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Protein

Protein BMH2

Gene

BMH2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 47600 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • DNA replication origin binding Source: SGD
  • phosphoserine residue binding Source: SGD
  • protein domain specific binding Source: InterPro

GO - Biological processi

Enzyme and pathway databases

BioCyciYEAST:G3O-29702-MONOMER
ReactomeiR-SCE-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-SCE-3371453 Regulation of HSF1-mediated heat shock response
R-SCE-3371511 HSF1 activation
R-SCE-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
R-SCE-5625740 RHO GTPases activate PKNs
R-SCE-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
R-SCE-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex

Names & Taxonomyi

Protein namesi
Recommended name:
Protein BMH2
Gene namesi
Name:BMH2
Ordered Locus Names:YDR099W
ORF Names:YD8557.08
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

SGDiS000002506 BMH2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000587162 – 273Protein BMH2Add BLAST272

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserine1 Publication1

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiP34730
PaxDbiP34730
PRIDEiP34730
TopDownProteomicsiP34730

2D gel databases

SWISS-2DPAGEiP34730

PTM databases

iPTMnetiP34730

Interactioni

Subunit structurei

Interacts with FIN1.1 Publication

Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

BioGridi32157, 251 interactors
DIPiDIP-1212N
IntActiP34730, 83 interactors
MINTiP34730
STRINGi4932.YDR099W

Structurei

3D structure databases

ProteinModelPortaliP34730
SMRiP34730
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi245 – 261Poly-GlnAdd BLAST17

Sequence similaritiesi

Belongs to the 14-3-3 family.Curated

Phylogenomic databases

GeneTreeiENSGT00760000119116
HOGENOMiHOG000240379
InParanoidiP34730
KOiK06630
OMAiMKEHEKG
OrthoDBiEOG092C46UY

Family and domain databases

Gene3Di1.20.190.20, 1 hit
InterProiView protein in InterPro
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain
PANTHERiPTHR18860 PTHR18860, 1 hit
PfamiView protein in Pfam
PF00244 14-3-3, 1 hit
PIRSFiPIRSF000868 14-3-3, 1 hit
PRINTSiPR00305 1433ZETA
SMARTiView protein in SMART
SM00101 14_3_3, 1 hit
SUPFAMiSSF48445 SSF48445, 1 hit
PROSITEiView protein in PROSITE
PS00796 1433_1, 1 hit
PS00797 1433_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P34730-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQTREDSVY LAKLAEQAER YEEMVENMKA VASSGQELSV EERNLLSVAY
60 70 80 90 100
KNVIGARRAS WRIVSSIEQK EESKEKSEHQ VELIRSYRSK IETELTKISD
110 120 130 140 150
DILSVLDSHL IPSATTGESK VFYYKMKGDY HRYLAEFSSG DAREKATNSS
160 170 180 190 200
LEAYKTASEI ATTELPPTHP IRLGLALNFS VFYYEIQNSP DKACHLAKQA
210 220 230 240 250
FDDAIAELDT LSEESYKDST LIMQLLRDNL TLWTSDISES GQEDQQQQQQ
260 270
QQQQQQQQQQ QAPAEQTQGE PTK
Length:273
Mass (Da):31,061
Last modified:January 23, 2007 - v3
Checksum:i74788A9103F129FB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti119S → C in CAA59275 (PubMed:7744048).Curated1
Sequence conflicti174G → F in CAA59275 (PubMed:7744048).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X84817 Genomic DNA Translation: CAA59275.1
U01883 Unassigned DNA Translation: AAA03336.1
Z47746 Genomic DNA Translation: CAA87675.1
DQ881448 mRNA Translation: ABI95875.1
EF123145 mRNA Translation: ABM97489.1
BK006938 Genomic DNA Translation: DAA11946.1
PIRiS51250
RefSeqiNP_010384.3, NM_001180407.3

Genome annotation databases

EnsemblFungiiYDR099W; YDR099W; YDR099W
GeneIDi851676
KEGGisce:YDR099W

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X84817 Genomic DNA Translation: CAA59275.1
U01883 Unassigned DNA Translation: AAA03336.1
Z47746 Genomic DNA Translation: CAA87675.1
DQ881448 mRNA Translation: ABI95875.1
EF123145 mRNA Translation: ABM97489.1
BK006938 Genomic DNA Translation: DAA11946.1
PIRiS51250
RefSeqiNP_010384.3, NM_001180407.3

3D structure databases

ProteinModelPortaliP34730
SMRiP34730
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32157, 251 interactors
DIPiDIP-1212N
IntActiP34730, 83 interactors
MINTiP34730
STRINGi4932.YDR099W

PTM databases

iPTMnetiP34730

2D gel databases

SWISS-2DPAGEiP34730

Proteomic databases

MaxQBiP34730
PaxDbiP34730
PRIDEiP34730
TopDownProteomicsiP34730

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR099W; YDR099W; YDR099W
GeneIDi851676
KEGGisce:YDR099W

Organism-specific databases

SGDiS000002506 BMH2

Phylogenomic databases

GeneTreeiENSGT00760000119116
HOGENOMiHOG000240379
InParanoidiP34730
KOiK06630
OMAiMKEHEKG
OrthoDBiEOG092C46UY

Enzyme and pathway databases

BioCyciYEAST:G3O-29702-MONOMER
ReactomeiR-SCE-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-SCE-3371453 Regulation of HSF1-mediated heat shock response
R-SCE-3371511 HSF1 activation
R-SCE-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
R-SCE-5625740 RHO GTPases activate PKNs
R-SCE-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
R-SCE-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex

Miscellaneous databases

PROiPR:P34730

Family and domain databases

Gene3Di1.20.190.20, 1 hit
InterProiView protein in InterPro
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain
PANTHERiPTHR18860 PTHR18860, 1 hit
PfamiView protein in Pfam
PF00244 14-3-3, 1 hit
PIRSFiPIRSF000868 14-3-3, 1 hit
PRINTSiPR00305 1433ZETA
SMARTiView protein in SMART
SM00101 14_3_3, 1 hit
SUPFAMiSSF48445 SSF48445, 1 hit
PROSITEiView protein in PROSITE
PS00796 1433_1, 1 hit
PS00797 1433_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiBMH2_YEAST
AccessioniPrimary (citable) accession number: P34730
Secondary accession number(s): A2TBP2, D6VS86, Q06HN5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: January 23, 2007
Last modified: November 7, 2018
This is version 175 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names
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