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UniProtKB - P33207 (FABG_ARATH)
Protein
3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic
Gene
At1g24360
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Catalytic activityi
- EC:1.1.1.100
: fatty acid biosynthesis Pathwayi
This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 213 | SubstrateBy similarity | 1 | |
Active sitei | 226 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 81 – 105 | NADPBy similarityAdd BLAST | 25 |
GO - Molecular functioni
- 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity Source: TAIR
- copper ion binding Source: TAIR
- NAD binding Source: InterPro
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: GO_Central
GO - Biological processi
- fatty acid elongation Source: GO_Central
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism |
Ligand | NADP |
Enzyme and pathway databases
BioCyci | ARA:AT1G24360-MONOMER |
UniPathwayi | UPA00094 |
Names & Taxonomyi
Protein namesi | Recommended name: 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic (EC:1.1.1.100)Alternative name(s): 3-ketoacyl-acyl carrier protein reductase |
Gene namesi | Ordered Locus Names:At1g24360 ORF Names:F21J9.2, F3I6.30 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G24360 |
TAIRi | locus:2024021, AT1G24360 |
Subcellular locationi
Chloroplast
Other locations
Note: And non-photosynthetic plastids.
Chloroplast
- chloroplast Source: TAIR
- chloroplast envelope Source: TAIR
- chloroplast stroma Source: TAIR
Nucleus
- nucleus Source: TAIR
Other locations
- plastid Source: TAIR
Keywords - Cellular componenti
Chloroplast, PlastidPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 57 | ChloroplastSequence analysisCombined sourcesAdd BLAST | 57 | |
ChainiPRO_0000031976 | 58 – 319 | 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplasticAdd BLAST | 262 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 58 | N-acetylalanineCombined sources | 1 |
Keywords - PTMi
AcetylationProteomic databases
PaxDbi | P33207 |
PRIDEi | P33207 |
ProteomicsDBi | 222314 |
PTM databases
iPTMneti | P33207 |
MetOSitei | P33207 |
Expressioni
Gene expression databases
ExpressionAtlasi | P33207, baseline and differential |
Genevisiblei | P33207, AT |
Interactioni
Subunit structurei
Homotetramer.
CuratedProtein-protein interaction databases
BioGRIDi | 24291, 16 interactors |
STRINGi | 3702.AT1G24360.1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the short-chain dehydrogenases/reductases (SDR) family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG1200, Eukaryota |
HOGENOMi | CLU_010194_1_3_1 |
InParanoidi | P33207 |
OMAi | QLLMRMS |
OrthoDBi | 1226147at2759 |
PhylomeDBi | P33207 |
Family and domain databases
InterProi | View protein in InterPro IPR011284, 3oxo_ACP_reduc IPR036291, NAD(P)-bd_dom_sf IPR020904, Sc_DH/Rdtase_CS IPR002347, SDR_fam |
PRINTSi | PR00081, GDHRDH PR00080, SDRFAMILY |
SUPFAMi | SSF51735, SSF51735, 1 hit |
TIGRFAMsi | TIGR01830, 3oxo_ACP_reduc, 1 hit |
PROSITEi | View protein in PROSITE PS00061, ADH_SHORT, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P33207-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAAVAAPRL ISLKAVAKLG FREISQIRQL APLHSAIPHF GMLRCRSRQP
60 70 80 90 100
FSTSVVKAQA TATEQSPGEV VQKVESPVVV ITGASRGIGK AIALALGKAG
110 120 130 140 150
CKVLVNYARS AKEAEEVAKQ IEEYGGQAIT FGGDVSKATD VDAMMKTALD
160 170 180 190 200
KWGTIDVVVN NAGITRDTLL IRMKQSQWDE VIALNLTGVF LCTQAAVKIM
210 220 230 240 250
MKKKRGRIIN ISSVVGLIGN IGQANYAAAK GGVISFSKTA AREGASRNIN
260 270 280 290 300
VNVVCPGFIA SDMTAELGED MEKKILGTIP LGRYGKAEEV AGLVEFLALS
310
PAASYITGQA FTIDGGIAI
Sequence cautioni
The sequence AAC00590 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAF97951 differs from that shown. Reason: Erroneous gene model prediction.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 17 | A → G in CAA45794 (PubMed:1575676).Curated | 1 | |
Sequence conflicti | 227 – 229 | AAA → TAT in CAA45794 (PubMed:1575676).Curated | 3 | |
Sequence conflicti | 238 – 240 | KTA → ETP in CAA45794 (PubMed:1575676).Curated | 3 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X64464 mRNA Translation: CAA45794.1 AC000103 Genomic DNA Translation: AAF97951.1 Sequence problems. AC002396 Genomic DNA Translation: AAC00590.1 Sequence problems. CP002684 Genomic DNA Translation: AEE30522.1 AF324985 mRNA Translation: AAG40337.1 AY059816 mRNA Translation: AAL24298.1 AY081491 mRNA Translation: AAM10053.1 |
PIRi | A86378 S22416 T00667 |
RefSeqi | NP_564216.1, NM_102282.4 |
Genome annotation databases
EnsemblPlantsi | AT1G24360.1; AT1G24360.1; AT1G24360 |
GeneIDi | 839053 |
Gramenei | AT1G24360.1; AT1G24360.1; AT1G24360 |
KEGGi | ath:AT1G24360 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X64464 mRNA Translation: CAA45794.1 AC000103 Genomic DNA Translation: AAF97951.1 Sequence problems. AC002396 Genomic DNA Translation: AAC00590.1 Sequence problems. CP002684 Genomic DNA Translation: AEE30522.1 AF324985 mRNA Translation: AAG40337.1 AY059816 mRNA Translation: AAL24298.1 AY081491 mRNA Translation: AAM10053.1 |
PIRi | A86378 S22416 T00667 |
RefSeqi | NP_564216.1, NM_102282.4 |
3D structure databases
SMRi | P33207 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 24291, 16 interactors |
STRINGi | 3702.AT1G24360.1 |
PTM databases
iPTMneti | P33207 |
MetOSitei | P33207 |
Proteomic databases
PaxDbi | P33207 |
PRIDEi | P33207 |
ProteomicsDBi | 222314 |
Genome annotation databases
EnsemblPlantsi | AT1G24360.1; AT1G24360.1; AT1G24360 |
GeneIDi | 839053 |
Gramenei | AT1G24360.1; AT1G24360.1; AT1G24360 |
KEGGi | ath:AT1G24360 |
Organism-specific databases
Araporti | AT1G24360 |
TAIRi | locus:2024021, AT1G24360 |
Phylogenomic databases
eggNOGi | KOG1200, Eukaryota |
HOGENOMi | CLU_010194_1_3_1 |
InParanoidi | P33207 |
OMAi | QLLMRMS |
OrthoDBi | 1226147at2759 |
PhylomeDBi | P33207 |
Enzyme and pathway databases
UniPathwayi | UPA00094 |
BioCyci | ARA:AT1G24360-MONOMER |
Miscellaneous databases
PROi | PR:P33207 |
Gene expression databases
ExpressionAtlasi | P33207, baseline and differential |
Genevisiblei | P33207, AT |
Family and domain databases
InterProi | View protein in InterPro IPR011284, 3oxo_ACP_reduc IPR036291, NAD(P)-bd_dom_sf IPR020904, Sc_DH/Rdtase_CS IPR002347, SDR_fam |
PRINTSi | PR00081, GDHRDH PR00080, SDRFAMILY |
SUPFAMi | SSF51735, SSF51735, 1 hit |
TIGRFAMsi | TIGR01830, 3oxo_ACP_reduc, 1 hit |
PROSITEi | View protein in PROSITE PS00061, ADH_SHORT, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | FABG_ARATH | |
Accessioni | P33207Primary (citable) accession number: P33207 Secondary accession number(s): O04463, Q9FPJ6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1994 |
Last sequence update: | January 10, 2003 | |
Last modified: | February 23, 2022 | |
This is version 170 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families