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Entry version 117 (18 Sep 2019)
Sequence version 2 (06 Jun 2002)
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Protein

Putative protein tag-250

Gene

tag-250

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative protein tag-250
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tag-250
ORF Names:C29E4.5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

WormBase

More...
WormBasei
C29E4.5a ; CE43801 ; WBGene00016203 ; tag-250
C29E4.5b ; CE43781 ; WBGene00016203 ; tag-250

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001831841 – 610Putative protein tag-250Add BLAST610

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
P34344

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P34344

PeptideAtlas

More...
PeptideAtlasi
P34344

PRoteomics IDEntifications database

More...
PRIDEi
P34344

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00016203 Expressed in 5 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
CELE_W09D6.5Q9XUJ24EBI-2414102,EBI-2414107

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
P34344, 2 interactors

STRING: functional protein association networks

More...
STRINGi
6239.C29E4.5a

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P34344

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini149 – 260Tudor 1Add BLAST112
Domaini386 – 506Tudor 2Add BLAST121

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410K8TC Eukaryota
ENOG4110K1H LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P34344

Database of Orthologous Groups

More...
OrthoDBi
367599at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR002999 Tudor

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00567 TUDOR, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00333 TUDOR, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform a (identifier: P34344-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSAVNGLVPS TIFDRINSDM DVSEEMEEIR EVLYEMIKTN FPMGVAATHL
60 70 80 90 100
SEKYHEEFVS KGLGRELPED WIQQVTAAEE FEAQTRGPIT ILFVRLSNTS
110 120 130 140 150
SFKRPPINSV NVRVISTDRE PTADELKKIK QRKENEPTEH AKTLSQQSVA
160 170 180 190 200
LKEGSTVSIV YADSPKRFFI RALADDDQYE KIGTTLAEIY AQETPPSALD
210 220 230 240 250
SRVAIYEIVA GGAYALQDSN GTWFRVIAKQ PPQSGQVMCH FVDVGVCEKF
260 270 280 290 300
PVAAIRLLPP AVHPVMSIGS MAREVRMDVS EEESLRLNNK FVDLTFETKD
310 320 330 340 350
DGIQVPINLT LSKFDSSDSE SLPVVDLQSS DGLSITEFLK KPSGVVRLST
360 370 380 390 400
PTKTTSPITP ASASTSSLTC LFDKPATIQP MTVAQMPMSA FPANAIFAAG
410 420 430 440 450
PTDISLRQLS LDPMPDYMYA KLKDECALPD SQLESSPDFG GFYAAFIDDR
460 470 480 490 500
WERVQCIRAS KIDKQAYCVY LLDVGAFQYV RKEAMRRLNS TSPFKKMLMF
510 520 530 540 550
KCKIGGIKPV AGGEVWSRES HEAVREFFEA ACGEPVVVEP TQPGWSQWKQ
560 570 580 590 600
LNAPAVPTCE ARLSCCGRDI GDWLIACGLA LPINAPIPSP NSQSLLTFVP
610
TPINIVGRNI
Note: No experimental confirmation available.
Length:610
Mass (Da):67,333
Last modified:June 6, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2E5F0412B52BC544
GO
Isoform b (identifier: P34344-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     114-136: VISTDREPTADELKKIKQRKENE → ACPIRINTTPPLSSLTLIRIWRN
     137-610: Missing.

Note: No experimental confirmation available.
Show »
Length:136
Mass (Da):15,467
Checksum:i4DE2390066766F5F
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CCD66014 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CCD66015 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_015953114 – 136VISTD…RKENE → ACPIRINTTPPLSSLTLIRI WRN in isoform b. CuratedAdd BLAST23
Alternative sequenceiVSP_015954137 – 610Missing in isoform b. CuratedAdd BLAST474

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FO080706 Genomic DNA Translation: CCD66014.1 Sequence problems.
FO080706 Genomic DNA Translation: CCD66015.1 Sequence problems.

Protein sequence database of the Protein Information Resource

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PIRi
S44773

NCBI Reference Sequences

More...
RefSeqi
NP_001021188.2, NM_001026017.3
NP_001021189.2, NM_001026018.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C29E4.5a.1; C29E4.5a.1; WBGene00016203
C29E4.5b.1; C29E4.5b.1; WBGene00016203

Database of genes from NCBI RefSeq genomes

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GeneIDi
176113

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_C29E4.5

UCSC genome browser

More...
UCSCi
C29E4.5a c. elegans [P34344-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080706 Genomic DNA Translation: CCD66014.1 Sequence problems.
FO080706 Genomic DNA Translation: CCD66015.1 Sequence problems.
PIRiS44773
RefSeqiNP_001021188.2, NM_001026017.3
NP_001021189.2, NM_001026018.2

3D structure databases

SMRiP34344
ModBaseiSearch...

Protein-protein interaction databases

IntActiP34344, 2 interactors
STRINGi6239.C29E4.5a

Proteomic databases

EPDiP34344
PaxDbiP34344
PeptideAtlasiP34344
PRIDEiP34344

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC29E4.5a.1; C29E4.5a.1; WBGene00016203
C29E4.5b.1; C29E4.5b.1; WBGene00016203
GeneIDi176113
KEGGicel:CELE_C29E4.5
UCSCiC29E4.5a c. elegans [P34344-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
176113
WormBaseiC29E4.5a ; CE43801 ; WBGene00016203 ; tag-250
C29E4.5b ; CE43781 ; WBGene00016203 ; tag-250

Phylogenomic databases

eggNOGiENOG410K8TC Eukaryota
ENOG4110K1H LUCA
InParanoidiP34344
OrthoDBi367599at2759

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P34344

Gene expression databases

BgeeiWBGene00016203 Expressed in 5 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

Family and domain databases

InterProiView protein in InterPro
IPR002999 Tudor
PfamiView protein in Pfam
PF00567 TUDOR, 2 hits
SMARTiView protein in SMART
SM00333 TUDOR, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTG250_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P34344
Secondary accession number(s): C8JQN7, Q4TTD4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: June 6, 2002
Last modified: September 18, 2019
This is version 117 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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