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UniProtKB - P33913 (YEJA_ECOLI)

Entry version 132 (17 Jun 2020)
Sequence version 3 (15 Dec 1998)
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Protein

Uncharacterized protein YejA

Gene

yejA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:YEJA-MONOMER
ECOL316407:JW2165-MONOMER
MetaCyc:YEJA-MONOMER

Protein family/group databases

Transport Classification Database

More...TCDBi		3.A.1.5.21 the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein YejA
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yejA
Ordered Locus Names:b2177, JW2165
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Complete GO annotation on QuickGO ...

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001387420 – 604Uncharacterized protein YejAAdd BLAST585

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P33913

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P33913

PRoteomics IDEntifications database

More...PRIDEi		P33913

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4261094, 16 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-4362 Peptide ABC transporter complex

Protein interaction database and analysis system

More...IntActi		P33913, 2 interactors

STRING: functional protein association networks

More...STRINGi		511145.b2177

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P33913

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

To H.influenzae HbpA.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG4105E43 Bacteria
COG4166 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_023171_0_0_6

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P33913

KEGG Orthology (KO)

More...KOi		K13893

Database for complete collections of gene phylogenies

More...PhylomeDBi		P33913

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR030678 Peptide/Ni-bd
IPR039424 SBP_5
IPR000914 SBP_5_dom

The PANTHER Classification System

More...PANTHERi		PTHR30290 PTHR30290, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00496 SBP_bac_5, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF002741 MppA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P33913-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIVRILLLFI ALFTFGVQAQ AIKESYAFAV LGEPRYAFNF NHFDYVNPAA 
        60         70         80         90        100
PKGGQITLSA LGTFDNFNRY ALRGNPGART EQLYDTLFTT SDDEPGSYYP 
       110        120        130        140        150
LIAESARYAD DYSWVEVAIN PRARFHDGSP ITARDVEFTF QKFMTEGVPQ 
       160        170        180        190        200
FRLVYKGTTV KAIAPLTVRI ELAKPGKEDM LSLFSLPVFP EKYWKDHKLS 
       210        220        230        240        250
DPLATPPLAS GPYRVTSWKM GQNIVYSRVK DYWAANLPVN RGRWNFDTIR 
       260        270        280        290        300
YDYYLDDNVA FEAFKAGAFD LRMENDAKNW ATRYTGKNFD KKYIIKDEQK 
       310        320        330        340        350
NESAQDTRWL AFNIQRPVFS DRRVREAITL AFDFEWMNKA LFYNAWSRTN 
       360        370        380        390        400
SYFQNTEYAA RNYPDAAELV LLAPMKKDLP SEVFTQIYQP PVSKGDGYDR 
       410        420        430        440        450
DNLLKADKLL NEAGWVLKGQ QRVNATTGQP LSFELLLPAS SNSQWVLPFQ 
       460        470        480        490        500
HSLQRLGINM DIRKVDNSQI TNRMRSRDYD MMPRVWRAMP WPSSDLQISW 
       510        520        530        540        550
SSEYINSTYN APGVQSPVID SLINQIIAAQ GNKEKLLPLG RALDRVLTWN 
       560        570        580        590        600
YYMLPMWYMA EDRLAWWDKF SQPAVRPIYS LGIDTWWYDV NKAAKLPSAS 

KQGE
Length:604
Mass (Da):69,669
Last modified:December 15, 1998 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE3D45FAF94F16B47
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti415W → G in AAA16375 (Ref. 3) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75238.2
AP009048 Genomic DNA Translation: BAA15985.2
U00008 Genomic DNA Translation: AAA16375.1

Protein sequence database of the Protein Information Resource

More...PIRi		H64986

NCBI Reference Sequences

More...RefSeqi		NP_416682.4, NC_000913.3
WP_000637046.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC75238; AAC75238; b2177
BAA15985; BAA15985; BAA15985

Database of genes from NCBI RefSeq genomes

More...GeneIDi		946675

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW2165
eco:b2177

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.59

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC75238.2
AP009048 Genomic DNA Translation: BAA15985.2
U00008 Genomic DNA Translation: AAA16375.1
PIRiH64986
RefSeqiNP_416682.4, NC_000913.3
WP_000637046.1, NZ_LN832404.1

3D structure databases

SMRiP33913
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi4261094, 16 interactors
ComplexPortaliCPX-4362 Peptide ABC transporter complex
IntActiP33913, 2 interactors
STRINGi511145.b2177

Protein family/group databases

TCDBi3.A.1.5.21 the atp-binding cassette (abc) superfamily

Proteomic databases

jPOSTiP33913
PaxDbiP33913
PRIDEiP33913

Genome annotation databases

EnsemblBacteriaiAAC75238; AAC75238; b2177
BAA15985; BAA15985; BAA15985
GeneIDi946675
KEGGiecj:JW2165
eco:b2177
PATRICifig|1411691.4.peg.59

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB1972

Phylogenomic databases

eggNOGiENOG4105E43 Bacteria
COG4166 LUCA
HOGENOMiCLU_023171_0_0_6
InParanoidiP33913
KOiK13893
PhylomeDBiP33913

Enzyme and pathway databases

BioCyciEcoCyc:YEJA-MONOMER
ECOL316407:JW2165-MONOMER
MetaCyc:YEJA-MONOMER

Miscellaneous databases

Protein Ontology

More...PROi		PR:P33913

Family and domain databases

InterProiView protein in InterPro
IPR030678 Peptide/Ni-bd
IPR039424 SBP_5
IPR000914 SBP_5_dom
PANTHERiPTHR30290 PTHR30290, 1 hit
PfamiView protein in Pfam
PF00496 SBP_bac_5, 1 hit
PIRSFiPIRSF002741 MppA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYEJA_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P33913
Secondary accession number(s): P76447
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: December 15, 1998
Last modified: June 17, 2020
This is version 132 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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