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Protein

Outer membrane protease OmpP

Gene

ompP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Protease; also acts as a receptor for bacteriophage Ox2.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei103By similarity1
Active sitei105By similarity1
Active sitei230By similarity1
Active sitei232By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl protease, Hydrolase, Protease

Enzyme and pathway databases

BRENDAi3.4.23.49 2026

Protein family/group databases

MEROPSiA26.002
TCDBi9.B.50.1.2 the outer membrane beta-barrel endoprotease, omptin (omptin) family

Names & Taxonomyi

Protein namesi
Recommended name:
Outer membrane protease OmpP (EC:3.4.23.-)
Gene namesi
Name:ompP
Synonyms:ompX
Ordered Locus Names:ECOK12F029
Encoded oniPlasmid F0 Publication
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 231 PublicationAdd BLAST23
ChainiPRO_000002581724 – 315Outer membrane protease OmpPAdd BLAST292

Proteomic databases

PRIDEiP34210

Structurei

3D structure databases

ProteinModelPortaliP34210
SMRiP34210
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase A26 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Family and domain databases

InterProiView protein in InterPro
IPR020080 OM_adhesin/peptidase_omptin
IPR020079 Peptidase_A26_CS
IPR000036 Peptidase_A26_omptin
PfamiView protein in Pfam
PF01278 Omptin, 1 hit
PIRSFiPIRSF001522 Peptidase_A26, 1 hit
PRINTSiPR00482 OMPTIN
SUPFAMiSSF69917 SSF69917, 1 hit
PROSITEiView protein in PROSITE
PS00834 OMPTIN_1, 1 hit
PS00835 OMPTIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P34210-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQTKLLAIML AAPVVFSSQE ASASDFFGPE KISTEINLGT LSGKTKERVY
60 70 80 90 100
EPEEGGRKVS QLDWKYSNAA ILKGAVNWEL NPWLSVGAAG WTTLNSRGGN
110 120 130 140 150
MVDQDWMDSG TPGTWTDESR HPDTRLNYAN EFDLNVKGWF LKESDYRLAI
160 170 180 190 200
MAGYQESRYS FNATGGTYIY SENGGFRNET GALPDKIKVI GYKQHFKIPY
210 220 230 240 250
VGLTGNYRYD NFEFGGAFKY SGWVRGSDND EHYVRQTTFR SKVINQNYYS
260 270 280 290 300
VAVNAGYYIT PEAKVYIEGV WSRLTNKKGD TSLYDRSDNT SEHNNNGAGI
310
ENYNFITTAG LKYTF
Length:315
Mass (Da):35,499
Last modified:November 1, 1995 - v2
Checksum:i45595973C6B2B149
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X74278 Genomic DNA Translation: CAA52338.1
AP001918 Genomic DNA Translation: BAA97899.1
PIRiA36944
RefSeqiNP_061408.1, NC_002483.1
WP_001193612.1, NC_002483.1

Genome annotation databases

GeneIDi1263511

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X74278 Genomic DNA Translation: CAA52338.1
AP001918 Genomic DNA Translation: BAA97899.1
PIRiA36944
RefSeqiNP_061408.1, NC_002483.1
WP_001193612.1, NC_002483.1

3D structure databases

ProteinModelPortaliP34210
SMRiP34210
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiA26.002
TCDBi9.B.50.1.2 the outer membrane beta-barrel endoprotease, omptin (omptin) family

Proteomic databases

PRIDEiP34210

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1263511

Enzyme and pathway databases

BRENDAi3.4.23.49 2026

Miscellaneous databases

PROiPR:P34210

Family and domain databases

InterProiView protein in InterPro
IPR020080 OM_adhesin/peptidase_omptin
IPR020079 Peptidase_A26_CS
IPR000036 Peptidase_A26_omptin
PfamiView protein in Pfam
PF01278 Omptin, 1 hit
PIRSFiPIRSF001522 Peptidase_A26, 1 hit
PRINTSiPR00482 OMPTIN
SUPFAMiSSF69917 SSF69917, 1 hit
PROSITEiView protein in PROSITE
PS00834 OMPTIN_1, 1 hit
PS00835 OMPTIN_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiOMPP_ECOLI
AccessioniPrimary (citable) accession number: P34210
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: November 1, 1995
Last modified: November 7, 2018
This is version 104 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Plasmid

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Peptidase families
    Classification of peptidase families and list of entries
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Main funding by: National Institutes of Health

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