEPRDFQE DSWGETKHSP GVSKEDSEEQ TVKPGPEEGT
1060 1070 1080 1090 1100
SEEGKGPPTR SPQAQDMPVS IAGGQTGCTI QLLPEQDKAI VFETGEAGSN
1110 1120 1130 1140 1150
LGAGTLPGEV RTSTEEATEP QKDEVLRFTD QSLSPEDAES LSVLSVVSPD
1160 1170 1180 1190 1200
TTKQEATPRS PCSLKEQQPH KDLWPMVSPE DTQSLSFSEE SPSKETSLDI
1210 1220 1230 1240 1250
SSKQLSPESL GTLQFGELNL GKEERGPVMK AEDDSCHLAP VSIPEPHRAT
1260 1270 1280 1290 1300
VSPSTDETPA GTLPGGSFSH SALSVDRKHS PGEITGPGGH FMTSDSSLTK
1310 1320 1330 1340 1350
SPESLSSPAM EDLAVEWEGK APGKEKEPEL KSETRQQKGQ ILPEKVAVVE
1360 1370 1380 1390 1400
QDLIIHQKDG ALDEENKPGR QQDKTPEQKG RDLDEKDTAA ELDKGPEPKE
1410 1420 1430 1440 1450
KDLDREDQGQ RAGPPAEKDK ASEQRDTDLQ QTQATEPRDR AQERRDSEEK
1460 1470 1480 1490 1500
DKSLELRDRT PEEKDRILVQ EDRAPEHSIP EPTQTDRAPD RKGTDDKEQK
1510 1520 1530 1540 1550
EEASEEKEQV LEQKDWALGK EGETLDQEAR TAEQKDETLK EDKTQGQKSS
1560 1570 1580 1590 1600
FVEDKTTTSK ETVLDQKSAE KADSVEQQDG AALEKTRALG LEESPAEGSK
1610 1620 1630 1640 1650
AREQEKKYWK EQDVVQGWRE TSPTRGEPVG GQKEPVPAWE GKSPEQEVRY
1660 1670 1680 1690 1700
WRDRDITLQQ DAYWRELSCD RKVWFPHELD GQGARPRYCE ERESTFLDEG
1710 1720 1730 1740 1750
PDEQEITPLQ HTPRSPWTSD FKDFQEPLPQ KGLEVERWLA ESPVGLPPEE
1760 1770 1780 1790 1800
EDKLTRSPFE IISPPASPPE MTGQRVPSAP GQESPVPDTE STAPMRNEPT
1810 1820 1830 1840 1850
TPSWLAEIPP WVPKDRPLPP APLSPAPAPP TPAPEPHTPV PFSWGLAEYD
1860 1870 1880 1890 1900
SVVAAVQEGA AELEGGPYSP LGKDYRKAEG EREGEGGAGA PDSSSFSPKV
1910 1920 1930 1940 1950
PEAGESLATR DTEQTEPEQR EPTPYPDERS FQYADIYEQM MLTGLGPACP
1960 1970 1980 1990 2000
TREPPLGASG DWPPHLSTKE EAAGCNTSAE KETSSPASPQ NLQSDTPAFS
2010 2020 2030 2040 2050
YASLAGPAVP PRQEPDPGPN VEPSITPPAV PPRAPISLSK DLSPPLNGST
2060 2070 2080 2090 2100
VSCSPDRRTP SPKETGRGHW DDGTNDSDLE KGAREQPEKE TRSPSPHHPM
2110 2120 2130 2140 2150
PMGHSSLWPE TEAYSSLSSD SHLGSVRPSL DFPASAFGFS SLQPAPPQLP
2160 2170 2180 2190 2200
SPAEPRSAPC GSLAFSGDRA LALVPGTPTR TRHDEYLEVT KAPSLDSSLP
2210 2220 2230 2240 2250
QLPSPSSPGG PLLSNLPRPA SPALSEGSSS EATTPVISSV AERFPPGLEA
2260 2270 2280 2290 2300
AEQSAEGLGS GKESAAHSLW DLTPLSPAPS ASLDLAPAPA PAPAPAPGLP
2310 2320 2330 2340 2350
GDLGDGTLPC RPECTGELTK KPSPFLSPSG DHEANGPGET SLNPPGFVTA
2360 2370 2380 2390 2400
TAEKEEAEAP HAWERGSWPE GAERSSRPDT LLSSEQPLRP GKSSGGPPCS
2410 2420 2430 2440 2450
LSSEVEAGPQ GCATDPRPHC GELSPSFLNP PLPPSTDDSD LSTEEARLAG
2460 2470 2480 2490 2500
KGGRRRVGRP GATGGPCPMA DETPPTSASD SGSSQSDSDV PPETEECPSI
2510 2520 2530 2540 2550
TAEAALDSDE DGDFLPVDKA GGVSGTHHPR PGHDPPPTPL PDPRPSPPRP
2560 2570 2580 2590 2600
DVCMADPEGL SSESGRVERL REKGRPGRRA PGRAKPASPA RRLDIRGKRS
2610 2620 2630 2640 2650
PTPGKGPVDR TSRTVPRPRS TPSQVTSAEE KDGHSPMSKG LVNGLKAGST
2660 2670 2680 2690 2700
ALGSKGGSGP PVYVDLAYIP NHCSGKTADQ DFFRRVRASY YVVSGNDPAN
2710 2720 2730 2740 2750
GEPSRAVLDA LLEGKAQWGE NLQVTLIPTH DTEVTREWYQ QTHEQQQQLN
2760 2770
VLVLASSSTV VMQDESFPAC KIEF
Length:2,774
Mass (Da):299,531
Last modified:February 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3DEF74427BA9D7D7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V7U2G3V7U2_RAT
Microtubule-associated protein 1 A,...
Map1a Mtap1a, rCG_27021
2,776Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2K5C6A0A0G2K5C6_RAT
Microtubule-associated protein 1A
Map1a
3,014Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
M83196 mRNA Translation: AAB48069.1

Protein sequence database of the Protein Information Resource

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PIRi
A43359

NCBI Reference Sequences

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RefSeqi
NP_112257.1, NM_030995.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
25152

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
rno:25152

UCSC genome browser

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UCSCi
RGD:3042 rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M83196 mRNA Translation: AAB48069.1
PIRiA43359
RefSeqiNP_112257.1, NM_030995.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi247217, 6 interactors
DIPiDIP-29265N
IntActiP34926, 6 interactors
MINTiP34926
STRINGi10116.ENSRNOP00000019320

PTM databases

iPTMnetiP34926
PhosphoSitePlusiP34926
SwissPalmiP34926

Proteomic databases

jPOSTiP34926
PaxDbiP34926
PRIDEiP34926

Genome annotation databases

GeneIDi25152
KEGGirno:25152
UCSCiRGD:3042 rat

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
4130
RGDi3042 Map1a

Phylogenomic databases

eggNOGiKOG3592 Eukaryota
ENOG410XRYM LUCA
HOGENOMiHOG000231839
InParanoidiP34926
KOiK10429
OrthoDBi86642at2759
PhylomeDBiP34926

Miscellaneous databases

Protein Ontology

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PROi
PR:P34926

Family and domain databases

InterProiView protein in InterPro
IPR026074 MAP1
IPR015656 MAP1A
IPR036866 RibonucZ/Hydroxyglut_hydro
PANTHERiPTHR13843 PTHR13843, 1 hit
PTHR13843:SF6 PTHR13843:SF6, 1 hit
SUPFAMiSSF56281 SSF56281, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMAP1A_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P34926
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: September 18, 2019
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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