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Entry version 150 (07 Oct 2020)
Sequence version 1 (01 Feb 1994)
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Protein

Fe(2+) transporter FeoB

Gene

feoB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transporter of a GTP-driven Fe2+ uptake system, probably couples GTP-binding to channel opening and Fe2+ uptake (PubMed:12446835, PubMed:19629046). A guanine nucleotide-binding protein (G proteins) in which the guanine nucleotide binding site alternates between an active, GTP-bound state and an inactive, GDP-bound state. This protein has fast intrinsic GDP release, mediated by the G5 loop (about residues 149-158). Presumably GTP hydrolysis leads to conformational changes and channel closing (PubMed:19629046). A GDP release mechanism involving a conformational change of the G5 loop (and thus the removal of the nucleotide-binding and stabilizing interactions) would significantly reduce the affinity for GDP, and conceivably be sufficient for catalysing nucleotide release (PubMed:25374115).6 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi10 – 17GTP 1PROSITE-ProRule annotation1 Publication8
Nucleotide bindingi35 – 39GTP 2PROSITE-ProRule annotation5
Nucleotide bindingi56 – 59GTP 3PROSITE-ProRule annotation4
Nucleotide bindingi120 – 123GTPPROSITE-ProRule annotation1 Publication1 Publication4
Nucleotide bindingi149 – 151GTPPROSITE-ProRule annotationCurated2 Publications3

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Iron transport, Transport
LigandGTP-binding, Iron, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:FEOB-MONOMER
MetaCyc:FEOB-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
9.A.8.1.1, the ferrous iron uptake (feob) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Fe(2+) transporter FeoBCurated
Alternative name(s):
Ferrous iron transport protein B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:feoB
Ordered Locus Names:b3409, JW3372
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 281Cytoplasmic1 PublicationAdd BLAST281
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei282 – 302HelicalSequence analysisAdd BLAST21
Topological domaini303 – 308PeriplasmicCurated6
Transmembranei309 – 329HelicalSequence analysisAdd BLAST21
Topological domaini330 – 343CytoplasmicCuratedAdd BLAST14
Transmembranei344 – 366HelicalSequence analysisAdd BLAST23
Topological domaini367 – 382PeriplasmicCuratedAdd BLAST16
Transmembranei383 – 403HelicalSequence analysisAdd BLAST21
Topological domaini404 – 426CytoplasmicCuratedAdd BLAST23
Transmembranei427 – 447HelicalSequence analysisAdd BLAST21
Topological domaini448 – 452PeriplasmicCurated5
Transmembranei453 – 473HelicalSequence analysisAdd BLAST21
Topological domaini474 – 517CytoplasmicCuratedAdd BLAST44
Transmembranei518 – 538HelicalSequence analysisAdd BLAST21
Topological domaini539 – 663PeriplasmicCuratedAdd BLAST125
Transmembranei664 – 684HelicalSequence analysisAdd BLAST21
Topological domaini685 – 690CytoplasmicCurated6
Transmembranei691 – 711HelicalSequence analysisAdd BLAST21
Topological domaini712 – 721PeriplasmicCurated10
Transmembranei722 – 742HelicalSequence analysisAdd BLAST21
Topological domaini743 – 773Cytoplasmic1 PublicationAdd BLAST31

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Poor uptake of Fe2+.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi94D → N: No effect. 1 Publication1
Mutagenesisi123D → N: Loss of guanine nucleotide-binding specificity and Fe(2+) uptake. 1 Publication1
Mutagenesisi150 – 158STRGRGIEA → ATDTKNVQFV: 10-fold reduced affinity for GDP, corresponds to the G5 loop of human GNAI1, a slow GDP-releasing protein, in construct of residues 1-270. 1 Publication9
Mutagenesisi150S → A: Dramatically reduced GDP release-rate, 5-fold increase in affinity for GDP, in construct of residues 1-270. GTP hydrolysis rate 1.5-fold higher than wild-type. 2 Publications1
Mutagenesisi151T → A: GTP hydrolysis rate 4-fold slower than wild-type, releases GDP very quickly. 1 Publication1
Mutagenesisi152R → A: GTP hydrolysis rate 1.3-fold slower than wild-type. 1 Publication1
Mutagenesisi153G → A: GTP hydrolysis rate 1.8-fold slower than wild-type. 1 Publication1
Mutagenesisi154R → A: Dramatically reduced GDP release-rate, in construct of residues 1-270. GTP hydrolysis rate 2.7-fold slower than wild-type. 2 Publications1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002108211 – 773Fe(2+) transporter FeoBAdd BLAST773

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P33650

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P33650

PRoteomics IDEntifications database

More...
PRIDEi
P33650

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Iron uptake is repressed by the global regulator Fur in presence of Fe2+ (PubMed:12446835). Induced by hydroxyurea (PubMed:20005847).2 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

The isolated N-terminal domain (residues 1-274) forms trimers (PubMed:19629046, Ref. 10,PubMed:25374115).

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

P33650
With#Exp.IntAct
itself5EBI-7131497,EBI-7131497

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
4261727, 49 interactors
852228, 1 interactor

Database of interacting proteins

More...
DIPi
DIP-9591N

Molecular INTeraction database

More...
MINTi
P33650

STRING: functional protein association networks

More...
STRINGi
511145.b3409

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1773
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P33650

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P33650

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 169FeoB-type GPROSITE-ProRule annotationAdd BLAST167

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 274NFeoB, GTPase protein domain, binds GTP but not ATP5 PublicationsAdd BLAST274

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Contains a guanine-nucleotide-specific nucleotide-binding site (about residues 1-276) that shows slow GTP hydrolysis (PubMed:12446835, PubMed:23104801). When a non-hydrolyzable GTP analog binds to the trimeric N-terminal domain, it induces a structural shift which opens a pore (PubMed:19629046).3 Publications

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0370, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_013350_3_0_6

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P33650

KEGG Orthology (KO)

More...
KOi
K04759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P33650

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01879, FeoB, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003373, Fe2_transport_prot-B
IPR011640, Fe2_transport_prot_B_C
IPR041069, FeoB_Cyto
IPR030389, G_FEOB_dom
IPR011642, Gate_dom
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07664, FeoB_C, 1 hit
PF17910, FeoB_Cyto, 1 hit
PF02421, FeoB_N, 1 hit
PF07670, Gate, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00437, feoB, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51711, G_FEOB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P33650-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKLTIGLIG NPNSGKTTLF NQLTGSRQRV GNWAGVTVER KEGQFSTTDH
60 70 80 90 100
QVTLVDLPGT YSLTTISSQT SLDEQIACHY ILSGDADLLI NVVDASNLER
110 120 130 140 150
NLYLTLQLLE LGIPCIVALN MLDIAEKQNI RIEIDALSAR LGCPVIPLVS
160 170 180 190 200
TRGRGIEALK LAIDRYKANE NVELVHYAQP LLNEADSLAK VMPSDIPLKQ
210 220 230 240 250
RRWLGLQMLE GDIYSRAYAG EASQHLDAAL ARLRNEMDDP ALHIADARYQ
260 270 280 290 300
CIAAICDVVS NTLTAEPSRF TTAVDKIVLN RFLGLPIFLF VMYLMFLLAI
310 320 330 340 350
NIGGALQPLF DVGSVALFVH GIQWIGYTLH FPDWLTIFLA QGLGGGINTV
360 370 380 390 400
LPLVPQIGMM YLFLSFLEDS GYMARAAFVM DRLMQALGLP GKSFVPLIVG
410 420 430 440 450
FGCNVPSVMG ARTLDAPRER LMTIMMAPFM SCGARLAIFA VFAAAFFGQN
460 470 480 490 500
GALAVFSLYM LGIVMAVLTG LMLKYTIMRG EATPFVMELP VYHVPHVKSL
510 520 530 540 550
IIQTWQRLKG FVLRAGKVII IVSIFLSAFN SFSLSGKIVD NINDSALASV
560 570 580 590 600
SRVITPVFKP IGVHEDNWQA TVGLFTGAMA KEVVVGTLNT LYTAENIQDE
610 620 630 640 650
EFNPAEFNLG EELFSAIDET WQSLKDTFSL SVLMNPIEAS KGDGEMGTGA
660 670 680 690 700
MGVMDQKFGS AAAAYSYLIF VLLYVPCISV MGAIARESSR GWMGFSILWG
710 720 730 740 750
LNIAYSLATL FYQVASYSQH PTYSLVCILA VILFNIVVIG LLRRARSRVD
760 770
IELLATRKSV SSCCAASTTG DCH
Length:773
Mass (Da):84,474
Last modified:February 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1150A14B131AB9AE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X71063 Genomic DNA Translation: CAA50387.1
U18997 Genomic DNA Translation: AAA58207.1
U00096 Genomic DNA Translation: AAC76434.1
AP009048 Genomic DNA Translation: BAE77882.1
AY625107 Genomic DNA Translation: AAT42461.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A36932

NCBI Reference Sequences

More...
RefSeqi
NP_417868.1, NC_000913.3
WP_000737039.1, NZ_SSZK01000008.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC76434; AAC76434; b3409
BAE77882; BAE77882; BAE77882

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
947919

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW3372
eco:b3409

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1411691.4.peg.3320

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X71063 Genomic DNA Translation: CAA50387.1
U18997 Genomic DNA Translation: AAA58207.1
U00096 Genomic DNA Translation: AAC76434.1
AP009048 Genomic DNA Translation: BAE77882.1
AY625107 Genomic DNA Translation: AAT42461.1
PIRiA36932
RefSeqiNP_417868.1, NC_000913.3
WP_000737039.1, NZ_SSZK01000008.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3HYRX-ray2.20A/B/C1-270[»]
3HYTX-ray2.74A/B/C1-270[»]
3I8SX-ray1.80A/B/C1-274[»]
3I8XX-ray2.25A/B/C1-274[»]
3I92X-ray3.00A/B/C1-274[»]
4Q00X-ray2.10A/B/C1-261[»]
4Q5IX-ray2.80A/B/C/D/E/F1-270[»]
4R98X-ray2.22A/B1-270[»]
SMRiP33650
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi4261727, 49 interactors
852228, 1 interactor
DIPiDIP-9591N
MINTiP33650
STRINGi511145.b3409

Protein family/group databases

TCDBi9.A.8.1.1, the ferrous iron uptake (feob) family

Proteomic databases

jPOSTiP33650
PaxDbiP33650
PRIDEiP33650

Genome annotation databases

EnsemblBacteriaiAAC76434; AAC76434; b3409
BAE77882; BAE77882; BAE77882
GeneIDi947919
KEGGiecj:JW3372
eco:b3409
PATRICifig|1411691.4.peg.3320

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB2026

Phylogenomic databases

eggNOGiCOG0370, Bacteria
HOGENOMiCLU_013350_3_0_6
InParanoidiP33650
KOiK04759
PhylomeDBiP33650

Enzyme and pathway databases

BioCyciEcoCyc:FEOB-MONOMER
MetaCyc:FEOB-MONOMER

Miscellaneous databases

EvolutionaryTraceiP33650

Protein Ontology

More...
PROi
PR:P33650

Family and domain databases

CDDicd01879, FeoB, 1 hit
InterProiView protein in InterPro
IPR003373, Fe2_transport_prot-B
IPR011640, Fe2_transport_prot_B_C
IPR041069, FeoB_Cyto
IPR030389, G_FEOB_dom
IPR011642, Gate_dom
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF07664, FeoB_C, 1 hit
PF17910, FeoB_Cyto, 1 hit
PF02421, FeoB_N, 1 hit
PF07670, Gate, 2 hits
SUPFAMiSSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR00437, feoB, 1 hit
PROSITEiView protein in PROSITE
PS51711, G_FEOB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFEOB_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P33650
Secondary accession number(s): Q2M774, Q6IU42
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: October 7, 2020
This is version 150 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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