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UniProtKB - P32867 (SSO1_YEAST)

Entry version 171 (07 Oct 2020)
Sequence version 2 (01 Feb 1995)
Previous versions | rss
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Protein

Protein SSO1

Gene

SSO1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for vesicle fusion with the plasma membrane.

Miscellaneous

Present with 450 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-SCE-114516, Disinhibition of SNARE formation
R-SCE-199992, trans-Golgi Network Vesicle Budding
R-SCE-9609523, Insertion of tail-anchored proteins into the endoplasmic reticulum membrane

Protein family/group databases

Transport Classification Database

More...TCDBi		8.A.91.1.5, the syntaxin (syntaxin) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein SSO1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SSO1
Ordered Locus Names:YPL232W
ORF Names:P1405
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XVI

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		FungiDB:YPL232W

Saccharomyces Genome Database

More...SGDi		S000006153, SSO1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 265CytoplasmicSequence analysisAdd BLAST265
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei266 – 287Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST22
Topological domaini288 – 290ExtracellularSequence analysis3

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002102741 – 290Protein SSO1Add BLAST290

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		P32867

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P32867

PRoteomics IDEntifications database

More...PRIDEi		P32867

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P32867

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P32867

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		35930, 139 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-1365, Vesicular SNARE complex SSO1-SEC9-SNC1
CPX-5463, Vesicular SNARE complex SSO1-SEC9-SNC2
CPX-5464, Vesicular SNARE complex SSO1-SPO20-SNC1
CPX-5466, Vesicular SNARE complex SSO1-SPO20-SNC2
CPX-5521, Vacuolar SNARE complex SSO1-SEC9-NYV1

Database of interacting proteins

More...DIPi		DIP-2494N

Protein interaction database and analysis system

More...IntActi		P32867, 7 interactors

STRING: functional protein association networks

More...STRINGi		4932.YPL232W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P32867, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1290
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Biological Magnetic Resonance Data Bank

More...BMRBi		P32867

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P32867

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P32867

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini190 – 252t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST63

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the syntaxin family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0810, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT01000000214380

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_042423_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P32867

KEGG Orthology (KO)

More...KOi		K08486

Identification of Orthologs from Complete Genome Data

More...OMAi		RNRKKWW

Family and domain databases

Conserved Domains Database

More...CDDi		cd00179, SynN, 1 hit

Database of protein disorder

More...DisProti		DP01503

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR010989, SNARE
IPR006012, Syntaxin/epimorphin_CS
IPR006011, Syntaxin_N
IPR000727, T_SNARE_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF05739, SNARE, 1 hit
PF00804, Syntaxin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00503, SynN, 1 hit
SM00397, t_SNARE, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47661, SSF47661, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00914, SYNTAXIN, 1 hit
PS50192, T_SNARE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P32867-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSYNNPYQLE TPFEESYELD EGSSAIGAEG HDFVGFMNKI SQINRDLDKY 
        60         70         80         90        100
DHTINQVDSL HKRLLTEVNE EQASHLRHSL DNFVAQATDL QFKLKNEIKS 
       110        120        130        140        150
AQRDGIHDTN KQAQAENSRQ RFLKLIQDYR IVDSNYKEEN KEQAKRQYMI 
       160        170        180        190        200
IQPEATEDEV EAAISDVGGQ QIFSQALLNA NRRGEAKTAL AEVQARHQEL 
       210        220        230        240        250
LKLEKSMAEL TQLFNDMEEL VIEQQENVDV IDKNVEDAQL DVEQGVGHTD 
       260        270        280        290
KAVKSARKAR KNKIRCWLIV FAIIVVVVVV VVVPAVVKTR
Length:290
Mass (Da):33,106
Last modified:February 1, 1995 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6E4C6D35C3CD9D94
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti97E → G no nucleotide entry (PubMed:2900835).Curated1
Sequence conflicti105G → V no nucleotide entry (PubMed:2900835).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X67729 mRNA Translation: CAA47959.1
X76890 Genomic DNA Translation: CAA54217.1
X94561 Genomic DNA Translation: CAA64255.1
Z73588 Genomic DNA Translation: CAA97949.1
J03936 Genomic DNA No translation available.
BK006949 Genomic DNA Translation: DAA11204.1

Protein sequence database of the Protein Information Resource

More...PIRi		S39569

NCBI Reference Sequences

More...RefSeqi		NP_015092.1, NM_001184046.1

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		YPL232W_mRNA; YPL232W; YPL232W

Database of genes from NCBI RefSeq genomes

More...GeneIDi		855844

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		sce:YPL232W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67729 mRNA Translation: CAA47959.1
X76890 Genomic DNA Translation: CAA54217.1
X94561 Genomic DNA Translation: CAA64255.1
Z73588 Genomic DNA Translation: CAA97949.1
J03936 Genomic DNA No translation available.
BK006949 Genomic DNA Translation: DAA11204.1
PIRiS39569
RefSeqiNP_015092.1, NM_001184046.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FIOX-ray2.10A31-225[»]
3B5NX-ray1.60B/F/J189-257[»]
BMRBiP32867
SMRiP32867
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi35930, 139 interactors
ComplexPortaliCPX-1365, Vesicular SNARE complex SSO1-SEC9-SNC1
CPX-5463, Vesicular SNARE complex SSO1-SEC9-SNC2
CPX-5464, Vesicular SNARE complex SSO1-SPO20-SNC1
CPX-5466, Vesicular SNARE complex SSO1-SPO20-SNC2
CPX-5521, Vacuolar SNARE complex SSO1-SEC9-NYV1
DIPiDIP-2494N
IntActiP32867, 7 interactors
STRINGi4932.YPL232W

Protein family/group databases

TCDBi8.A.91.1.5, the syntaxin (syntaxin) family

PTM databases

iPTMnetiP32867
SwissPalmiP32867

Proteomic databases

MaxQBiP32867
PaxDbiP32867
PRIDEiP32867

Genome annotation databases

EnsemblFungiiYPL232W_mRNA; YPL232W; YPL232W
GeneIDi855844
KEGGisce:YPL232W

Organism-specific databases

EuPathDBiFungiDB:YPL232W
SGDiS000006153, SSO1

Phylogenomic databases

eggNOGiKOG0810, Eukaryota
GeneTreeiENSGT01000000214380
HOGENOMiCLU_042423_0_1_1
InParanoidiP32867
KOiK08486
OMAiRNRKKWW

Enzyme and pathway databases

ReactomeiR-SCE-114516, Disinhibition of SNARE formation
R-SCE-199992, trans-Golgi Network Vesicle Budding
R-SCE-9609523, Insertion of tail-anchored proteins into the endoplasmic reticulum membrane

Miscellaneous databases

EvolutionaryTraceiP32867

Protein Ontology

More...PROi		PR:P32867
RNActiP32867, protein

Family and domain databases

CDDicd00179, SynN, 1 hit
DisProtiDP01503
InterProiView protein in InterPro
IPR010989, SNARE
IPR006012, Syntaxin/epimorphin_CS
IPR006011, Syntaxin_N
IPR000727, T_SNARE_dom
PfamiView protein in Pfam
PF05739, SNARE, 1 hit
PF00804, Syntaxin, 1 hit
SMARTiView protein in SMART
SM00503, SynN, 1 hit
SM00397, t_SNARE, 1 hit
SUPFAMiSSF47661, SSF47661, 1 hit
PROSITEiView protein in PROSITE
PS00914, SYNTAXIN, 1 hit
PS50192, T_SNARE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSSO1_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P32867
Secondary accession number(s): D6W3D8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: February 1, 1995
Last modified: October 7, 2020
This is version 171 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names
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