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Entry version 149 (26 Feb 2020)
Sequence version 1 (01 Feb 1994)
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Protein

Probable clathrin heavy chain 1

Gene

chc-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). May play a role in yolk protein clatherin-mediated endocytosis by oocytes during oogenesis (PubMed:19798448).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-190873 Gap junction degradation
R-CEL-196025 Formation of annular gap junctions
R-CEL-432720 Lysosome Vesicle Biogenesis
R-CEL-432722 Golgi Associated Vesicle Biogenesis
R-CEL-437239 Recycling pathway of L1
R-CEL-5099900 WNT5A-dependent internalization of FZD4
R-CEL-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2
R-CEL-8856825 Cargo recognition for clathrin-mediated endocytosis
R-CEL-8856828 Clathrin-mediated endocytosis
R-CEL-8866427 VLDLR internalisation and degradation
R-CEL-8964038 LDL clearance

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable clathrin heavy chain 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:chc-1
ORF Names:T20G5.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

WormBase

More...
WormBasei
T20G5.1 ; CE00480 ; WBGene00011867 ; chc-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Coated pit, Cytoplasmic vesicle, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

RNAi-mediated knockdown results in defective endocytosis by oocytes characterized by an accumulation of aggregated yolk protein in the pseudocoelomatic space.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002057811 – 1681Probable clathrin heavy chain 1Add BLAST1681

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P34574

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P34574

PeptideAtlas

More...
PeptideAtlasi
P34574

PRoteomics IDEntifications database

More...
PRIDEi
P34574

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00011867 Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Clathrin triskelions, composed of 3 heavy chains and 3 light chains, are the basic subunits of the clathrin coat (By similarity). May interact with beta arrestin arr-1 (PubMed:15878875).

By similarity1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
41628, 36 interactors

Database of interacting proteins

More...
DIPi
DIP-25251N

Protein interaction database and analysis system

More...
IntActi
P34574, 20 interactors

Molecular INTeraction database

More...
MINTi
P34574

STRING: functional protein association networks

More...
STRINGi
6239.T20G5.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P34574

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati539 – 685CHCR 1Add BLAST147
Repeati688 – 830CHCR 2Add BLAST143
Repeati835 – 974CHCR 3Add BLAST140
Repeati981 – 1126CHCR 4Add BLAST146
Repeati1130 – 1271CHCR 5Add BLAST142
Repeati1276 – 1422CHCR 6Add BLAST147
Repeati1425 – 1568CHCR 7Add BLAST144

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni22 – 65WD40-like repeat 1Add BLAST44
Regioni66 – 105WD40-like repeat 2Add BLAST40
Regioni106 – 147WD40-like repeat 3Add BLAST42
Regioni148 – 193WD40-like repeat 4Add BLAST46
Regioni194 – 255WD40-like repeat 5Add BLAST62
Regioni256 – 299WD40-like repeat 6Add BLAST44
Regioni300 – 328WD40-like repeat 7Add BLAST29

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The C-terminal third of the heavy chains forms the hub of the triskelion. This region contains the trimerization domain and the light-chain binding domain involved in the assembly of the clathrin lattice.
The N-terminal seven-bladed beta-propeller is formed by WD40-like repeats, and projects inward from the polyhedral outer clathrin coat. It constitutes a major protein-protein interaction node (By similarity).By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the clathrin heavy chain family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0985 Eukaryota
ENOG410XPH1 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183166

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002136_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P34574

KEGG Orthology (KO)

More...
KOi
K04646

Identification of Orthologs from Complete Genome Data

More...
OMAi
NLMSAPQ

Database of Orthologous Groups

More...
OrthoDBi
17940at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P34574

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 4 hits
2.130.10.110, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR000547 Clathrin_H-chain/VPS_repeat
IPR015348 Clathrin_H-chain_linker_core
IPR016025 Clathrin_H-chain_N
IPR022365 Clathrin_H-chain_propeller_rpt
IPR016341 Clathrin_heavy_chain
IPR011990 TPR-like_helical_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00637 Clathrin, 7 hits
PF09268 Clathrin-link, 1 hit
PF01394 Clathrin_propel, 4 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002290 Clathrin_H_chain, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00299 CLH, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 6 hits
SSF50989 SSF50989, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50236 CHCR, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P34574-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALPIKFHEH LQLPNAGIRV PNITFSNVTM ESDKNIVVRE MIGDQQQVVI
60 70 80 90 100
IDLADTANPT RRPISADSVI MHPTAKILAL KSGKTLQIFN IELKAKVKAH
110 120 130 140 150
QNVEDVVYWK WISEKTIALV SDTAVYHWSI EGDAAPVKMF DRHQSLAGTQ
160 170 180 190 200
IINYRADAEN KWLVLIGISA KDSRVVGSMQ LYSTERKVSQ PIEGHAACFV
210 220 230 240 250
RFKVDGNQNP SNLFCFSVKT DNGGKLHVIE VGTPAAGNTP FQKKNVDVPY
260 270 280 290 300
TADTAGDFPV SMQVSAKQGI IYLVTKQGYV HLYDVESGTR IYSNRISTDT
310 320 330 340 350
VFVTCEYTAT GGIMGINRKG QVLSVSIDEA NLVPFVTNQL QNPDLALKLA
360 370 380 390 400
VRCDLPGAEE LFVRKFNLLF SNGQFGESAK VAASAPQGIL RTPATIQKFQ
410 420 430 440 450
QCPSTGPGPS PLLQYFGILL DQGKLNKYET LELCRPVLAQ GRKELITKWL
460 470 480 490 500
NDQKLECCEE LGDLIKPHDV NTALSVYLRG NVPHKVVQSF AETGQFDKIV
510 520 530 540 550
MYAKRVGFQP DYLFQLRQIL RNSNPDHGAK FAQLLVSESE NGEPLADLSQ
560 570 580 590 600
IIDCFMEVQA VQPCTSFLLE VLKGDKPEEG HLQTRLLEMN LLAAPAVADA
610 620 630 640 650
ILANKMFSHY DRAAIGQLCE KAGLLQRALE HFTDLYDIKR TVVHTHLLKP
660 670 680 690 700
DWLVGYFGSL SVEDSVECLK AMLTQNIRQN LQVVVQIASK YHEQLGADKL
710 720 730 740 750
IEMFENHKSY EGLFYFLGSI VNFSQDPEVH FKYIQAATRT GQIKEVERIC
760 770 780 790 800
RESQCYDAER VKNFLKEAKL NDQLPLIIVC DRHNMVHDLV LYLYRNQLQK
810 820 830 840 850
YIEVFVQKVN AARLPIVVGA LLDVDCSEDA IKQLIINTRG KFDIDELVEE
860 870 880 890 900
VEKRNRLKLL NHWLESKIQE GATDAATHNA MAKIYIDSNN NPERFLKENP
910 920 930 940 950
YYDSKVVGKY CEKRDPHYAF LSYERGQCDA ELINVCNENS LFKNLARYLV
960 970 980 990 1000
KRRDFTLWEQ VLNEENVHRR QLIDQVVQTA LSETQDPEDI SVTVKAFMAA
1010 1020 1030 1040 1050
DLPNELIELL EKIVLDNSAF SEHRNLQNLL ILTAMRADRT RVMEYIQKLD
1060 1070 1080 1090 1100
NYDAPDIANI AITSELYEEA FAIFKKFDVN SSAINVLIEN VNNLDRAYEF
1110 1120 1130 1140 1150
AEKCNQSDVW ASLAKAQLQQ NLVKEAVDSF IKADDPGAYM EVVNKCSQTE
1160 1170 1180 1190 1200
HWEDLVRYLQ MARKKSRESY IETELVFALA KTGRLTELEE FIAGPNHAQI
1210 1220 1230 1240 1250
GQIGDRCFDN GMFDSAKILF NNVSNFAKLS VTLVRLGEYQ GAVDAARKAN
1260 1270 1280 1290 1300
STKTWKQVCF SCVENGEFRL AQMCGLHIVV HADELEELIN FYQDRGHFEE
1310 1320 1330 1340 1350
LIALLEAALG LERAHMGMFT ELAILYSKYK PEKMREHLEL FWSRVNIPKV
1360 1370 1380 1390 1400
LRAAEQAHLW SELVFLYDKY EEYDNAALTM MQHPTESWRE QHFKEVIAKV
1410 1420 1430 1440 1450
ANVELYYKAM QFYLDYKPLL LNDLLTVLSP RLDHSRTVLF FNKLKQIPLV
1460 1470 1480 1490 1500
KPYLRQVQNL NNKAINEALN QLLIDEEDHA GLRSSIEAQD NFDNITLAQQ
1510 1520 1530 1540 1550
LEKHPLVEFR RISAYLFKGN NRWKQSIELC KKDKLYKDAM EYAAESRNGE
1560 1570 1580 1590 1600
LAEELLSFFL DEKLYDCFAA SLYHCYDLLH PDVIMELAWK HKIMDYAMPY
1610 1620 1630 1640 1650
MIQVMRDYQT RLEKLERSEH ERKEEKAEQQ QNNGMTMEPQ LMLTYGAPAP
1660 1670 1680
QMTYPGTTGG YGGQPAYGQP GQPGYNAPGF M
Length:1,681
Mass (Da):191,542
Last modified:February 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44D15C61339009D9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z30423 Genomic DNA Translation: CAA83003.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S42369

NCBI Reference Sequences

More...
RefSeqi
NP_499260.1, NM_066859.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
T20G5.1.1; T20G5.1.1; WBGene00011867

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
176434

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_T20G5.1

UCSC genome browser

More...
UCSCi
T20G5.1 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z30423 Genomic DNA Translation: CAA83003.1
PIRiS42369
RefSeqiNP_499260.1, NM_066859.4

3D structure databases

SMRiP34574
ModBaseiSearch...

Protein-protein interaction databases

BioGridi41628, 36 interactors
DIPiDIP-25251N
IntActiP34574, 20 interactors
MINTiP34574
STRINGi6239.T20G5.1

Proteomic databases

EPDiP34574
PaxDbiP34574
PeptideAtlasiP34574
PRIDEiP34574

Genome annotation databases

EnsemblMetazoaiT20G5.1.1; T20G5.1.1; WBGene00011867
GeneIDi176434
KEGGicel:CELE_T20G5.1
UCSCiT20G5.1 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
176434
WormBaseiT20G5.1 ; CE00480 ; WBGene00011867 ; chc-1

Phylogenomic databases

eggNOGiKOG0985 Eukaryota
ENOG410XPH1 LUCA
GeneTreeiENSGT00950000183166
HOGENOMiCLU_002136_0_0_1
InParanoidiP34574
KOiK04646
OMAiNLMSAPQ
OrthoDBi17940at2759
PhylomeDBiP34574

Enzyme and pathway databases

ReactomeiR-CEL-190873 Gap junction degradation
R-CEL-196025 Formation of annular gap junctions
R-CEL-432720 Lysosome Vesicle Biogenesis
R-CEL-432722 Golgi Associated Vesicle Biogenesis
R-CEL-437239 Recycling pathway of L1
R-CEL-5099900 WNT5A-dependent internalization of FZD4
R-CEL-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2
R-CEL-8856825 Cargo recognition for clathrin-mediated endocytosis
R-CEL-8856828 Clathrin-mediated endocytosis
R-CEL-8866427 VLDLR internalisation and degradation
R-CEL-8964038 LDL clearance

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P34574

Gene expression databases

BgeeiWBGene00011867 Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues

Family and domain databases

Gene3Di1.25.40.10, 4 hits
2.130.10.110, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR000547 Clathrin_H-chain/VPS_repeat
IPR015348 Clathrin_H-chain_linker_core
IPR016025 Clathrin_H-chain_N
IPR022365 Clathrin_H-chain_propeller_rpt
IPR016341 Clathrin_heavy_chain
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF00637 Clathrin, 7 hits
PF09268 Clathrin-link, 1 hit
PF01394 Clathrin_propel, 4 hits
PIRSFiPIRSF002290 Clathrin_H_chain, 1 hit
SMARTiView protein in SMART
SM00299 CLH, 7 hits
SUPFAMiSSF48371 SSF48371, 6 hits
SSF50989 SSF50989, 1 hit
PROSITEiView protein in PROSITE
PS50236 CHCR, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCLH_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P34574
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: February 26, 2020
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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