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Entry version 146 (18 Sep 2019)
Sequence version 1 (01 Feb 1994)
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Protein

Protein SCD5

Gene

SCD5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in vesicular transport at a late stage of the secretory pathway.

Miscellaneous

Present with 704 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:G3O-33806-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein SCD5
Alternative name(s):
Protein FTB1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SCD5
Synonyms:FTB1
Ordered Locus Names:YOR329C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XV

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
FungiDB:YOR329C

Saccharomyces Genome Database

More...
SGDi
S000005856 SCD5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000976211 – 872Protein SCD5Add BLAST872

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei564PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

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MaxQBi
P34758

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P34758

PRoteomics IDEntifications database

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PRIDEi
P34758

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P34758

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Putative 10-formyl-tetrahydrofolate binding protein.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
GLC7P325984EBI-16685,EBI-13715

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
34714, 56 interactors

Database of interacting proteins

More...
DIPi
DIP-1341N

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...
ELMi
P34758

Protein interaction database and analysis system

More...
IntActi
P34758, 6 interactors

Molecular INTeraction database

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MINTi
P34758

STRING: functional protein association networks

More...
STRINGi
4932.YOR329C

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati405 – 4241-1Add BLAST20
Repeati439 – 4581-2Add BLAST20
Repeati479 – 4981-3Add BLAST20
Repeati534 – 5452-1Add BLAST12
Repeati564 – 5752-2Add BLAST12
Repeati593 – 6042-3Add BLAST12
Repeati608 – 6192-4Add BLAST12
Repeati623 – 6342-5Add BLAST12
Repeati636 – 6472-5Add BLAST12
Repeati650 – 6612-7Add BLAST12
Repeati683 – 6942-8Add BLAST12
Repeati717 – 7282-9Add BLAST12

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni405 – 4483 X 20 AA approximate repeatsAdd BLAST44
Regioni534 – 7289 X 12 AA approximate repeatsAdd BLAST195

Keywords - Domaini

Repeat

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000000799

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P34758

Identification of Orthologs from Complete Genome Data

More...
OMAi
IRTYLRW

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P34758-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSFDWLNVPG LDLSSGDQAE KRPSNGLGPP SVSFDFGINT AAPHDSSFWD
60 70 80 90 100
QGSRSHSDTT LSYRNNHSNT AADNATNVSS PQKDNPPNGE VRTLSGGDVY
110 120 130 140 150
AESPEDMQVP LSLSQNQLTH EEIRTYLRWY HYICLRTHGK LVRLNDVFRF
160 170 180 190 200
LTNFNLSQKV KDRIVEIFRS CKNALNIGQF FAVLRLVSRA IIYGILPLRR
210 220 230 240 250
MILEKAPVPK PRPILSSENH EEVYEEVEDD DSSAKTGDQK VDFDSFASLL
260 270 280 290 300
LTGKTTRKRV RRRIKNLNFK SKKVRFSEHI TFQDPPNLNQ ESSNNSEARK
310 320 330 340 350
QDPDAEDEDQ DSNNDSPLDF TLPMDQLLKR LYKRRKNSGL VSSLPSEQQE
360 370 380 390 400
TEEEKKVLED MKDSLSHFKQ IQTVDSASLP ISSVFLQNGN TLPTSNVNNT
410 420 430 440 450
TVPQQLPLEP LKPTATGSAN HLVREEYNQG LHPSNGAIQT GLQPLKPTAT
460 470 480 490 500
GSANYLMRSH MEQPQSIKPS STPETVTNSG GLQPLKPTAT GSANYLMKQH
510 520 530 540 550
ISPSVNNPVS SMFQAQFTNQ SSSPQSTGPA FLNSPNITLP QSNQQQPYQE
560 570 580 590 600
VNPTQAKIEP SNISPQHTYS NNVRINNGNI VSMPKVEITG AFPPQNTLPQ
610 620 630 640 650
HQQSHLLSPQ NTIPQHQRSQ LISPQNTFTQ NQPILSPQHT YSNNQATMIS
660 670 680 690 700
PQNTYTNNQQ QPQHLPPPPP PRAQQQQQGA IVPPQHMYSN VQKQNNLVPT
710 720 730 740 750
QPSYTNSPSI QSPNFLSPQN AANSYFQSLL SSSPSPNPTP SNASTVNGNN
760 770 780 790 800
ASNGISSFQN TSAAMNNTQS HQTYIQQQQQ QQTQQRIYGG QLSQMQQHPG
810 820 830 840 850
QLHLNNSDIH SQPNKPNYGM LGQQVHQQQQ QQQQQFPFTA DVNRSNSSDI
860 870
LGNLQSLQQQ VDALQIQYNR RP
Length:872
Mass (Da):97,305
Last modified:February 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC60F5BE8808E1D31
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U03492 mRNA Translation: AAB09719.1
U42227 Genomic DNA Translation: AAA85443.1
Z49821 Genomic DNA Translation: CAA89976.1
Z75237 Genomic DNA Translation: CAA99650.1
BK006948 Genomic DNA Translation: DAA11092.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S62061

NCBI Reference Sequences

More...
RefSeqi
NP_014974.3, NM_001183749.3

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YOR329C_mRNA; YOR329C; YOR329C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
854507

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YOR329C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U03492 mRNA Translation: AAB09719.1
U42227 Genomic DNA Translation: AAA85443.1
Z49821 Genomic DNA Translation: CAA89976.1
Z75237 Genomic DNA Translation: CAA99650.1
BK006948 Genomic DNA Translation: DAA11092.1
PIRiS62061
RefSeqiNP_014974.3, NM_001183749.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi34714, 56 interactors
DIPiDIP-1341N
ELMiP34758
IntActiP34758, 6 interactors
MINTiP34758
STRINGi4932.YOR329C

PTM databases

iPTMnetiP34758

Proteomic databases

MaxQBiP34758
PaxDbiP34758
PRIDEiP34758

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOR329C_mRNA; YOR329C; YOR329C
GeneIDi854507
KEGGisce:YOR329C

Organism-specific databases

EuPathDBiFungiDB:YOR329C
SGDiS000005856 SCD5

Phylogenomic databases

HOGENOMiHOG000000799
InParanoidiP34758
OMAiIRTYLRW

Enzyme and pathway databases

BioCyciYEAST:G3O-33806-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P34758

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCD5_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P34758
Secondary accession number(s): D6W326
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: September 18, 2019
This is version 146 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names
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