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UniProtKB - P33024 (PSUT_ECOLI)

Entry version 152 (10 Feb 2021)
Sequence version 1 (01 Feb 1994)
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Protein

Putative pseudouridine transporter

Gene

psuT

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Could be involved in pseudouridine transport.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:YEIM-MONOMER

Protein family/group databases

Transport Classification Database

More...TCDBi		2.A.41.2.9, the concentrative nucleoside transporter (cnt) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative pseudouridine transporter
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:psuT
Synonyms:pscT, yeiM
Ordered Locus Names:b2164, JW2151
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 2PeriplasmicSequence analysis2
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3 – 23HelicalSequence analysisAdd BLAST21
Topological domaini24 – 31CytoplasmicSequence analysis8
Transmembranei32 – 52HelicalSequence analysisAdd BLAST21
Topological domaini53 – 104PeriplasmicSequence analysisAdd BLAST52
Transmembranei105 – 125HelicalSequence analysisAdd BLAST21
Topological domaini126 – 172CytoplasmicSequence analysisAdd BLAST47
Transmembranei173 – 193HelicalSequence analysisAdd BLAST21
Topological domaini194 – 196PeriplasmicSequence analysis3
Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Topological domaini218 – 268CytoplasmicSequence analysisAdd BLAST51
Transmembranei269 – 289HelicalSequence analysisAdd BLAST21
Topological domaini290 – 352PeriplasmicSequence analysisAdd BLAST63
Transmembranei353 – 373HelicalSequence analysisAdd BLAST21
Topological domaini374 – 394CytoplasmicSequence analysisAdd BLAST21
Transmembranei395 – 415HelicalSequence analysisAdd BLAST21
Topological domaini416PeriplasmicSequence analysis1

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000704581 – 416Putative pseudouridine transporterAdd BLAST416

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P33024

PRoteomics IDEntifications database

More...PRIDEi		P33024

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4260636, 134 interactors

Database of interacting proteins

More...DIPi		DIP-11925N

Protein interaction database and analysis system

More...IntActi		P33024, 2 interactors

STRING: functional protein association networks

More...STRINGi		511145.b2164

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P33024

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG1972, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_016813_4_2_6

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P33024

Database for complete collections of gene phylogenies

More...PhylomeDBi		P33024

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR008276, C_nuclsd_transpt
IPR018270, C_nuclsd_transpt_met_bac
IPR011657, CNT_C_dom
IPR002668, CNT_N_dom

The PANTHER Classification System

More...PANTHERi		PTHR10590, PTHR10590, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF07662, Nucleos_tra2_C, 1 hit
PF01773, Nucleos_tra2_N, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00804, nupC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P33024-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDIMRSVVGM VVLLAIAFLL SVNKKSISLR TVGAALLLQI AIGGIMLYFP 
        60         70         80         90        100
PGKWAVEQAA LGVHKVMSYS DAGSAFIFGS LVGPKMDVLF DGAGFIFAFR 
       110        120        130        140        150
VLPAIIFVTA LISLLYYIGV MGLLIRILGS IFQKALNISK IESFVAVTTI 
       160        170        180        190        200
FLGQNEIPAI VKPFIDRMNR NELFTAICSG MASIAGSMMI GYAGMGVPID 
       210        220        230        240        250
YLLAASLMAI PGGILFARIL SPATEPSQVT FENLSFSETP PKSFIEAAAS 
       260        270        280        290        300
GAMTGLKIAA GVATVVMAFV AIIALINGII GGIGGWFGFA NASLESIFGY 
       310        320        330        340        350
VLAPLAWIMG VDWSDANLAG SLIGQKLAIN EFVAYLSFSP YLQTGGTLEV 
       360        370        380        390        400
KTIAIISFAL CGFANFGSIG VVVGAFSAIS PKRAPEIAQL GLRALAAATL 
       410 
SNLMSATIAG FFIGLA
Length:416
Mass (Da):43,432
Last modified:February 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i60CCE29DBF46722A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U00007 Genomic DNA Translation: AAA60518.1
U00096 Genomic DNA Translation: AAC75225.1
AP009048 Genomic DNA Translation: BAE76641.1

Protein sequence database of the Protein Information Resource

More...PIRi		C64985

NCBI Reference Sequences

More...RefSeqi		NP_416669.1, NC_000913.3
WP_000353878.1, NZ_SSZK01000027.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC75225; AAC75225; b2164
BAE76641; BAE76641; BAE76641

Database of genes from NCBI RefSeq genomes

More...GeneIDi		57729676
946671

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW2151
eco:b2164

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.75

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00007 Genomic DNA Translation: AAA60518.1
U00096 Genomic DNA Translation: AAC75225.1
AP009048 Genomic DNA Translation: BAE76641.1
PIRiC64985
RefSeqiNP_416669.1, NC_000913.3
WP_000353878.1, NZ_SSZK01000027.1

3D structure databases

SMRiP33024
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi4260636, 134 interactors
DIPiDIP-11925N
IntActiP33024, 2 interactors
STRINGi511145.b2164

Protein family/group databases

TCDBi2.A.41.2.9, the concentrative nucleoside transporter (cnt) family

Proteomic databases

PaxDbiP33024
PRIDEiP33024

Genome annotation databases

EnsemblBacteriaiAAC75225; AAC75225; b2164
BAE76641; BAE76641; BAE76641
GeneIDi57729676
946671
KEGGiecj:JW2151
eco:b2164
PATRICifig|1411691.4.peg.75

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB1967

Phylogenomic databases

eggNOGiCOG1972, Bacteria
HOGENOMiCLU_016813_4_2_6
InParanoidiP33024
PhylomeDBiP33024

Enzyme and pathway databases

BioCyciEcoCyc:YEIM-MONOMER

Miscellaneous databases

Protein Ontology

More...PROi		PR:P33024

Family and domain databases

InterProiView protein in InterPro
IPR008276, C_nuclsd_transpt
IPR018270, C_nuclsd_transpt_met_bac
IPR011657, CNT_C_dom
IPR002668, CNT_N_dom
PANTHERiPTHR10590, PTHR10590, 1 hit
PfamiView protein in Pfam
PF07662, Nucleos_tra2_C, 1 hit
PF01773, Nucleos_tra2_N, 1 hit
TIGRFAMsiTIGR00804, nupC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPSUT_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P33024
Secondary accession number(s): Q2MAR5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: February 10, 2021
This is version 152 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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