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Entry version 169 (29 Sep 2021)
Sequence version 1 (01 Feb 1994)
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Protein

Ribosome assembly factor MRT4

Gene

MRT4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.

4 Publications

Miscellaneous

Present with 18200 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processRibosome biogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ribosome assembly factor MRT41 Publication
Alternative name(s):
mRNA turnover protein 41 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MRT41 Publication
Ordered Locus Names:YKL009WImported
ORF Names:YKL160
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XI

Organism-specific databases

Saccharomyces Genome Database

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SGDi
S000001492, MRT4

Eukaryotic Pathogen, Vector and Host Database Resources

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VEuPathDBi
FungiDB:YKL009W

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi68G → D: Bypasses the requirement for phosphatase YVH1 for the release of MRT4. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001548151 – 236Ribosome assembly factor MRT4Add BLAST236

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P33201

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P33201

PRoteomics IDEntifications database

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PRIDEi
P33201

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P33201

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Associates with the pre-60S ribosomal particle.

4 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
34123, 475 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1604, Small ribosomal subunit processome, variant 1
CPX-1607, Small ribosomal subunit processome, variant 2
CPX-1608, Small ribosomal subunit processome, variant 3

Database of interacting proteins

More...
DIPi
DIP-5283N

Protein interaction database and analysis system

More...
IntActi
P33201, 30 interactors

Molecular INTeraction database

More...
MINTi
P33201

STRING: functional protein association networks

More...
STRINGi
4932.YKL009W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P33201, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P33201

Database of comparative protein structure models

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ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

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PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0816, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000168261

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_071690_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P33201

Identification of Orthologs from Complete Genome Data

More...
OMAi
LEWAENY

Family and domain databases

Conserved Domains Database

More...
CDDi
cd05796, Ribosomal_P0_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.1730, 1 hit
3.90.105.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033867, Mrt4
IPR043141, Ribosomal_L10-like_sf
IPR001790, Ribosomal_L10P
IPR043164, RL10_insert_sf
IPR040637, RL10P_insert

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00466, Ribosomal_L10, 1 hit
PF17777, RL10P_insert, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF160369, SSF160369, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P33201-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRSKRSKLV TLAQTDKKGR ENKERIFDEV REALDTYRYV WVLHLDDVRT
60 70 80 90 100
PVLQEIRTSW AGSKLIMGKR KVLQKALGEK REEEYKENLY QLSKLCSGVT
110 120 130 140 150
GLLFTDEDVN TVKEYFKSYV RSDYSRPNTK APLTFTIPEG IVYSRGGQIP
160 170 180 190 200
AEEDVPMIHS LEPTMRNKFE IPTKIKAGKI TIDSPYLVCT EGEKLDVRQA
210 220 230
LILKQFGIAA SEFKVKVSAY YDNDSSTVES TNINME
Length:236
Mass (Da):27,058
Last modified:February 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9FCFDEE9F009F427
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
S53418 Genomic DNA Translation: AAB24904.1
X61398 Genomic DNA No translation available.
Z28009 Genomic DNA Translation: CAA81844.1
S59773 Genomic DNA Translation: AAC60552.1
BK006944 Genomic DNA Translation: DAA09147.1

Protein sequence database of the Protein Information Resource

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PIRi
S30013

NCBI Reference Sequences

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RefSeqi
NP_012916.1, NM_001179575.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YKL009W_mRNA; YKL009W; YKL009W

Database of genes from NCBI RefSeq genomes

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GeneIDi
853860

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YKL009W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S53418 Genomic DNA Translation: AAB24904.1
X61398 Genomic DNA No translation available.
Z28009 Genomic DNA Translation: CAA81844.1
S59773 Genomic DNA Translation: AAC60552.1
BK006944 Genomic DNA Translation: DAA09147.1
PIRiS30013
RefSeqiNP_012916.1, NM_001179575.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3JCTelectron microscopy3.08W1-236[»]
4V7Felectron microscopy8.70n1-236[»]
5FL8electron microscopy9.50n1-236[»]
5JCSelectron microscopy9.50n1-236[»]
6ELZelectron microscopy3.30W1-236[»]
6EM1electron microscopy3.60W1-236[»]
6EM5electron microscopy4.30W1-236[»]
6FT6electron microscopy3.90W1-236[»]
6M62electron microscopy3.20W1-236[»]
6N8Jelectron microscopy3.50W1-236[»]
6N8Kelectron microscopy3.60W1-236[»]
6N8Lelectron microscopy3.60W1-236[»]
6YLGelectron microscopy3.00W1-236[»]
6YLHelectron microscopy3.10W1-236[»]
6YLXelectron microscopy3.90W1-236[»]
6YLYelectron microscopy3.80W1-236[»]
7BT6electron microscopy3.12W1-236[»]
7BTBelectron microscopy3.22W1-236[»]
SMRiP33201
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi34123, 475 interactors
ComplexPortaliCPX-1604, Small ribosomal subunit processome, variant 1
CPX-1607, Small ribosomal subunit processome, variant 2
CPX-1608, Small ribosomal subunit processome, variant 3
DIPiDIP-5283N
IntActiP33201, 30 interactors
MINTiP33201
STRINGi4932.YKL009W

PTM databases

iPTMnetiP33201

Proteomic databases

MaxQBiP33201
PaxDbiP33201
PRIDEiP33201

Genome annotation databases

EnsemblFungiiYKL009W_mRNA; YKL009W; YKL009W
GeneIDi853860
KEGGisce:YKL009W

Organism-specific databases

SGDiS000001492, MRT4
VEuPathDBiFungiDB:YKL009W

Phylogenomic databases

eggNOGiKOG0816, Eukaryota
GeneTreeiENSGT00940000168261
HOGENOMiCLU_071690_0_0_1
InParanoidiP33201
OMAiLEWAENY

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P33201
RNActiP33201, protein

Family and domain databases

CDDicd05796, Ribosomal_P0_like, 1 hit
Gene3Di3.30.70.1730, 1 hit
3.90.105.20, 1 hit
InterProiView protein in InterPro
IPR033867, Mrt4
IPR043141, Ribosomal_L10-like_sf
IPR001790, Ribosomal_L10P
IPR043164, RL10_insert_sf
IPR040637, RL10P_insert
PfamiView protein in Pfam
PF00466, Ribosomal_L10, 1 hit
PF17777, RL10P_insert, 1 hit
SUPFAMiSSF160369, SSF160369, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMRT4_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P33201
Secondary accession number(s): D6VXS7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: September 29, 2021
This is version 169 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families
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