UniProtKB - P34811 (EFGC1_SOYBN)
Elongation factor G-1, chloroplastic
fusA1
Functioni
Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
UniRule annotation: polypeptide chain elongation Pathwayi
This protein is involved in the pathway polypeptide chain elongation, which is part of Protein biosynthesis.UniRule annotationView all proteins of this organism that are known to be involved in the pathway polypeptide chain elongation and in Protein biosynthesis.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 107 – 114 | GTPUniRule annotation | 8 | |
Nucleotide bindingi | 171 – 175 | GTPUniRule annotation | 5 | |
Nucleotide bindingi | 225 – 228 | GTPUniRule annotation | 4 |
GO - Molecular functioni
- GTPase activity Source: GO_Central
- GTP binding Source: UniProtKB-UniRule
- translation elongation factor activity Source: UniProtKB-UniRule
GO - Biological processi
- mitochondrial translation Source: GO_Central
- ribosome disassembly Source: GO_Central
Keywordsi
Molecular function | Elongation factor |
Biological process | Protein biosynthesis |
Ligand | GTP-binding, Nucleotide-binding |
Enzyme and pathway databases
UniPathwayi | UPA00345 |
Names & Taxonomyi
Protein namesi | Recommended name: Elongation factor G-1, chloroplasticShort name: cEF-G 1UniRule annotation |
Gene namesi | Name:fusA1 |
Organismi | Glycine max (Soybean) (Glycine hispida) |
Taxonomic identifieri | 3847 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › fabids › Fabales › Fabaceae › Papilionoideae › 50 kb inversion clade › NPAAA clade › indigoferoid/millettioid clade › Phaseoleae › Glycine › Glycine subgen. Soja |
Proteomesi |
|
Subcellular locationi
Chloroplast
- chloroplast UniRule annotation
Chloroplast
- chloroplast Source: UniProtKB-SubCell
Mitochondrion
- mitochondrion Source: GOC
Keywords - Cellular componenti
Chloroplast, PlastidPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 86 | ChloroplastUniRule annotationAdd BLAST | 86 | |
ChainiPRO_0000007439 | 87 – 787 | Elongation factor G-1, chloroplasticAdd BLAST | 701 |
Proteomic databases
PRIDEi | P34811 |
ProMEXi | P34811 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 98 – 373 | tr-type GAdd BLAST | 276 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 14 – 34 | DisorderedSequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 14 – 32 | Polar residuesSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG0465, Eukaryota |
HOGENOMi | CLU_002794_4_1_1 |
InParanoidi | P34811 |
OMAi | MDDMVGG |
OrthoDBi | 637899at2759 |
Family and domain databases
CDDi | cd16262, EFG_III, 1 hit cd01434, EFG_mtEFG1_IV, 1 hit cd03713, EFG_mtEFG_C, 1 hit |
Gene3Di | 3.30.230.10, 1 hit 3.40.50.300, 1 hit |
HAMAPi | MF_00054_B, EF_G_EF_2_B, 1 hit MF_03063, EF_G_plantC, 1 hit |
InterProi | View protein in InterPro IPR030848, EF_G_plantC IPR041095, EFG_II IPR009022, EFG_III IPR035647, EFG_III/V IPR035649, EFG_V IPR000640, EFG_V-like IPR004161, EFTu-like_2 IPR031157, G_TR_CS IPR027417, P-loop_NTPase IPR020568, Ribosomal_S5_D2-typ_fold IPR014721, Ribosomal_S5_D2-typ_fold_subgr IPR005225, Small_GTP-bd_dom IPR000795, T_Tr_GTP-bd_dom IPR009000, Transl_B-barrel_sf IPR004540, Transl_elong_EFG/EF2 IPR005517, Transl_elong_EFG/EF2_IV |
Pfami | View protein in Pfam PF00679, EFG_C, 1 hit PF14492, EFG_III, 1 hit PF03764, EFG_IV, 1 hit PF00009, GTP_EFTU, 1 hit PF03144, GTP_EFTU_D2, 1 hit |
PRINTSi | PR00315, ELONGATNFCT |
SMARTi | View protein in SMART SM00838, EFG_C, 1 hit SM00889, EFG_IV, 1 hit |
SUPFAMi | SSF50447, SSF50447, 1 hit SSF52540, SSF52540, 1 hit SSF54211, SSF54211, 1 hit SSF54980, SSF54980, 2 hits |
TIGRFAMsi | TIGR00484, EF-G, 1 hit TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS00301, G_TR_1, 1 hit PS51722, G_TR_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
10 20 30 40 50
MAAESSLRVA TPTLCNLNGS QRRPTTTTLS PLRFMGFRPR PSSHSLTSSS
60 70 80 90 100
LSHFFGSTRI HSNSSSSYSS ISRQHAPRRN FSVFAMSADD AKRSVPLKDY
110 120 130 140 150
RNIGIMAHID AGKTTTTERI LYYTGRNYKI GEVHEGTATM DWMEQEQERG
160 170 180 190 200
ITITSAATTT FWNKHRINII DTPGHVDFTL EVERALRVLD GAICLFDSVA
210 220 230 240 250
GVEPQSETVW RQADKYGVPR ICFVNKMDRL GANFYRTRDM IVTNLGAKPL
260 270 280 290 300
VIQLPIGSED NFKGVIDLVR NKAIVWSGEE LGAKFDIVDI PEDLQEQAQD
310 320 330 340 350
YRAQMIENIV EFDDQAMENY LEGIEPDEET IKKLIRKGTI SASFVPVMCG
360 370 380 390 400
SAFKNKGVQP LLDAVVDYLP SPLDLPAMKG SDPENPEATI ERLASDDEPF
410 420 430 440 450
AGLAFKIMSD PFVGSLTFVR VYAGKLGAGS YVLNANKGKK ERIGRLLEMH
460 470 480 490 500
ANSRDDVKVA LAGDIIALAG LKDTITGETL CDPDNPIVLE RMDFPDPVIK
510 520 530 540 550
VAIEPKTKAD VDKMATGLIK LAQEDPSFHF SRDEEINQTV IEGMGELHLE
560 570 580 590 600
IIVDRLKREF KVEANVGAPQ VNYRESISKI SEVKYVHKKQ SGGQGQFADI
610 620 630 640 650
TVRFEPMDPG SGYEFKSEIK GGAVPREYIP GVMKGLEECM SNGVLAGFPV
660 670 680 690 700
VDVRAVLTDG SYHDVDSSVL AFQLAARGAF REGIRKAGPR MLEPIMKVEV
710 720 730 740 750
VTPEEHLGDV IGDLNSRRGQ INSFGDKPGG LKVVDSLVPL AEMFQYVSTL
760 770 780
RGMTKGRASY TMQLAMFDVV PQHIQNQLAT KEQEVAA
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0R0FND6 | A0A0R0FND6_SOYBN | Elongation factor G, chloroplastic | GLYMA_17G137600 | 787 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 89 | D → DG in CAA50573 (PubMed:8357836).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X71439 Genomic DNA Translation: CAA50573.1 Different initiation. BT096075 Genomic DNA No translation available. |
PIRi | S35701 |
RefSeqi | XP_006600825.1, XM_006600762.2 |
Genome annotation databases
EnsemblPlantsi | KRH04069; KRH04069; GLYMA_17G137600 |
Gramenei | KRH04069; KRH04069; GLYMA_17G137600 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X71439 Genomic DNA Translation: CAA50573.1 Different initiation. BT096075 Genomic DNA No translation available. |
PIRi | S35701 |
RefSeqi | XP_006600825.1, XM_006600762.2 |
3D structure databases
SMRi | P34811 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3847.GLYMA17G14650.1 |
Proteomic databases
PRIDEi | P34811 |
ProMEXi | P34811 |
Genome annotation databases
EnsemblPlantsi | KRH04069; KRH04069; GLYMA_17G137600 |
Gramenei | KRH04069; KRH04069; GLYMA_17G137600 |
Phylogenomic databases
eggNOGi | KOG0465, Eukaryota |
HOGENOMi | CLU_002794_4_1_1 |
InParanoidi | P34811 |
OMAi | MDDMVGG |
OrthoDBi | 637899at2759 |
Enzyme and pathway databases
UniPathwayi | UPA00345 |
Gene expression databases
Genevisiblei | P34811, GM |
Family and domain databases
CDDi | cd16262, EFG_III, 1 hit cd01434, EFG_mtEFG1_IV, 1 hit cd03713, EFG_mtEFG_C, 1 hit |
Gene3Di | 3.30.230.10, 1 hit 3.40.50.300, 1 hit |
HAMAPi | MF_00054_B, EF_G_EF_2_B, 1 hit MF_03063, EF_G_plantC, 1 hit |
InterProi | View protein in InterPro IPR030848, EF_G_plantC IPR041095, EFG_II IPR009022, EFG_III IPR035647, EFG_III/V IPR035649, EFG_V IPR000640, EFG_V-like IPR004161, EFTu-like_2 IPR031157, G_TR_CS IPR027417, P-loop_NTPase IPR020568, Ribosomal_S5_D2-typ_fold IPR014721, Ribosomal_S5_D2-typ_fold_subgr IPR005225, Small_GTP-bd_dom IPR000795, T_Tr_GTP-bd_dom IPR009000, Transl_B-barrel_sf IPR004540, Transl_elong_EFG/EF2 IPR005517, Transl_elong_EFG/EF2_IV |
Pfami | View protein in Pfam PF00679, EFG_C, 1 hit PF14492, EFG_III, 1 hit PF03764, EFG_IV, 1 hit PF00009, GTP_EFTU, 1 hit PF03144, GTP_EFTU_D2, 1 hit |
PRINTSi | PR00315, ELONGATNFCT |
SMARTi | View protein in SMART SM00838, EFG_C, 1 hit SM00889, EFG_IV, 1 hit |
SUPFAMi | SSF50447, SSF50447, 1 hit SSF52540, SSF52540, 1 hit SSF54211, SSF54211, 1 hit SSF54980, SSF54980, 2 hits |
TIGRFAMsi | TIGR00484, EF-G, 1 hit TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS00301, G_TR_1, 1 hit PS51722, G_TR_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | EFGC1_SOYBN | |
Accessioni | P34811Primary (citable) accession number: P34811 Secondary accession number(s): I1MUX0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1994 |
Last sequence update: | January 22, 2014 | |
Last modified: | February 23, 2022 | |
This is version 127 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families