UniProtKB - P33342 (YEHC_ECOLI)
Protein
Probable fimbrial chaperone YehC
Gene
yehC
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of the yehABCD fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches.1 Publication
Miscellaneous
The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.1 Publication
GO - Biological processi
- cell wall organization Source: InterPro
- chaperone-mediated protein folding Source: InterPro
- pilus organization Source: InterPro
Keywordsi
Molecular function | Chaperone |
Biological process | Fimbrium biogenesis |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11989-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Probable fimbrial chaperone YehC |
Gene namesi | Name:yehC Ordered Locus Names:b2110, JW2097 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Other locations
- Periplasm By similarity
Other locations
- outer membrane-bounded periplasmic space Source: InterPro
Keywords - Cellular componenti
PeriplasmPathology & Biotechi
Disruption phenotypei
Deletion of the operon under classical laboratory conditions does not result in any major effect on E.coli capacity to form biofilms compared with the wild-type strain.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 31 | Sequence analysisAdd BLAST | 31 | |
ChainiPRO_0000009293 | 32 – 239 | Probable fimbrial chaperone YehCAdd BLAST | 208 |
Proteomic databases
PaxDbi | P33342 |
PRIDEi | P33342 |
Expressioni
Inductioni
Expression is negatively regulated by H-NS and subjected to cAMP receptor protein (CRP)-mediated catabolite repression.1 Publication
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260436, 28 interactors |
IntActi | P33342, 4 interactors |
STRINGi | 511145.b2110 |
Family & Domainsi
Sequence similaritiesi
Belongs to the periplasmic pilus chaperone family.Curated
Keywords - Domaini
Immunoglobulin domain, SignalPhylogenomic databases
eggNOGi | COG3121, Bacteria |
HOGENOMi | CLU_070768_0_1_6 |
PhylomeDBi | P33342 |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR013783, Ig-like_fold IPR008962, PapD-like_sf IPR036316, Pili_assmbl_chap_C_dom_sf IPR001829, Pili_assmbl_chaperone_bac IPR016148, Pili_assmbl_chaperone_C IPR018046, Pili_assmbl_chaperone_CS IPR016147, Pili_assmbl_chaperone_N |
Pfami | View protein in Pfam PF02753, PapD_C, 1 hit PF00345, PapD_N, 1 hit |
PRINTSi | PR00969, CHAPERONPILI |
SUPFAMi | SSF49354, SSF49354, 1 hit SSF49584, SSF49584, 1 hit |
PROSITEi | View protein in PROSITE PS00635, PILI_CHAPERONE, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P33342-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAIPWRPFN LRGIKMKGLL SLLIFSMVLP AHAGIVIYGT RIIYPAENKE
60 70 80 90 100
VMVQLMNQGN RSSLLQAWID DGDTSLPPEK IQVPFMLTPP VAKIGANSGQ
110 120 130 140 150
QVKIKIMPNK LPTNKESIFY LNVLDIPPNS PEQEGKNALK FAMQNRIKLF
160 170 180 190 200
YRPAGIAPVN KATFKKLLVN RSGNGLVIKN DSANWVTISD VKANNVKVNY
210 220 230
ETIMIAPLES QSVNVKSNNA NNWHLTIIDD HGNYISDKI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00007 Genomic DNA Translation: AAA60474.1 U00096 Genomic DNA Translation: AAC75171.1 AP009048 Genomic DNA Translation: BAE76588.1 |
PIRi | E64978 |
RefSeqi | NP_416613.1, NC_000913.3 |
Genome annotation databases
EnsemblBacteriai | AAC75171; AAC75171; b2110 BAE76588; BAE76588; BAE76588 |
GeneIDi | 946621 |
KEGGi | ecj:JW2097 eco:b2110 |
PATRICi | fig|511145.12.peg.2187 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00007 Genomic DNA Translation: AAA60474.1 U00096 Genomic DNA Translation: AAC75171.1 AP009048 Genomic DNA Translation: BAE76588.1 |
PIRi | E64978 |
RefSeqi | NP_416613.1, NC_000913.3 |
3D structure databases
SMRi | P33342 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260436, 28 interactors |
IntActi | P33342, 4 interactors |
STRINGi | 511145.b2110 |
Proteomic databases
PaxDbi | P33342 |
PRIDEi | P33342 |
Genome annotation databases
EnsemblBacteriai | AAC75171; AAC75171; b2110 BAE76588; BAE76588; BAE76588 |
GeneIDi | 946621 |
KEGGi | ecj:JW2097 eco:b2110 |
PATRICi | fig|511145.12.peg.2187 |
Organism-specific databases
EchoBASEi | EB1932 |
Phylogenomic databases
eggNOGi | COG3121, Bacteria |
HOGENOMi | CLU_070768_0_1_6 |
PhylomeDBi | P33342 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11989-MONOMER |
Miscellaneous databases
PROi | PR:P33342 |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR013783, Ig-like_fold IPR008962, PapD-like_sf IPR036316, Pili_assmbl_chap_C_dom_sf IPR001829, Pili_assmbl_chaperone_bac IPR016148, Pili_assmbl_chaperone_C IPR018046, Pili_assmbl_chaperone_CS IPR016147, Pili_assmbl_chaperone_N |
Pfami | View protein in Pfam PF02753, PapD_C, 1 hit PF00345, PapD_N, 1 hit |
PRINTSi | PR00969, CHAPERONPILI |
SUPFAMi | SSF49354, SSF49354, 1 hit SSF49584, SSF49584, 1 hit |
PROSITEi | View protein in PROSITE PS00635, PILI_CHAPERONE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YEHC_ECOLI | |
Accessioni | P33342Primary (citable) accession number: P33342 Secondary accession number(s): Q2MAW8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1994 |
Last sequence update: | February 1, 1994 | |
Last modified: | April 7, 2021 | |
This is version 140 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families