UniProtKB - P33363 (BGLX_ECOLI)
Protein
Periplasmic beta-glucosidase
Gene
bglX
Organism
Escherichia coli (strain K12)
Status
Functioni
Catalytic activityi
- Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose. EC:3.2.1.21
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 287 | By similarity | 1 |
GO - Molecular functioni
- beta-glucosidase activity Source: EcoliWiki
- glucosidase activity Source: EcoliWiki
- scopolin beta-glucosidase activity Source: UniProtKB-EC
GO - Biological processi
- glucan catabolic process Source: GO_Central
Keywordsi
Molecular function | Glycosidase, Hydrolase |
Enzyme and pathway databases
BioCyci | EcoCyc:EG12013-MONOMER MetaCyc:EG12013-MONOMER |
Protein family/group databases
CAZyi | GH3, Glycoside Hydrolase Family 3 |
Names & Taxonomyi
Protein namesi | Recommended name: Periplasmic beta-glucosidase (EC:3.2.1.21)Alternative name(s): Beta-D-glucoside glucohydrolase Cellobiase Gentiobiase |
Gene namesi | Name:bglX Synonyms:yohA Ordered Locus Names:b2132, JW2120 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Other locations
Other locations
- outer membrane-bounded periplasmic space Source: EcoCyc
- periplasmic space Source: EcoliWiki
Keywords - Cellular componenti
PeriplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 20 | Sequence analysisAdd BLAST | 20 | |
ChainiPRO_0000011781 | 21 – 765 | Periplasmic beta-glucosidaseAdd BLAST | 745 |
Proteomic databases
jPOSTi | P33363 |
PaxDbi | P33363 |
PRIDEi | P33363 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260451, 32 interactors |
DIPi | DIP-9218N |
IntActi | P33363, 16 interactors |
STRINGi | 511145.b2132 |
Family & Domainsi
Sequence similaritiesi
Belongs to the glycosyl hydrolase 3 family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | COG1472, Bacteria |
HOGENOMi | CLU_004542_5_1_6 |
InParanoidi | P33363 |
PhylomeDBi | P33363 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.20.20.300, 1 hit 3.40.50.1700, 1 hit |
InterProi | View protein in InterPro IPR026891, Fn3-like IPR019800, Glyco_hydro_3_AS IPR002772, Glyco_hydro_3_C IPR036881, Glyco_hydro_3_C_sf IPR001764, Glyco_hydro_3_N IPR036962, Glyco_hydro_3_N_sf IPR017853, Glycoside_hydrolase_SF IPR013783, Ig-like_fold |
Pfami | View protein in Pfam PF14310, Fn3-like, 1 hit PF00933, Glyco_hydro_3, 1 hit PF01915, Glyco_hydro_3_C, 1 hit |
PRINTSi | PR00133, GLHYDRLASE3 |
SMARTi | View protein in SMART SM01217, Fn3_like, 1 hit |
SUPFAMi | SSF51445, SSF51445, 1 hit SSF52279, SSF52279, 1 hit |
PROSITEi | View protein in PROSITE PS00775, GLYCOSYL_HYDROL_F3, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P33363-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKWLCSVGIA VSLALQPALA DDLFGNHPLT PEARDAFVTE LLKKMTVDEK
60 70 80 90 100
IGQLRLISVG PDNPKEAIRE MIKDGQVGAI FNTVTRQDIR AMQDQVMELS
110 120 130 140 150
RLKIPLFFAY DVLHGQRTVF PISLGLASSF NLDAVKTVGR VSAYEAADDG
160 170 180 190 200
LNMTWAPMVD VSRDPRWGRA SEGFGEDTYL TSTMGKTMVE AMQGKSPADR
210 220 230 240 250
YSVMTSVKHF AAYGAVEGGK EYNTVDMSPQ RLFNDYMPPY KAGLDAGSGA
260 270 280 290 300
VMVALNSLNG TPATSDSWLL KDVLRDQWGF KGITVSDHGA IKELIKHGTA
310 320 330 340 350
ADPEDAVRVA LKSGINMSMS DEYYSKYLPG LIKSGKVTMA ELDDAARHVL
360 370 380 390 400
NVKYDMGLFN DPYSHLGPKE SDPVDTNAES RLHRKEAREV ARESLVLLKN
410 420 430 440 450
RLETLPLKKS ATIAVVGPLA DSKRDVMGSW SAAGVADQSV TVLTGIKNAV
460 470 480 490 500
GENGKVLYAK GANVTSDKGI IDFLNQYEEA VKVDPRSPQE MIDEAVQTAK
510 520 530 540 550
QSDVVVAVVG EAQGMAHEAS SRTDITIPQS QRDLIAALKA TGKPLVLVLM
560 570 580 590 600
NGRPLALVKE DQQADAILET WFAGTEGGNA IADVLFGDYN PSGKLPMSFP
610 620 630 640 650
RSVGQIPVYY SHLNTGRPYN ADKPNKYTSR YFDEANGALY PFGYGLSYTT
660 670 680 690 700
FTVSDVKLSA PTMKRDGKVT ASVQVTNTGK REGATVVQMY LQDVTASMSR
710 720 730 740 750
PVKQLKGFEK ITLKPGETQT VSFPIDIEAL KFWNQQMKYD AEPGKFNVFI
760
GTDSARVKKG EFELL
Sequence cautioni
The sequence AAA60495 differs from that shown. Reason: Erroneous initiation.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U15049 Genomic DNA Translation: AAB38487.1 U00007 Genomic DNA Translation: AAA60495.1 Different initiation. U00096 Genomic DNA Translation: AAC75193.1 AP009048 Genomic DNA Translation: BAE76609.1 |
PIRi | C64981 |
RefSeqi | NP_416636.1, NC_000913.3 WP_000871504.1, NZ_SSZK01000011.1 |
Genome annotation databases
EnsemblBacteriai | AAC75193; AAC75193; b2132 BAE76609; BAE76609; BAE76609 |
GeneIDi | 946682 |
KEGGi | ecj:JW2120 eco:b2132 |
PATRICi | fig|511145.12.peg.2212 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U15049 Genomic DNA Translation: AAB38487.1 U00007 Genomic DNA Translation: AAA60495.1 Different initiation. U00096 Genomic DNA Translation: AAC75193.1 AP009048 Genomic DNA Translation: BAE76609.1 |
PIRi | C64981 |
RefSeqi | NP_416636.1, NC_000913.3 WP_000871504.1, NZ_SSZK01000011.1 |
3D structure databases
SMRi | P33363 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260451, 32 interactors |
DIPi | DIP-9218N |
IntActi | P33363, 16 interactors |
STRINGi | 511145.b2132 |
Protein family/group databases
CAZyi | GH3, Glycoside Hydrolase Family 3 |
Proteomic databases
jPOSTi | P33363 |
PaxDbi | P33363 |
PRIDEi | P33363 |
Genome annotation databases
EnsemblBacteriai | AAC75193; AAC75193; b2132 BAE76609; BAE76609; BAE76609 |
GeneIDi | 946682 |
KEGGi | ecj:JW2120 eco:b2132 |
PATRICi | fig|511145.12.peg.2212 |
Organism-specific databases
EchoBASEi | EB1951 |
Phylogenomic databases
eggNOGi | COG1472, Bacteria |
HOGENOMi | CLU_004542_5_1_6 |
InParanoidi | P33363 |
PhylomeDBi | P33363 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG12013-MONOMER MetaCyc:EG12013-MONOMER |
Miscellaneous databases
PROi | PR:P33363 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.20.20.300, 1 hit 3.40.50.1700, 1 hit |
InterProi | View protein in InterPro IPR026891, Fn3-like IPR019800, Glyco_hydro_3_AS IPR002772, Glyco_hydro_3_C IPR036881, Glyco_hydro_3_C_sf IPR001764, Glyco_hydro_3_N IPR036962, Glyco_hydro_3_N_sf IPR017853, Glycoside_hydrolase_SF IPR013783, Ig-like_fold |
Pfami | View protein in Pfam PF14310, Fn3-like, 1 hit PF00933, Glyco_hydro_3, 1 hit PF01915, Glyco_hydro_3_C, 1 hit |
PRINTSi | PR00133, GLHYDRLASE3 |
SMARTi | View protein in SMART SM01217, Fn3_like, 1 hit |
SUPFAMi | SSF51445, SSF51445, 1 hit SSF52279, SSF52279, 1 hit |
PROSITEi | View protein in PROSITE PS00775, GLYCOSYL_HYDROL_F3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | BGLX_ECOLI | |
Accessioni | P33363Primary (citable) accession number: P33363 Secondary accession number(s): Q2MAU7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1994 |
Last sequence update: | February 1, 1995 | |
Last modified: | December 2, 2020 | |
This is version 151 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries - SIMILARITY comments
Index of protein domains and families