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Entry version 119 (07 Oct 2020)
Sequence version 2 (01 Nov 1997)
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Protein

Uncharacterized protein YehI

Gene

yehI

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:EG11995-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein YehI
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yehI
Ordered Locus Names:b2118, JW2105
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001691311 – 1210Uncharacterized protein YehIAdd BLAST1210

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P33346

PRoteomics IDEntifications database

More...
PRIDEi
P33346

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
4259176, 37 interactors
850993, 2 interactors

Protein interaction database and analysis system

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IntActi
P33346, 8 interactors

STRING: functional protein association networks

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STRINGi
511145.b2118

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

To E.coli molybdate metabolism regulator (MolR).Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
COG3831, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006807_1_0_6

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR025406, DUF4132

Pfam protein domain database

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Pfami
View protein in Pfam
PF13569, DUF4132, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P33346-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDKELPWLAD NAQLELKYKK GKTPLSHRRW PGEPVSVITG SLIQTLGDEL
60 70 80 90 100
LQKAEKKKNI VWRYENFSLE WQSAITQAIN LIGEHKPSIP ARTMAALACI
110 120 130 140 150
AQNDSQQLLD EIVQQEGLEY ATEVVIARQF IARCYESDPL VVTLQYQDED
160 170 180 190 200
YGYGYRSETY NEFDLRLRKH LSLAEESCWQ RCADKLIAAL PGINKVRRPF
210 220 230 240 250
IALILPEKPE IANELVGLEC PRTHFHSKEW LKVVANDPTA VRKLEHYWSQ
260 270 280 290 300
DIFSDREASY MSHENHFGYA ACAALLREQG LAAIPRLAMY AHKEDCGSLL
310 320 330 340 350
VQINHPQVIR TLLLVADKNK PSLQRVAKYH KNFPHATLAA LAELLALTEP
360 370 380 390 400
PARPGYPIIE DKKLPAQQKA RDEYWRTLLQ TLMASQPQLA AEVMPWLSTQ
410 420 430 440 450
PQSVLKSYLS APPKPVIDGT DNSNLPEILV SPPWRSKKKM TAPRLDLAPL
460 470 480 490 500
ELTPQVYWQP GEQERLAATE PARYFSTESL AQRMEQKSGR VVLQELGFGD
510 520 530 540 550
DVWLFLNYIL PGKLDAARNS LFVQWHYYQG RVEEILNGWN SPEAQLAEQA
560 570 580 590 600
LRSGHIEALI NIWENDNYSH YRPEKSVWNL YLLAQLPREM ALTFWLRINE
610 620 630 640 650
KKHLFAGEDY FLSILGLDAL PGLLLAFSHR PKETFPLILN FGATELALPV
660 670 680 690 700
AHVWRRFAAQ RDLARQWILQ WPEHTASALI PLVFTKPSDN SEAALLALRL
710 720 730 740 750
LYEQGHGELL QTVANRWQRT DVWSALEQLL KQGPMDIYPA RIPKAPDFWH
760 770 780 790 800
PQMWSRPRLI TNNQTVTNDA LEIIGEMLRF TQGGRFYSGL EQLKTFCQPQ
810 820 830 840 850
TLAAFAWDLF TAWQQAGAPA KDNWAFLALS LFGDESTARD LTTQILAWPQ
860 870 880 890 900
EGKSARAVSG LNILTLMNND MALIQLHHIS QRAKSRPLRD NAAEFLQVVA
910 920 930 940 950
ENRGLSQEEL ADRLVPTLGL DDPQALSFDF GPRQFTVRFD ENLNPVIFDQ
960 970 980 990 1000
QNVRQKSVPR LRADDDQLKA PEALARLKGL KKDATQVSKN LLPRLETALR
1010 1020 1030 1040 1050
TTRRWSLADF HSLFVNHPFT RLVTQRLIWG VYPANEPRCL LKAFRVAAEG
1060 1070 1080 1090 1100
EFCNAQDEPI DLPADALIGI AHPLEMTAEM RSEFAQLFAD YEIMPPFRQL
1110 1120 1130 1140 1150
SRRTVLLTPD ESTSNSLTRW EGKSATVGQL MGMRYKGWES GYEDAFVYNL
1160 1170 1180 1190 1200
GEYRLVLKFS PGFNHYNVDS KALMSFRSLR VYRDNKSVTF AELDVFDLSE
1210
ALSAPDVIFH
Length:1,210
Mass (Da):138,068
Last modified:November 1, 1997 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0C2D3412D3CD6574
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAA60478 differs from that shown. Reason: Frameshift.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
U00007 Genomic DNA Translation: AAA60478.1 Frameshift.
U00096 Genomic DNA Translation: AAC75179.1
AP009048 Genomic DNA Translation: BAE76593.1

Protein sequence database of the Protein Information Resource

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PIRi
E64979

NCBI Reference Sequences

More...
RefSeqi
NP_416621.1, NC_000913.3
WP_000356817.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC75179; AAC75179; b2118
BAE76593; BAE76593; BAE76593

Database of genes from NCBI RefSeq genomes

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GeneIDi
946649

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW2105
eco:b2118

Pathosystems Resource Integration Center (PATRIC)

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PATRICi
fig|511145.12.peg.2195

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00007 Genomic DNA Translation: AAA60478.1 Frameshift.
U00096 Genomic DNA Translation: AAC75179.1
AP009048 Genomic DNA Translation: BAE76593.1
PIRiE64979
RefSeqiNP_416621.1, NC_000913.3
WP_000356817.1, NZ_LN832404.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi4259176, 37 interactors
850993, 2 interactors
IntActiP33346, 8 interactors
STRINGi511145.b2118

Proteomic databases

PaxDbiP33346
PRIDEiP33346

Genome annotation databases

EnsemblBacteriaiAAC75179; AAC75179; b2118
BAE76593; BAE76593; BAE76593
GeneIDi946649
KEGGiecj:JW2105
eco:b2118
PATRICifig|511145.12.peg.2195

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB1936

Phylogenomic databases

eggNOGiCOG3831, Bacteria
HOGENOMiCLU_006807_1_0_6

Enzyme and pathway databases

BioCyciEcoCyc:EG11995-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P33346

Family and domain databases

InterProiView protein in InterPro
IPR025406, DUF4132
PfamiView protein in Pfam
PF13569, DUF4132, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYEHI_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P33346
Secondary accession number(s): P76430, Q2MAW3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: November 1, 1997
Last modified: October 7, 2020
This is version 119 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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