SSO1

Functionⁱ

Required for vesicle fusion with the plasma membrane.

Miscellaneous

Present with 450 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functionⁱ

phosphatidic acid binding
Source: SGD
Inferred from direct assayⁱ
- 19502581
phosphatidylinositol-3,4-bisphosphate binding
Source: SGD
Inferred from direct assayⁱ
- 19502581
phosphatidylinositol-3,5-bisphosphate binding
Source: SGD
Inferred from direct assayⁱ
- 19502581
phosphatidylinositol-4,5-bisphosphate binding
Source: SGD
Inferred from direct assayⁱ
- 19502581
SNAP receptor activity
Source: SGD
Inferred from direct assayⁱ
- 16339720
SNARE binding
Source: CAFA
Inferred from physical interactionⁱ
- 10048921
- 9326367

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

ascospore formation
Source: SGD
Inferred from mutant phenotypeⁱ
- 11839791
ascospore-type prospore assembly
Source: SGD
Inferred from mutant phenotypeⁱ
- 16554438
- 19502581
exocytosis Source: GO_Central
intracellular protein transport Source: GO_Central
SNARE complex assembly
Source: CAFA
Inferred from mutant phenotypeⁱ
- 10048921
- 9326367
vesicle docking Source: GO_Central
vesicle fusion
Source: SGD
Inferred from direct assayⁱ
- 11001046

View the complete GO annotation on QuickGO ...

Enzyme and pathway databases

BioCycⁱ	YEAST:G3O-34119-MONOMER
Reactomeⁱ	R-SCE-114516 Disinhibition of SNARE formation

Protein family/group databases

TCDBⁱ	8.A.91.1.5 the syntaxin (syntaxin) family

TCDBⁱ

8.A.91.1.5 the syntaxin (syntaxin) family

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Protein SSO1
Gene namesⁱ	Name:SSO1 Ordered Locus Names:YPL232W ORF Names:P1405
Organismⁱ	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifierⁱ	559292 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae
Proteomesⁱ	UP000002311 Componentⁱ: Chromosome XVI

Organism-specific databases

EuPathDBⁱ	FungiDB:YPL232W
Saccharomyces Genome Database More...SGDⁱ	S000006153 SSO1

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 265	CytoplasmicSequence analysisAdd BLAST	265
Transmembraneⁱ	266 – 287	Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST	22
Topological domainⁱ	288 – 290	ExtracellularSequence analysis	3

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000210274	1 – 290	Protein SSO1Add BLAST		290

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P32867
PaxDbⁱ	P32867
PRIDEⁱ	P32867

PTM databases

iPTMnetⁱ	P32867
SwissPalmⁱ	P32867

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
SEC22	P22214	2	EBI-2206525,EBI-16577
SEC9	P40357	14	EBI-2206525,EBI-16904
SNC2	P33328	2	EBI-2206525,EBI-17512

GO - Molecular functionⁱ

SNAP receptor activity
Source: SGD
Inferred from direct assayⁱ
- 16339720
SNARE binding
Source: CAFA
Inferred from physical interactionⁱ
- 10048921
- 9326367

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	35930, 130 interactors
ComplexPortalⁱ	CPX-1365 Vesicular t-SNARE complex, SSO1 variant
Database of interacting proteins More...DIPⁱ	DIP-2494N
IntActⁱ	P32867, 7 interactors
STRINGⁱ	4932.YPL232W

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	31 – 64	Combined sources	34
Helixⁱ	70 – 104	Combined sources	35
Turnⁱ	105 – 107	Combined sources	3
Helixⁱ	109 – 151	Combined sources	43
Helixⁱ	157 – 163	Combined sources	7
Helixⁱ	166 – 176	Combined sources	11
Helixⁱ	190 – 256	Combined sources	67

Show more details

3D structure databases

ProteinModelPortalⁱ	P32867
SMRⁱ	P32867
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	P32867

EvolutionaryTraceⁱ

P32867

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	190 – 252	t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST		63

Sequence similaritiesⁱ

Belongs to the syntaxin family.Curated

Keywords - Domainⁱ

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119200
HOGENOMⁱ	HOG000246774
InParanoidⁱ	P32867
KEGG Orthology (KO) More...KOⁱ	K08486
OMAⁱ	CRKNDDG
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C42X0

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00179 SynN, 1 hit
InterProⁱ	View protein in InterPro IPR010989 SNARE IPR006012 Syntaxin/epimorphin_CS IPR006011 Syntaxin_N IPR000727 T_SNARE_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF05739 SNARE, 1 hit PF00804 Syntaxin, 1 hit
SMARTⁱ	View protein in SMART SM00503 SynN, 1 hit SM00397 t_SNARE, 1 hit
SUPFAMⁱ	SSF47661 SSF47661, 1 hit
PROSITEⁱ	View protein in PROSITE PS00914 SYNTAXIN, 1 hit PS50192 T_SNARE, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P32867-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSYNNPYQLE TPFEESYELD EGSSAIGAEG HDFVGFMNKI SQINRDLDKY 
        60         70         80         90        100
DHTINQVDSL HKRLLTEVNE EQASHLRHSL DNFVAQATDL QFKLKNEIKS 
       110        120        130        140        150
AQRDGIHDTN KQAQAENSRQ RFLKLIQDYR IVDSNYKEEN KEQAKRQYMI 
       160        170        180        190        200
IQPEATEDEV EAAISDVGGQ QIFSQALLNA NRRGEAKTAL AEVQARHQEL 
       210        220        230        240        250
LKLEKSMAEL TQLFNDMEEL VIEQQENVDV IDKNVEDAQL DVEQGVGHTD 
       260        270        280        290
KAVKSARKAR KNKIRCWLIV FAIIVVVVVV VVVPAVVKTR

Length:290

Mass (Da):33,106

Last modified:February 1, 1995 - v2

Checksum:ⁱ6E4C6D35C3CD9D94

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	97	E → G no nucleotide entry (PubMed:2900835).Curated		1
Sequence conflictⁱ	105	G → V no nucleotide entry (PubMed:2900835).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X67729 mRNA Translation: CAA47959.1 X76890 Genomic DNA Translation: CAA54217.1 X94561 Genomic DNA Translation: CAA64255.1 Z73588 Genomic DNA Translation: CAA97949.1 J03936 Genomic DNA No translation available. BK006949 Genomic DNA Translation: DAA11204.1
PIRⁱ	S39569
NCBI Reference Sequences More...RefSeqⁱ	NP_015092.1, NM_001184046.1

Genome annotation databases

EnsemblFungiⁱ	YPL232W; YPL232W; YPL232W
GeneIDⁱ	855844
KEGGⁱ	sce:YPL232W

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P32867	K7_Sso1p		YEASK		290	UniRef100_P32867
Sso1p		YEASC		290
Sso1p		YEASZ		142
UPI00017545C3		YEASX		69

Protein	Similar proteins		Species	Score	Length	Source
P32867	K7_Sso1p		YEASK		290	UniRef90_P32867
Sso1p		YEASC		290
Sso1p		YEASZ		142
SSO1-like protein		SACEU		290
Sso1p		YEASB		290
+15

Protein	Similar proteins		Species	Score	Length	Source
P32867	K7_Sso1p		YEASK		290	UniRef50_P32867
Sso1p		YEASC		290
Sso1p		YEASZ		142
Protein SSO1		YEAS1		290
Sso1p		YEAS8		290
+38

Entry informationⁱ

Entry nameⁱ	SSO1_YEAST
Accessionⁱ	P32867Primary (citable) accession number: P32867 Secondary accession number(s): D6W3D8
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
	Last sequence update:	February 1, 1995
	Last modified:	September 12, 2018
	This is version 154 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Fungal Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P32867 (SSO1_YEAST)

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Protein SSO1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Plasma Membrane

Vacuole

Other locations

Topology

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ