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Entry version 158 (02 Jun 2021)
Sequence version 2 (28 Mar 2003)
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Protein

Multidrug resistance protein pgp-1

Gene

pgp-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • ATP + H(2)O + xenobiotic(Side 1) = ADP + phosphate + xenobiotic(Side 2). EC:7.6.2.2

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi451 – 458ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1112 – 1119ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocase
Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
7.6.2.2, 1045

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-983170, Antigen Presentation: Folding, assembly and peptide loading of class I MHC

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.1.201.14, the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Multidrug resistance protein pgp-1 (EC:7.6.2.2)
Alternative name(s):
P-glycoprotein A
P-glycoprotein-related protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pgp-1
ORF Names:K08E7.9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

WormBase

More...
WormBasei
K08E7.9 ; CE11932 ; WBGene00003995 ; pgp-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 77CytoplasmicSequence analysisAdd BLAST77
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei78 – 98HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei144 – 164HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei213 – 233HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei240 – 260HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei321 – 341HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei350 – 370HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini371 – 753CytoplasmicSequence analysisAdd BLAST383
Transmembranei754 – 774HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei798 – 818HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei874 – 894HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei895 – 915HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei978 – 998HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei1017 – 1037HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini1038 – 1321CytoplasmicSequence analysisAdd BLAST284

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000933421 – 1321Multidrug resistance protein pgp-1Add BLAST1321

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi115N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi125N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi190N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi850N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P34712

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P34712

PeptideAtlas

More...
PeptideAtlasi
P34712

PRoteomics IDEntifications database

More...
PRIDEi
P34712

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P34712

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Intestinal cells.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00003995, Expressed in multi-cellular organism and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.K08E7.9

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11321
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P34712

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini77 – 381ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST305
Domaini416 – 652ABC transporter 1PROSITE-ProRule annotationAdd BLAST237
Domaini754 – 1043ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST290
Domaini1077 – 1315ABC transporter 2PROSITE-ProRule annotationAdd BLAST239

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0055, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00970000195996

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000604_17_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P34712

Identification of Orthologs from Complete Genome Data

More...
OMAi
NKCEASK

Database of Orthologous Groups

More...
OrthoDBi
186078at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P34712

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1560.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR011527, ABC1_TM_dom
IPR036640, ABC1_TM_sf
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR027417, P-loop_NTPase
IPR039421, Type_1_exporter

The PANTHER Classification System

More...
PANTHERi
PTHR24221, PTHR24221, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00664, ABC_membrane, 2 hits
PF00005, ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits
SSF90123, SSF90123, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50929, ABC_TM1F, 2 hits
PS00211, ABC_TRANSPORTER_1, 2 hits
PS50893, ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P34712-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRNGSLRQS LRTLDSFSLA PEDVLKTAIK TVEDYEGDNI DSNGEIKITR
60 70 80 90 100
DAKEEVVNKV SIPQLYRYTT TLEKLLLFIG TLVAVITGAG LPLMSILQGK
110 120 130 140 150
VSQAFINEQI VINNNGSTFL PTGQNYTKTD FEHDVMNVVW SYAAMTVGMW
160 170 180 190 200
AAGQITVTCY LYVAEQMNNR LRREFVKSIL RQEISWFDTN HSGTLATKLF
210 220 230 240 250
DNLERVKEGT GDKIGMAFQY LSQFITGFIV AFTHSWQLTL VMLAVTPIQA
260 270 280 290 300
LCGFAIAKSM STFAIRETLR YAKAGKVVEE TISSIRTVVS LNGLRYELER
310 320 330 340 350
YSTAVEEAKK AGVLKGLFLG ISFGAMQASN FISFALAFYI GVGWVHDGSL
360 370 380 390 400
NFGDMLTTFS SVMMGSMALG LAGPQLAVLG TAQGAASGIY EVLDRKPVID
410 420 430 440 450
SSSKAGRKDM KIKGDITVEN VHFTYPSRPD VPILRGMNLR VNAGQTVALV
460 470 480 490 500
GSSGCGKSTI ISLLLRYYDV LKGKITIDGV DVRDINLEFL RKNVAVVSQE
510 520 530 540 550
PALFNCTIEE NISLGKEGIT REEMVAACKM ANAEKFIKTL PNGYNTLVGD
560 570 580 590 600
RGTQLSGGQK QRIAIARALV RNPKILLLDE ATSALDAESE GIVQQALDKA
610 620 630 640 650
AKGRTTIIIA HRLSTIRNAD LIISCKNGQV VEVGDHRALM AQQGLYYDLV
660 670 680 690 700
TAQTFTDAVD SAAEGKFSRE NSVARQTSEH EGLSRQASEM DDIMNRVRSS
710 720 730 740 750
TIGSITNGPV IDEKEERIGK DALSRLKQEL EENNAQKTNL FEILYHARPH
760 770 780 790 800
ALSLFIGMST ATIGGFIYPT YSVFFTSFMN VFAGNPADFL SQGHFWALMF
810 820 830 840 850
LVLAAAQGIC SFLMTFFMGI ASESLTRDLR NKLFRNVLSQ HIGFFDSPQN
860 870 880 890 900
ASGKISTRLA TDVPNLRTAI DFRFSTVITT LVSMVAGIGL AFFYGWQMAL
910 920 930 940 950
LIIAILPIVA FGQYLRGRRF TGKNVKSASE FADSGKIAIE AIENVRTVQA
960 970 980 990 1000
LAREDTFYEN FCEKLDIPHK EAIKEAFIQG LSYGCASSVL YLLNTCAYRM
1010 1020 1030 1040 1050
GLALIITDPP TMQPMRVLRV MYAITISTST LGFATSYFPE YAKATFAGGI
1060 1070 1080 1090 1100
IFGMLRKISK IDSLSLAGEK KKLYGKVIFK NVRFAYPERP EIEILKGLSF
1110 1120 1130 1140 1150
SVEPGQTLAL VGPSGCGKST VVALLERFYD TLGGEIFIDG SEIKTLNPEH
1160 1170 1180 1190 1200
TRSQIAIVSQ EPTLFDCSIA ENIIYGLDPS SVTMAQVEEA ARLANIHNFI
1210 1220 1230 1240 1250
AELPEGFETR VGDRGTQLSG GQKQRIAIAR ALVRNPKILL LDEATSALDT
1260 1270 1280 1290 1300
ESEKVVQEAL DRAREGRTCI VIAHRLNTVM NADCIAVVSN GTIIEKGTHT
1310 1320
QLMSEKGAYY KLTQKQMTEK K
Length:1,321
Mass (Da):145,063
Last modified:March 28, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i68094121B30E8746
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti156T → I in CAA46190 (PubMed:1360540).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X65054 Genomic DNA Translation: CAA46190.1
Z77666 Genomic DNA Translation: CAB01232.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S27337
T23476

NCBI Reference Sequences

More...
RefSeqi
NP_502413.1, NM_070012.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
K08E7.9.1; K08E7.9.1; WBGene00003995

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
178215

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_K08E7.9

UCSC genome browser

More...
UCSCi
K08E7.9, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X65054 Genomic DNA Translation: CAA46190.1
Z77666 Genomic DNA Translation: CAB01232.1
PIRiS27337
T23476
RefSeqiNP_502413.1, NM_070012.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4F4CX-ray3.40A1-1321[»]
SMRiP34712
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi6239.K08E7.9

Protein family/group databases

TCDBi3.A.1.201.14, the atp-binding cassette (abc) superfamily

PTM databases

iPTMnetiP34712

Proteomic databases

EPDiP34712
PaxDbiP34712
PeptideAtlasiP34712
PRIDEiP34712

Genome annotation databases

EnsemblMetazoaiK08E7.9.1; K08E7.9.1; WBGene00003995
GeneIDi178215
KEGGicel:CELE_K08E7.9
UCSCiK08E7.9, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
178215
WormBaseiK08E7.9 ; CE11932 ; WBGene00003995 ; pgp-1

Phylogenomic databases

eggNOGiKOG0055, Eukaryota
GeneTreeiENSGT00970000195996
HOGENOMiCLU_000604_17_2_1
InParanoidiP34712
OMAiNKCEASK
OrthoDBi186078at2759
PhylomeDBiP34712

Enzyme and pathway databases

BRENDAi7.6.2.2, 1045
ReactomeiR-CEL-983170, Antigen Presentation: Folding, assembly and peptide loading of class I MHC

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P34712

Gene expression databases

BgeeiWBGene00003995, Expressed in multi-cellular organism and 4 other tissues

Family and domain databases

Gene3Di1.20.1560.10, 3 hits
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR011527, ABC1_TM_dom
IPR036640, ABC1_TM_sf
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR027417, P-loop_NTPase
IPR039421, Type_1_exporter
PANTHERiPTHR24221, PTHR24221, 1 hit
PfamiView protein in Pfam
PF00664, ABC_membrane, 2 hits
PF00005, ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SUPFAMiSSF52540, SSF52540, 2 hits
SSF90123, SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929, ABC_TM1F, 2 hits
PS00211, ABC_TRANSPORTER_1, 2 hits
PS50893, ABC_TRANSPORTER_2, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPGP1_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P34712
Secondary accession number(s): Q21349
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: March 28, 2003
Last modified: June 2, 2021
This is version 158 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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