SDC2

Functionⁱ

Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).By similarity

GO - Molecular functionⁱ

identical protein binding
Source: IntAct
Inferred from physical interactionⁱ
- 18093920
- 21988832
PDZ domain binding
Source: BHF-UCL
Inferred from physical interactionⁱ
- 18256285

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell migration Source: GO_Central
cellular protein metabolic process Source: Reactome
dendrite morphogenesis Source: GO_Central
ephrin receptor signaling pathway Source: Reactome
glycosaminoglycan biosynthetic process Source: Reactome
glycosaminoglycan catabolic process Source: Reactome
leukocyte migration Source: Reactome
post-translational protein modification Source: Reactome
regulation of dendrite morphogenesis Source: UniProtKB
retinoid metabolic process Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Differentiation, Neurogenesis

Biological process

Differentiation, Neurogenesis

Enzyme and pathway databases

Reactomeⁱ	R-HSA-1971475 A tetrasaccharide linker sequence is required for GAG synthesis R-HSA-2022928 HS-GAG biosynthesis R-HSA-2024096 HS-GAG degradation R-HSA-202733 Cell surface interactions at the vascular wall R-HSA-3000170 Syndecan interactions R-HSA-3560783 Defective B4GALT7 causes EDS, progeroid type R-HSA-3560801 Defective B3GAT3 causes JDSSDHD R-HSA-3656237 Defective EXT2 causes exostoses 2 R-HSA-3656253 Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-3928662 EPHB-mediated forward signaling R-HSA-4420332 Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-8957275 Post-translational protein phosphorylation R-HSA-975634 Retinoid metabolism and transport
SIGNORⁱ	P34741

Reactomeⁱ

R-HSA-1971475 A tetrasaccharide linker sequence is required for GAG synthesis
R-HSA-2022928 HS-GAG biosynthesis
R-HSA-2024096 HS-GAG degradation
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-3000170 Syndecan interactions
R-HSA-3560783 Defective B4GALT7 causes EDS, progeroid type
R-HSA-3560801 Defective B3GAT3 causes JDSSDHD
R-HSA-3656237 Defective EXT2 causes exostoses 2
R-HSA-3656253 Defective EXT1 causes exostoses 1, TRPS2 and CHDS
R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-3928662 EPHB-mediated forward signaling
R-HSA-4420332 Defective B3GALT6 causes EDSP2 and SEMDJL1
R-HSA-8957275 Post-translational protein phosphorylation
R-HSA-975634 Retinoid metabolism and transport

SIGNORⁱ

P34741

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Syndecan-2 Short name: SYND2 Alternative name(s): Fibroglycan Heparan sulfate proteoglycan core protein Short name: HSPG CD_antigen: CD362
Gene namesⁱ	Name:SDC2 Synonyms:HSPG1
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 8

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000169439.11
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:10659 SDC2
MIMⁱ	142460 gene
neXtProtⁱ	NX_P34741

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	19 – 144	ExtracellularSequence analysisAdd BLAST	126
Transmembraneⁱ	145 – 169	HelicalSequence analysisAdd BLAST	25
Topological domainⁱ	170 – 201	CytoplasmicSequence analysisAdd BLAST	32

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6383
Open Targets More...OpenTargetsⁱ	ENSG00000169439
PharmGKBⁱ	PA35589

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB00020 Sargramostim

DrugBankⁱ

DB00020 Sargramostim

Polymorphism and mutation databases

BioMutaⁱ	SDC2
DMDMⁱ	158962336

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 18	Sequence analysisAdd BLAST		18
ChainⁱPRO_0000033503	19 – 201	Syndecan-2Add BLAST		183

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	41	O-linked (Xyl...) (heparan sulfate) serineSequence analysis	1
Glycosylationⁱ	55	O-linked (Xyl...) (heparan sulfate) serineSequence analysis	1
Glycosylationⁱ	57	O-linked (Xyl...) (heparan sulfate) serineSequence analysis	1
Glycosylationⁱ	101	O-linked (GalNAc...) threonine1 Publication	1
Modified residueⁱ	115	Phosphoserine; by FAM20C1 Publication	1
Modified residueⁱ	187	PhosphoserineCombined sources	1

Post-translational modificationⁱ

O-glycosylated with core 1 or possibly core 8 glycans. Contains heparan sulfate.1 Publication

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Siteⁱ	142 – 143	Cleavage of ectodomainSequence analysis		2

Keywords - PTMⁱ

Glycoprotein, Heparan sulfate, Phosphoprotein, Proteoglycan

Proteomic databases

EPDⁱ	P34741
PaxDbⁱ	P34741
PeptideAtlas More...PeptideAtlasⁱ	P34741
PRIDEⁱ	P34741
ProteomicsDBⁱ	54941

PTM databases

GlyConnectⁱ	707
iPTMnetⁱ	P34741
PhosphoSitePlusⁱ	P34741
UniCarbKBⁱ	P34741

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000169439
CleanExⁱ	HS_SDC2
ExpressionAtlasⁱ	P34741 baseline and differential
Genevisibleⁱ	P34741 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB025123 HPA044416

HPAⁱ

CAB025123
HPA044416

Interactionⁱ

Subunit structureⁱ

Interacts (via cytoplasmic domain) with SARM1 (By similarity). Forms a complex with SDCBP and PDCD6IP (PubMed:22660413).By similarity1 Publication

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
itself		4	EBI-1172957,EBI-1172957
CASK	O14936	2	EBI-1172957,EBI-1215506
NF1	P21359	4	EBI-1172957,EBI-1172917
SDC1	P18827	2	EBI-1172957,EBI-2855248
SDC3	O75056	2	EBI-1172957,EBI-1642090
SDC4	P31431	2	EBI-1172957,EBI-3913237

Show more details

GO - Molecular functionⁱ

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	112285, 91 interactors
Database of interacting proteins More...DIPⁱ	DIP-29943N
IntActⁱ	P34741, 20 interactors
Molecular INTeraction database More...MINTⁱ	P34741
STRINGⁱ	9606.ENSP00000307046

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P34741
SMRⁱ	P34741
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the syndecan proteoglycan family.Curated

Keywords - Domainⁱ

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG410IW5I Eukaryota ENOG4111QSA LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063116
HOGENOMⁱ	HOG000263414
HOVERGENⁱ	HBG004501
InParanoidⁱ	P34741
KEGG Orthology (KO) More...KOⁱ	K16336
OMAⁱ	MQRAWIL
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0OOE
PhylomeDBⁱ	P34741
TreeFamⁱ	TF320463

Family and domain databases

InterProⁱ	View protein in InterPro IPR003585 Neurexin-like IPR001050 Syndecan IPR031201 Syndecan-2 IPR027789 Syndecan/Neurexin_dom IPR030479 Syndecan_CS
PANTHERⁱ	PTHR10915 PTHR10915, 1 hit PTHR10915:SF6 PTHR10915:SF6, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01034 Syndecan, 1 hit
SMARTⁱ	View protein in SMART SM00294 4.1m, 1 hit
PROSITEⁱ	View protein in PROSITE PS00964 SYNDECAN, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P34741-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRRAWILLTL GLVACVSAES RAELTSDKDM YLDNSSIEEA SGVYPIDDDD 
        60         70         80         90        100
YASASGSGAD EDVESPELTT SRPLPKILLT SAAPKVETTT LNIQNKIPAQ 
       110        120        130        140        150
TKSPEETDKE KVHLSDSERK MDPAEEDTNV YTEKHSDSLF KRTEVLAAVI 
       160        170        180        190        200
AGGVIGFLFA IFLILLLVYR MRKKDEGSYD LGERKPSSAA YQKAPTKEFY 

A

Length:201

Mass (Da):22,160

Last modified:August 21, 2007 - v2

Checksum:ⁱ7DA4159D54741054

GO

Sequence cautionⁱ

The sequence AAA52701 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	150	I → T in BAB15150 (PubMed:14702039).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_034675	59	A → T1 PublicationCorresponds to variant dbSNP:rs3816208Ensembl.		1
Natural variantⁱVAR_034676	71	S → T2 PublicationsCorresponds to variant dbSNP:rs1042381Ensembl.		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	J04621 mRNA Translation: AAA52701.1 Different initiation. AK025488 mRNA Translation: BAB15150.1 AK074530 mRNA Translation: BAG51965.1 AK097839 mRNA Translation: BAG53540.1 CH471060 Genomic DNA Translation: EAW91755.1 BC030133 mRNA Translation: AAH30133.1 BC049836 mRNA Translation: AAH49836.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS6272.1
PIRⁱ	A33880
NCBI Reference Sequences More...RefSeqⁱ	NP_002989.2, NM_002998.3
UniGeneⁱ	Hs.1501 Hs.598247

Genome annotation databases

Ensemblⁱ	ENST00000302190; ENSP00000307046; ENSG00000169439
GeneIDⁱ	6383
KEGGⁱ	hsa:6383
UCSC genome browser More...UCSCⁱ	uc003yhv.2 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
P34741	Syndecan		HUMAN		201
Syndecan		HUMAN		172
Syndecan		HUMAN		81
Syndecan-2 (Fragment)		HUMAN		137
Syndecan-2 (Fragment)		HUMAN		145

Protein	Similar proteins		Species	Score	Length
P34741	Syndecan		HUMAN		201
UPI00048FC6D6		RABIT		220
UPI00038EFB26		CHILA		202
UPI0003C01F9E		wild yak		202
UPI000576EF3F		Bison bison bison		202
+87

Protein	Similar proteins		Species	Score	Length
P34741	Syndecan		HUMAN		201
UPI00048FC6D6		RABIT		220
UPI00046B7FF1		EPTFU		202
Syndecan		HETGA		202
UPI0002BD12BF		ORCOR		202
+109

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	J04621 mRNA Translation: AAA52701.1 Different initiation. AK025488 mRNA Translation: BAB15150.1 AK074530 mRNA Translation: BAG51965.1 AK097839 mRNA Translation: BAG53540.1 CH471060 Genomic DNA Translation: EAW91755.1 BC030133 mRNA Translation: AAH30133.1 BC049836 mRNA Translation: AAH49836.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS6272.1
PIRⁱ	A33880
NCBI Reference Sequences More...RefSeqⁱ	NP_002989.2, NM_002998.3
UniGeneⁱ	Hs.1501 Hs.598247

3D structure databases

ProteinModelPortalⁱ	P34741
SMRⁱ	P34741
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	112285, 91 interactors
Database of interacting proteins More...DIPⁱ	DIP-29943N
IntActⁱ	P34741, 20 interactors
Molecular INTeraction database More...MINTⁱ	P34741
STRINGⁱ	9606.ENSP00000307046

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB00020 Sargramostim

DrugBankⁱ

DB00020 Sargramostim

PTM databases

GlyConnectⁱ	707
iPTMnetⁱ	P34741
PhosphoSitePlusⁱ	P34741
UniCarbKBⁱ	P34741

Polymorphism and mutation databases

BioMutaⁱ	SDC2
DMDMⁱ	158962336

Proteomic databases

EPDⁱ	P34741
PaxDbⁱ	P34741
PeptideAtlas More...PeptideAtlasⁱ	P34741
PRIDEⁱ	P34741
ProteomicsDBⁱ	54941

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	6383
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000302190; ENSP00000307046; ENSG00000169439
GeneIDⁱ	6383
KEGGⁱ	hsa:6383
UCSC genome browser More...UCSCⁱ	uc003yhv.2 human

Organism-specific databases

CTDⁱ	6383
DisGeNET More...DisGeNETⁱ	6383
EuPathDBⁱ	HostDB:ENSG00000169439.11
GeneCardsⁱ	SDC2
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:10659 SDC2
Human Protein Atlas More...HPAⁱ	CAB025123 HPA044416
MIMⁱ	142460 gene
neXtProtⁱ	NX_P34741
Open Targets More...OpenTargetsⁱ	ENSG00000169439
PharmGKBⁱ	PA35589
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IW5I Eukaryota ENOG4111QSA LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063116
HOGENOMⁱ	HOG000263414
HOVERGENⁱ	HBG004501
InParanoidⁱ	P34741
KEGG Orthology (KO) More...KOⁱ	K16336
OMAⁱ	MQRAWIL
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0OOE
PhylomeDBⁱ	P34741
TreeFamⁱ	TF320463

Enzyme and pathway databases

Reactomeⁱ	R-HSA-1971475 A tetrasaccharide linker sequence is required for GAG synthesis R-HSA-2022928 HS-GAG biosynthesis R-HSA-2024096 HS-GAG degradation R-HSA-202733 Cell surface interactions at the vascular wall R-HSA-3000170 Syndecan interactions R-HSA-3560783 Defective B4GALT7 causes EDS, progeroid type R-HSA-3560801 Defective B3GAT3 causes JDSSDHD R-HSA-3656237 Defective EXT2 causes exostoses 2 R-HSA-3656253 Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-3928662 EPHB-mediated forward signaling R-HSA-4420332 Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-8957275 Post-translational protein phosphorylation R-HSA-975634 Retinoid metabolism and transport
SIGNORⁱ	P34741

Reactomeⁱ

R-HSA-1971475 A tetrasaccharide linker sequence is required for GAG synthesis
R-HSA-2022928 HS-GAG biosynthesis
R-HSA-2024096 HS-GAG degradation
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-3000170 Syndecan interactions
R-HSA-3560783 Defective B4GALT7 causes EDS, progeroid type
R-HSA-3560801 Defective B3GAT3 causes JDSSDHD
R-HSA-3656237 Defective EXT2 causes exostoses 2
R-HSA-3656253 Defective EXT1 causes exostoses 1, TRPS2 and CHDS
R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-3928662 EPHB-mediated forward signaling
R-HSA-4420332 Defective B3GALT6 causes EDSP2 and SEMDJL1
R-HSA-8957275 Post-translational protein phosphorylation
R-HSA-975634 Retinoid metabolism and transport

SIGNORⁱ

P34741

Miscellaneous databases

ChiTaRSⁱ	SDC2 human
GeneWikiⁱ	SDC2
GenomeRNAiⁱ	6383
Protein Ontology More...PROⁱ	PR:P34741
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000169439
CleanExⁱ	HS_SDC2
ExpressionAtlasⁱ	P34741 baseline and differential
Genevisibleⁱ	P34741 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR003585 Neurexin-like IPR001050 Syndecan IPR031201 Syndecan-2 IPR027789 Syndecan/Neurexin_dom IPR030479 Syndecan_CS
PANTHERⁱ	PTHR10915 PTHR10915, 1 hit PTHR10915:SF6 PTHR10915:SF6, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01034 Syndecan, 1 hit
SMARTⁱ	View protein in SMART SM00294 4.1m, 1 hit
PROSITEⁱ	View protein in PROSITE PS00964 SYNDECAN, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SDC2_HUMAN
Accessionⁱ	P34741Primary (citable) accession number: P34741 Secondary accession number(s): B3KQA3, Q6PIS6, Q9H6V1
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
	Last sequence update:	August 21, 2007
	Last modified:	June 20, 2018
	This is version 173 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human cell differentiation molecules
CD nomenclature of surface proteins of human leucocytes and list of entries
Human chromosome 8
Human chromosome 8: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
SIMILARITY comments
Index of protein domains and families

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UniProtKB - P34741 (SDC2_HUMAN)

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Syndecan-2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Endoplasmic reticulum

Extracellular region or secreted

Golgi apparatus

Lysosome

Plasma Membrane

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Sites

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ