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Entry version 155 (08 May 2019)
Sequence version 3 (27 Jul 2011)
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Protein

Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

Gene

PET112

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).UniRule annotation1 Publication

Miscellaneous

Present with 1390 molecules/cell in log phase SD medium.1 Publication
This protein may be expected to contain an N-terminal transit peptide but none has been predicted.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLigase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:G3O-28971-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrialUniRule annotation (EC:6.3.5.-UniRule annotation)
Short name:
Glu-AdT subunit BUniRule annotation
Alternative name(s):
Cytochrome c oxidase assembly factor PET112
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PET112UniRule annotation
Ordered Locus Names:YBL080C
ORF Names:YBL0724
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:YBL080C

Saccharomyces Genome Database

More...
SGDi
S000000176 PET112

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000107121 – 541Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrialAdd BLAST541

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P33893

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P33893

PRoteomics IDEntifications database

More...
PRIDEi
P33893

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A (HER2), B (PET112) and F (YGR102C) subunits.

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
32623, 58 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-416 Glutamyl-tRNA(Gln) amidotransferase complex

Database of interacting proteins

More...
DIPi
DIP-5011N

Protein interaction database and analysis system

More...
IntActi
P33893, 4 interactors

STRING: functional protein association networks

More...
STRINGi
4932.YBL080C

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1541
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P33893

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GatB/GatE family. GatB subfamily.UniRule annotation

Keywords - Domaini

Transit peptide

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016644

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000223742

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P33893

KEGG Orthology (KO)

More...
KOi
K02434

Identification of Orthologs from Complete Genome Data

More...
OMAi
SDGNMQE

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.410, 1 hit
1.10.150.380, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00121 GatB, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004413 Apn/Gln-ADT_bsu
IPR017959 Asn/Gln-tRNA_amidoTrfase_suB/E
IPR006075 Asn/Gln-tRNA_Trfase_suB/E_cat
IPR018027 Asn/Gln_amidotransferase
IPR003789 Asn/Gln_tRNA_amidoTrase-B-like
IPR042114 GatB_C_1
IPR023168 GatB_Yqey_C_2
IPR017958 Gln-tRNA_amidoTrfase_suB_CS
IPR014746 Gln_synth/guanido_kin_cat_dom

The PANTHER Classification System

More...
PANTHERi
PTHR11659 PTHR11659, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02934 GatB_N, 1 hit
PF02637 GatB_Yqey, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00845 GatB_Yqey, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55931 SSF55931, 1 hit
SSF89095 SSF89095, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00133 gatB, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01234 GATB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P33893-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRLARFYSL ARTKAIHSHG APFRPEYALK CGLEIHTQLN TKNKLFSQST
60 70 80 90 100
NSATSLVDAP NHHTSYYDIA LPGTQPVLNL EAILFAMKLS LALGSQVNSI
110 120 130 140 150
SQFDRKHYFY GDQPQGYQLT QHYRPFARGG KINLSKELDD IDESAKEIGI
160 170 180 190 200
LQLQIEQDTG KSHYTETDKD VITLVDLNRS NVPLIELVTK PDFSDIKQVR
210 220 230 240 250
AFIKKYQNLV RHLHISSGDL ETGAMRVDVN LSINEYARVE LKNLPNTSSI
260 270 280 290 300
INAIKYEYQR QVELISVGDT SSLMEPETRG WTGSSTVKLR SKETTIDYRY
310 320 330 340 350
MPDPELPYIN LAPDVISGVR GLMPQLPDDI MRILMKKPYQ LSLKDAKILT
360 370 380 390 400
YNSNQNDMYN HEALRSYYLD TFREFSKLAG ERSNAKLPTN WIIHEFLGDL
410 420 430 440 450
NKLQIPLAKA KEILPPPVFA QFLKLLHEEV ISATSGKMLL FHILENFEQS
460 470 480 490 500
NCQDLSIPDF SKLIEKFELH AINQVDPQEL MDLCNDVIAQ HTDDTFIRNL
510 520 530 540
VTGKKKSSLK FLIGQGMRRS QGRIKANEFE KKFKEILNIQ W
Length:541
Mass (Da):61,869
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF426E82F1532B07D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti415P → A in CAA56028 (PubMed:7502586).Curated1
Sequence conflicti415P → A in CAA84901 (PubMed:7813418).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L22072 Genomic DNA Translation: AAC37508.1
X79489 Genomic DNA Translation: CAA56028.1
Z35841 Genomic DNA Translation: CAA84901.1
BK006936 Genomic DNA Translation: DAA07043.2

Protein sequence database of the Protein Information Resource

More...
PIRi
S45428

NCBI Reference Sequences

More...
RefSeqi
NP_009473.2, NM_001178320.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YBL080C_mRNA; YBL080C_mRNA; YBL080C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
852198

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YBL080C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22072 Genomic DNA Translation: AAC37508.1
X79489 Genomic DNA Translation: CAA56028.1
Z35841 Genomic DNA Translation: CAA84901.1
BK006936 Genomic DNA Translation: DAA07043.2
PIRiS45428
RefSeqiNP_009473.2, NM_001178320.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4N0HX-ray1.95B16-329[»]
4N0IX-ray2.00B16-329[»]
SMRiP33893
ModBaseiSearch...

Protein-protein interaction databases

BioGridi32623, 58 interactors
ComplexPortaliCPX-416 Glutamyl-tRNA(Gln) amidotransferase complex
DIPiDIP-5011N
IntActiP33893, 4 interactors
STRINGi4932.YBL080C

Proteomic databases

MaxQBiP33893
PaxDbiP33893
PRIDEiP33893

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYBL080C_mRNA; YBL080C_mRNA; YBL080C
GeneIDi852198
KEGGisce:YBL080C

Organism-specific databases

EuPathDBiFungiDB:YBL080C
SGDiS000000176 PET112

Phylogenomic databases

GeneTreeiENSGT00390000016644
HOGENOMiHOG000223742
InParanoidiP33893
KOiK02434
OMAiSDGNMQE

Enzyme and pathway databases

BioCyciYEAST:G3O-28971-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P33893

Family and domain databases

Gene3Di1.10.10.410, 1 hit
1.10.150.380, 1 hit
HAMAPiMF_00121 GatB, 1 hit
InterProiView protein in InterPro
IPR004413 Apn/Gln-ADT_bsu
IPR017959 Asn/Gln-tRNA_amidoTrfase_suB/E
IPR006075 Asn/Gln-tRNA_Trfase_suB/E_cat
IPR018027 Asn/Gln_amidotransferase
IPR003789 Asn/Gln_tRNA_amidoTrase-B-like
IPR042114 GatB_C_1
IPR023168 GatB_Yqey_C_2
IPR017958 Gln-tRNA_amidoTrfase_suB_CS
IPR014746 Gln_synth/guanido_kin_cat_dom
PANTHERiPTHR11659 PTHR11659, 1 hit
PfamiView protein in Pfam
PF02934 GatB_N, 1 hit
PF02637 GatB_Yqey, 1 hit
SMARTiView protein in SMART
SM00845 GatB_Yqey, 1 hit
SUPFAMiSSF55931 SSF55931, 1 hit
SSF89095 SSF89095, 1 hit
TIGRFAMsiTIGR00133 gatB, 1 hit
PROSITEiView protein in PROSITE
PS01234 GATB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGATB_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P33893
Secondary accession number(s): D6VPS3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: July 27, 2011
Last modified: May 8, 2019
This is version 155 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names
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