UniProtKB - P32907 (ATO2_YEAST)
Protein
Ammonia transport outward protein 2
Gene
ATO2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Transporter protein required for ammonia export. Involved in acetate resistance.2 Publications
GO - Molecular functioni
- acetate transmembrane transporter activity Source: GO_Central
- ammonium transmembrane transporter activity Source: SGD
GO - Biological processi
- ammonium transport Source: SGD
- nitrogen utilization Source: SGD
Keywordsi
Biological process | Ammonia transport, Ion transport, Transport |
Protein family/group databases
TCDBi | 2.A.96.1.7, the acetate uptake transporter (acetr) family |
Names & Taxonomyi
Protein namesi | Recommended name: Ammonia transport outward protein 2 |
Gene namesi | Name:ATO2 Synonyms:FUN34 Ordered Locus Names:YNR002C ORF Names:N2029 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000005285, ATO2 |
VEuPathDBi | FungiDB:YNR002C |
Subcellular locationi
Plasma membrane
- Cell membrane 1 Publication; Multi-pass membrane protein 1 Publication
Note: Localizes to large detergent resistant patches of the cell membrane (DRM) enriched in ergosterol and sphingolipids.
Mitochondrion
- mitochondrion Source: SGD
Plasma Membrane
- plasma membrane Source: SGD
Vacuole
- fungal-type vacuole Source: SGD
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 2 – 86 | ExtracellularSequence analysisAdd BLAST | 85 | |
Transmembranei | 87 – 107 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 108 – 119 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 120 – 140 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 141 – 150 | ExtracellularSequence analysis | 10 | |
Transmembranei | 151 – 171 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 172 – 184 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 185 – 205 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 206 – 207 | ExtracellularSequence analysis | 2 | |
Transmembranei | 208 – 228 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 229 – 238 | CytoplasmicSequence analysis | 10 | |
Transmembranei | 239 – 259 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 260 – 282 | ExtracellularSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedCombined sources | |||
ChainiPRO_0000135701 | 2 – 282 | Ammonia transport outward protein 2Add BLAST | 281 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylserineCombined sources | 1 | |
Modified residuei | 2 | PhosphoserineCombined sources | 1 | |
Modified residuei | 7 | PhosphoserineCombined sources | 1 | |
Modified residuei | 21 | PhosphoserineCombined sources | 1 | |
Modified residuei | 22 | PhosphoserineCombined sources | 1 | |
Modified residuei | 28 | PhosphoserineCombined sources | 1 | |
Modified residuei | 40 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
PaxDbi | P32907 |
PTM databases
iPTMneti | P32907 |
Expressioni
Inductioni
By external ammonia.1 Publication
Interactioni
Protein-protein interaction databases
BioGRIDi | 35828, 42 interactors |
DIPi | DIP-7904N |
STRINGi | 4932.YNR002C |
Miscellaneous databases
RNActi | P32907, protein |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QUJS, Eukaryota |
GeneTreei | ENSGT00940000176398 |
HOGENOMi | CLU_051062_0_0_1 |
InParanoidi | P32907 |
OMAi | GAFWATW |
Family and domain databases
InterProi | View protein in InterPro IPR000791, Gpr1/Fun34/SatP |
Pfami | View protein in Pfam PF01184, Gpr1_Fun34_YaaH, 1 hit |
PROSITEi | View protein in PROSITE PS01114, GPR1_FUN34_YAAH, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P32907-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDREQSSGN TAFENPKALD SSEGEFISEN NDQSRHSQES ICKIYTAGKN
60 70 80 90 100
NEYIYIGRQK FLRDDLFEAF GGTLNPGLAP APVHKFANPA PLGLSGFALT
110 120 130 140 150
TFVLSMFNAR AQGITIPNVV VGCAMFYGGL VQLIAGIWEI ALENTFGGTA
160 170 180 190 200
LCSFGGFWLS FGAIYIPWFG ILDAYKDKES DLGNALGFYL LGWALFTFGL
210 220 230 240 250
SVCTMKSTIM FFALFFLLAV TFLLLSIANF TGEVGVTRAG GVLGVIVAFI
260 270 280
AWYNAYAGIA TRQNSYIMVH PFALPSNDKV FF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X63746 Genomic DNA Translation: CAA45279.1 X77395 Genomic DNA Translation: CAA54571.1 Z71617 Genomic DNA Translation: CAA96278.1 BK006947 Genomic DNA Translation: DAA10544.1 |
PIRi | S31258 |
RefSeqi | NP_014399.3, NM_001183179.3 |
Genome annotation databases
EnsemblFungii | YNR002C_mRNA; YNR002C; YNR002C |
GeneIDi | 855736 |
KEGGi | sce:YNR002C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X63746 Genomic DNA Translation: CAA45279.1 X77395 Genomic DNA Translation: CAA54571.1 Z71617 Genomic DNA Translation: CAA96278.1 BK006947 Genomic DNA Translation: DAA10544.1 |
PIRi | S31258 |
RefSeqi | NP_014399.3, NM_001183179.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 35828, 42 interactors |
DIPi | DIP-7904N |
STRINGi | 4932.YNR002C |
Protein family/group databases
TCDBi | 2.A.96.1.7, the acetate uptake transporter (acetr) family |
PTM databases
iPTMneti | P32907 |
Proteomic databases
PaxDbi | P32907 |
Genome annotation databases
EnsemblFungii | YNR002C_mRNA; YNR002C; YNR002C |
GeneIDi | 855736 |
KEGGi | sce:YNR002C |
Organism-specific databases
SGDi | S000005285, ATO2 |
VEuPathDBi | FungiDB:YNR002C |
Phylogenomic databases
eggNOGi | ENOG502QUJS, Eukaryota |
GeneTreei | ENSGT00940000176398 |
HOGENOMi | CLU_051062_0_0_1 |
InParanoidi | P32907 |
OMAi | GAFWATW |
Miscellaneous databases
PROi | PR:P32907 |
RNActi | P32907, protein |
Family and domain databases
InterProi | View protein in InterPro IPR000791, Gpr1/Fun34/SatP |
Pfami | View protein in Pfam PF01184, Gpr1_Fun34_YaaH, 1 hit |
PROSITEi | View protein in PROSITE PS01114, GPR1_FUN34_YAAH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ATO2_YEAST | |
Accessioni | P32907Primary (citable) accession number: P32907 Secondary accession number(s): D6W1H8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1993 |
Last sequence update: | October 1, 1993 | |
Last modified: | February 10, 2021 | |
This is version 145 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - SIMILARITY comments
Index of protein domains and families - Yeast chromosome XIV
Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names