UniProtKB - P33135 (FLIR_ECOLI)
Protein
Flagellar biosynthetic protein FliR
Gene
fliR
Organism
Escherichia coli (strain K12)
Status
Functioni
Role in flagellar biosynthesis.
GO - Biological processi
- bacterial-type flagellum assembly Source: InterPro
- protein targeting Source: InterPro
Enzyme and pathway databases
BioCyci | EcoCyc:EG11977-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Flagellar biosynthetic protein FliR |
Gene namesi | Name:fliR Synonyms:flaP Ordered Locus Names:b1950, JW1934 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane 1 Publication; Multi-pass membrane protein 1 Publication
- Bacterial flagellum basal body 1 Publication
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 13 – 33 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 45 – 65 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 66 – 86 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 90 – 110 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 131 – 151 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 184 – 204 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 213 – 233 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 235 – 255 | HelicalSequence analysisAdd BLAST | 21 |
GO - Cellular componenti
- bacterial-type flagellum basal body Source: UniProtKB-SubCell
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Bacterial flagellum, Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000192055 | 1 – 261 | Flagellar biosynthetic protein FliRAdd BLAST | 261 |
Proteomic databases
PaxDbi | P33135 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261046, 276 interactors |
ComplexPortali | CPX-5885, Flagellar export complex |
IntActi | P33135, 4 interactors |
STRINGi | 511145.b1950 |
Family & Domainsi
Sequence similaritiesi
Belongs to the FliR/MopE/SpaR family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG1684, Bacteria |
HOGENOMi | CLU_063626_4_0_6 |
InParanoidi | P33135 |
PhylomeDBi | P33135 |
Family and domain databases
InterProi | View protein in InterPro IPR006303, FliR IPR002010, T3SS_IM_R |
PANTHERi | PTHR30065, PTHR30065, 1 hit |
Pfami | View protein in Pfam PF01311, Bac_export_1, 1 hit |
PRINTSi | PR00953, TYPE3IMRPROT |
TIGRFAMsi | TIGR01400, fliR, 1 hit |
i Sequence
Sequence statusi: Complete.
P33135-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLQVTSEQWL SWLNLYFWPL LRVLALISTA PILSERSVPK RVKLGLAMMI
60 70 80 90 100
TFAIAPSLPA NDVPVFSFFA LWLAVQQILI GIALGFTMQF AFAAVRTAGE
110 120 130 140 150
IIGLQMGLSF ATFVDPASHL NMPVLARIMD MLALLLFLTF NGHLWLISLL
160 170 180 190 200
VDTFHTLPIG GEPLNSNAFL ALTKAGSLIF LNGLMLALPL ITLLLTLNLA
210 220 230 240 250
LGLLNRMAPQ LSIFVIGFPL TLTVGISLMA ALMPLIAPFC EHLFSEIFNL
260
LADIISELPL I
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 223 | T → A in AAC36861 (PubMed:8282695).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L22182 Genomic DNA Translation: AAC36861.1 U00096 Genomic DNA Translation: AAC75017.1 AP009048 Genomic DNA Translation: BAA15775.1 |
PIRi | C64959 |
RefSeqi | NP_416460.1, NC_000913.3 WP_000942319.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC75017; AAC75017; b1950 BAA15775; BAA15775; BAA15775 |
GeneIDi | 946464 |
KEGGi | ecj:JW1934 eco:b1950 |
PATRICi | fig|1411691.4.peg.301 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L22182 Genomic DNA Translation: AAC36861.1 U00096 Genomic DNA Translation: AAC75017.1 AP009048 Genomic DNA Translation: BAA15775.1 |
PIRi | C64959 |
RefSeqi | NP_416460.1, NC_000913.3 WP_000942319.1, NZ_LN832404.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261046, 276 interactors |
ComplexPortali | CPX-5885, Flagellar export complex |
IntActi | P33135, 4 interactors |
STRINGi | 511145.b1950 |
Proteomic databases
PaxDbi | P33135 |
Genome annotation databases
EnsemblBacteriai | AAC75017; AAC75017; b1950 BAA15775; BAA15775; BAA15775 |
GeneIDi | 946464 |
KEGGi | ecj:JW1934 eco:b1950 |
PATRICi | fig|1411691.4.peg.301 |
Organism-specific databases
EchoBASEi | EB1920 |
Phylogenomic databases
eggNOGi | COG1684, Bacteria |
HOGENOMi | CLU_063626_4_0_6 |
InParanoidi | P33135 |
PhylomeDBi | P33135 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11977-MONOMER |
Miscellaneous databases
PROi | PR:P33135 |
Family and domain databases
InterProi | View protein in InterPro IPR006303, FliR IPR002010, T3SS_IM_R |
PANTHERi | PTHR30065, PTHR30065, 1 hit |
Pfami | View protein in Pfam PF01311, Bac_export_1, 1 hit |
PRINTSi | PR00953, TYPE3IMRPROT |
TIGRFAMsi | TIGR01400, fliR, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FLIR_ECOLI | |
Accessioni | P33135Primary (citable) accession number: P33135 Secondary accession number(s): P76327 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1993 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 10, 2021 | |
This is version 145 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families