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UniProtKB - P33174 (KIF4_MOUSE)

Entry version 168 (10 Feb 2021)
Sequence version 3 (27 Jul 2011)
Previous versions | rss
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Protein

Chromosome-associated kinesin KIF4

Gene

Kif4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Iron-sulfur (Fe-S) cluster binding motor protein that has a role in chromosome segregation during mitosis (By similarity). Required for mitotic chromosomal positioning and bipolar spindle stabilization.By similarity1 Publication

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

[2Fe-2S] clusterBy similarity, [4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster (By similarity). In the presence of oxygen, the [4Fe-4S] cluster may be converted to [2Fe-2S] (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi88 – 95ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Motor protein
LigandATP-binding, Iron, Iron-sulfur, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-2132295, MHC class II antigen presentation
R-MMU-437239, Recycling pathway of L1
R-MMU-6811434, COPI-dependent Golgi-to-ER retrograde traffic
R-MMU-983189, Kinesins

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chromosome-associated kinesin KIF4
Alternative name(s):
Chromokinesin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Kif4
Synonyms:Kif4a, Kns4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:108389, Kif4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Cytoskeleton, Microtubule, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001254381 – 1231Chromosome-associated kinesin KIF4Add BLAST1231

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei395PhosphoserineCombined sources1
Modified residuei800PhosphothreonineCombined sources1
Modified residuei802PhosphoserineCombined sources1
Modified residuei811PhosphoserineCombined sources1
Modified residuei816PhosphoserineCombined sources1
Modified residuei1224PhosphoserineCombined sources1
Modified residuei1230PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P33174

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P33174

MaxQB - The MaxQuant DataBase

More...MaxQBi		P33174

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P33174

PeptideAtlas

More...PeptideAtlasi		P33174

PRoteomics IDEntifications database

More...PRIDEi		P33174

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P33174

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P33174

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P33174

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in pyramidal cells in juvenile hippocampus, granular cells in juvenile cerebellar cortex and in adult spleen.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000034311, Expressed in primary oocyte and 220 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P33174, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		200944, 38 interactors

Protein interaction database and analysis system

More...IntActi		P33174, 29 interactors

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000048383

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P33174, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11231
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P33174

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 337Kinesin motorPROSITE-ProRule annotationAdd BLAST329

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1001 – 1231GlobularAdd BLAST231

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili351 – 1000Sequence analysisAdd BLAST650

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Chromokinesin subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0244, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000158195

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_001485_4_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P33174

Identification of Orthologs from Complete Genome Data

More...OMAi		GCLELGN

Database of Orthologous Groups

More...OrthoDBi		369179at2759

TreeFam database of animal gene trees

More...TreeFami		TF105224

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.850.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR019821, Kinesin_motor_CS
IPR001752, Kinesin_motor_dom
IPR036961, Kinesin_motor_dom_sf
IPR027417, P-loop_NTPase
IPR033467, Tesmin/TSO1-like_CXC

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00225, Kinesin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00380, KINESINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01114, CXC, 1 hit
SM00129, KISc, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00411, KINESIN_MOTOR_1, 1 hit
PS50067, KINESIN_MOTOR_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P33174-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKEEVKGIPV RVALRCRPLV SKEIKEGCQT CLSFVPGEPQ VVVGNDKSFT 
        60         70         80         90        100
YDFVFDPSTE QEEVFNTAVA PLIKGVFKGY NATVLAYGQT GSGKTYSMGG 
       110        120        130        140        150
AYTAEQEHDS AIGVIPRVIQ LLFKEINKKS DFEFTLKVSY LEIYNEEILD 
       160        170        180        190        200
LLCSSREKAT QINIREDPKE GIKIVGLTEK TVLVASDTVS CLEQGNNSRT 
       210        220        230        240        250
VASTAMNSQS SRSHAIFTIS IEQRKKNDKN SSFRSKLHLV DLAGSERQKK 
       260        270        280        290        300
TKAEGDRLRE GININRGLLC LGNVISALGD DKKGNFVPYR DSKLTRLLQD 
       310        320        330        340        350
SLGGNSHTLM IACVSPADSN LEETLNTLRY ADRARKIKNK PIINIDPQAA 
       360        370        380        390        400
ELNHLKQQVQ QLQILLLQAH GGTLPGDINV EPSENLQSLM EKNQSLVEEN 
       410        420        430        440        450
EKLSRGLSEA AGQTAQMLER IILTEQANEK MNAKLEELRR HAACKVDLQK 
       460        470        480        490        500
LVETLEDQEL KENIEIICNL QQVIAQLSDE AAACMTATID TAGEADTQVQ 
       510        520        530        540        550
SSPDTSRSSD VFSTQHALRQ AQMSKELIEL NKALALKEAL AKKMTQNDNQ 
       560        570        580        590        600
LQPIQFQYQD NIKNLESEVL SLQREKEELV LELQTAKKDA NQAKLSERRR 
       610        620        630        640        650
KRLQELEGQI ADLKKKLQEQ SKLLKLKEST EHTVSKLNQE IRMMKNQRVQ 
       660        670        680        690        700
LMRQMKEDAE KFRQWKQQKD KEVIQLKERD RKRQYELLKL ERNFQKQSNV 
       710        720        730        740        750
LRRKTEEAAA ANKRLKDALQ KQKEVAEKRK ETQSRGMEST AARMKNWLGN 
       760        770        780        790        800
EIEVMVSTEE AKRHLNGLLE ERKILAQDVA QLKEKRESGE NPPLKLRRRT 
       810        820        830        840        850
FSYDEIHGQD SGAEDSIAKQ IESLETELEL RSAQIADLQQ KLLDAESEDR 
       860        870        880        890        900
PKQRWESIAT ILEAKCAIKY LVGELVSSKI LVSKLESSLN QSKASCIDVQ 
       910        920        930        940        950
KMLFEEQNHF AKIETELKEE LVKVEQQHQE KVLYLLSQLQ QSQMTEKQLE 
       960        970        980        990       1000
ESVSEKEQQL LSTLKCQEEE LRKMQEVCEQ NQQLLQENSA IKQKLTLLQV 
      1010       1020       1030       1040       1050
ASKQKPHLTR NIFQSPDSSF EYIPPKPKPC RIKEKCLEQS FAVEGLQYYS 
      1060       1070       1080       1090       1100
EPSVAEQDNE DSDDHADEEW IPTKLVKVSK KSIQGCSCKG WCGNKQCGCR 
      1110       1120       1130       1140       1150
KQKSDCNVSC SCDPTKCRNR HQNQDNSDAI ELNQDSENSF KLEDPTEVTS 
      1160       1170       1180       1190       1200
GLSFFHPICA TPSSKILKEM CDADQVQLKQ PVFVSSSDHP ELKSIASESQ 
      1210       1220       1230 
ENKAIGKKKK RALASNTSFF SGCSPIQEES H
Length:1,231
Mass (Da):139,519
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAA3C5E2E52678DE7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti112I → S (PubMed:19468303).Curated1
Sequence conflicti1044 – 1045EG → GE in BAA02167 (PubMed:7929562).Curated2
Sequence conflicti1182V → M in BAA02167 (PubMed:7929562).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
D12646 mRNA Translation: BAA02167.1
BX005480 Genomic DNA No translation available.
BX276129 Genomic DNA No translation available.
CH466564 Genomic DNA Translation: EDL14171.1
BC050946 mRNA Translation: AAH50946.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS30305.1

Protein sequence database of the Protein Information Resource

More...PIRi		A54803

NCBI Reference Sequences

More...RefSeqi		NP_032472.2, NM_008446.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000048962; ENSMUSP00000048383; ENSMUSG00000034311

Database of genes from NCBI RefSeq genomes

More...GeneIDi		16571

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:16571

UCSC genome browser

More...UCSCi		uc009twh.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12646 mRNA Translation: BAA02167.1
BX005480 Genomic DNA No translation available.
BX276129 Genomic DNA No translation available.
CH466564 Genomic DNA Translation: EDL14171.1
BC050946 mRNA Translation: AAH50946.1
CCDSiCCDS30305.1
PIRiA54803
RefSeqiNP_032472.2, NM_008446.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3ZFCX-ray1.80A1-344[»]
3ZFDX-ray1.71A1-344[»]
SMRiP33174
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi200944, 38 interactors
IntActiP33174, 29 interactors
STRINGi10090.ENSMUSP00000048383

PTM databases

iPTMnetiP33174
PhosphoSitePlusiP33174
SwissPalmiP33174

Proteomic databases

EPDiP33174
jPOSTiP33174
MaxQBiP33174
PaxDbiP33174
PeptideAtlasiP33174
PRIDEiP33174

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		27394, 212 antibodies

Genome annotation databases

EnsembliENSMUST00000048962; ENSMUSP00000048383; ENSMUSG00000034311
GeneIDi16571
KEGGimmu:16571
UCSCiuc009twh.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		16571
MGIiMGI:108389, Kif4

Phylogenomic databases

eggNOGiKOG0244, Eukaryota
GeneTreeiENSGT00940000158195
HOGENOMiCLU_001485_4_1_1
InParanoidiP33174
OMAiGCLELGN
OrthoDBi369179at2759
TreeFamiTF105224

Enzyme and pathway databases

ReactomeiR-MMU-2132295, MHC class II antigen presentation
R-MMU-437239, Recycling pathway of L1
R-MMU-6811434, COPI-dependent Golgi-to-ER retrograde traffic
R-MMU-983189, Kinesins

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		16571, 7 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Kif4, mouse

Protein Ontology

More...PROi		PR:P33174
RNActiP33174, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000034311, Expressed in primary oocyte and 220 other tissues
GenevisibleiP33174, MM

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR019821, Kinesin_motor_CS
IPR001752, Kinesin_motor_dom
IPR036961, Kinesin_motor_dom_sf
IPR027417, P-loop_NTPase
IPR033467, Tesmin/TSO1-like_CXC
PfamiView protein in Pfam
PF00225, Kinesin, 1 hit
PRINTSiPR00380, KINESINHEAVY
SMARTiView protein in SMART
SM01114, CXC, 1 hit
SM00129, KISc, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411, KINESIN_MOTOR_1, 1 hit
PS50067, KINESIN_MOTOR_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKIF4_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P33174
Secondary accession number(s): Q80YP3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: July 27, 2011
Last modified: February 10, 2021
This is version 168 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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