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Protein

Probable alcohol dehydrogenase

Gene

terPD

Organism
Pseudomonas sp.
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

A primary alcohol + NAD+ = an aldehyde + NADH.
A secondary alcohol + NAD+ = a ketone + NADH.

Cofactori

Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi18Zinc 1; catalyticBy similarity1
Metal bindingi39Zinc 1; catalyticBy similarity1
Metal bindingi68Zinc 2By similarity1
Metal bindingi71Zinc 2By similarity1
Metal bindingi74Zinc 2By similarity1
Metal bindingi82Zinc 2By similarity1
Metal bindingi149Zinc 1; catalyticBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandMetal-binding, NAD, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Probable alcohol dehydrogenase (EC:1.1.1.1)
Gene namesi
Name:terPD
OrganismiPseudomonas sp.
Taxonomic identifieri306 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001607511 – 319Probable alcohol dehydrogenaseAdd BLAST319

Structurei

3D structure databases

ProteinModelPortaliP33010
SMRiP33010
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR013149 ADH_C
IPR013154 ADH_N
IPR002328 ADH_Zn_CS
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF08240 ADH_N, 1 hit
PF00107 ADH_zinc_N, 1 hit
SUPFAMiSSF50129 SSF50129, 1 hit
SSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00059 ADH_ZINC, 1 hit

Sequencei

Sequence statusi: Complete.

P33010-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRREMMKCL FVSESCVCHT DLAIKDGVLP FPLPAVLGHE GSGIVEAVGP
60 70 80 90 100
GVKHLKPGDA VVMTFASCGH CASCEHERPS YCLDFGAQNY SAQRADGPVL
110 120 130 140 150
LSQGDEVISG FFFGQSSFSS MAMAREHNLV KIDALVDDAP IELLGPLGCG
160 170 180 190 200
VQTGAGAVMI SLDVRAGRSF LVLGGGAVGL SAVMAAKLRG CSRIIVSEPS
210 220 230 240 250
AAKREQALAL GATEVIDPLN ENLVERVQQI TEGQGCDYAL ECTGLVSVME
260 270 280 290 300
QAIDSMAMRG QLAVVGVPPK LDATAAVSPL ALIQKGLKLM GVIEGDSCRV
310
YSSTSCTRSS RLGVFRSPR
Length:319
Mass (Da):33,401
Last modified:October 1, 1993 - v1
Checksum:i0478906D3C21A614
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M91440 Genomic DNA Translation: AAA25994.1
PIRiB42971

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M91440 Genomic DNA Translation: AAA25994.1
PIRiB42971

3D structure databases

ProteinModelPortaliP33010
SMRiP33010
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR013149 ADH_C
IPR013154 ADH_N
IPR002328 ADH_Zn_CS
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF08240 ADH_N, 1 hit
PF00107 ADH_zinc_N, 1 hit
SUPFAMiSSF50129 SSF50129, 1 hit
SSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00059 ADH_ZINC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTERPD_PSESP
AccessioniPrimary (citable) accession number: P33010
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: November 22, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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