UniProtKB - P32867 (SSO1_YEAST)
Protein
Protein SSO1
Gene
SSO1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Required for vesicle fusion with the plasma membrane.
Miscellaneous
Present with 450 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- phosphatidic acid binding Source: SGD
- phosphatidylinositol-3,4-bisphosphate binding Source: SGD
- phosphatidylinositol-3,5-bisphosphate binding Source: SGD
- phosphatidylinositol-4,5-bisphosphate binding Source: SGD
- SNAP receptor activity Source: SGD
- SNARE binding Source: CAFA
GO - Biological processi
- ascospore formation Source: SGD
- ascospore-type prospore assembly Source: SGD
- exocytosis Source: GO_Central
- intracellular protein transport Source: GO_Central
- SNARE complex assembly Source: CAFA
- vesicle docking Source: GO_Central
- vesicle fusion Source: SGD
Enzyme and pathway databases
Reactomei | R-SCE-114516, Disinhibition of SNARE formation R-SCE-199992, trans-Golgi Network Vesicle Budding R-SCE-204005, COPII-mediated vesicle transport |
Protein family/group databases
TCDBi | 8.A.91.1.5, the syntaxin (syntaxin) family |
Names & Taxonomyi
Protein namesi | Recommended name: Protein SSO1 |
Gene namesi | Name:SSO1 Ordered Locus Names:YPL232W ORF Names:P1405 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000006153, SSO1 |
VEuPathDBi | FungiDB:YPL232W |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass type IV membrane protein Curated
Plasma Membrane
- plasma membrane Source: SGD
Vacuole
- fungal-type vacuole membrane Source: SGD
Other locations
- cell periphery Source: SGD
- endomembrane system Source: GO_Central
- integral component of membrane Source: GO_Central
- prospore membrane Source: SGD
- SNARE complex Source: SGD
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 265 | CytoplasmicSequence analysisAdd BLAST | 265 | |
Transmembranei | 266 – 287 | Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST | 22 | |
Topological domaini | 288 – 290 | ExtracellularSequence analysis | 3 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000210274 | 1 – 290 | Protein SSO1Add BLAST | 290 |
Proteomic databases
MaxQBi | P32867 |
PaxDbi | P32867 |
PRIDEi | P32867 |
PTM databases
iPTMneti | P32867 |
SwissPalmi | P32867 |
Interactioni
Binary interactionsi
Hide detailsP32867
With | #Exp. | IntAct |
---|---|---|
SEC22 [P22214] | 2 | EBI-2206525,EBI-16577 |
SEC9 [P40357] | 14 | EBI-2206525,EBI-16904 |
SNC2 [P33328] | 2 | EBI-2206525,EBI-17512 |
GO - Molecular functioni
- SNARE binding Source: CAFA
Protein-protein interaction databases
BioGRIDi | 35930, 139 interactors |
ComplexPortali | CPX-1365, Vesicular SNARE complex SSO1-SEC9-SNC1 CPX-5463, Vesicular SNARE complex SSO1-SEC9-SNC2 CPX-5464, Vesicular SNARE complex SSO1-SPO20-SNC1 CPX-5466, Vesicular SNARE complex SSO1-SPO20-SNC2 CPX-5521, Vacuolar SNARE complex SSO1-SEC9-NYV1 |
DIPi | DIP-2494N |
IntActi | P32867, 7 interactors |
STRINGi | 4932.YPL232W |
Miscellaneous databases
RNActi | P32867, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
BMRBi | P32867 |
SMRi | P32867 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P32867 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 190 – 252 | t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST | 63 |
Sequence similaritiesi
Belongs to the syntaxin family.Curated
Keywords - Domaini
Coiled coil, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0810, Eukaryota |
GeneTreei | ENSGT01000000214440 |
HOGENOMi | CLU_042423_0_1_1 |
InParanoidi | P32867 |
OMAi | RNRKKWW |
Family and domain databases
CDDi | cd00179, SynN, 1 hit |
DisProti | DP01503 |
InterProi | View protein in InterPro IPR010989, SNARE IPR006012, Syntaxin/epimorphin_CS IPR006011, Syntaxin_N IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit PF00804, Syntaxin, 1 hit |
SMARTi | View protein in SMART SM00503, SynN, 1 hit SM00397, t_SNARE, 1 hit |
SUPFAMi | SSF47661, SSF47661, 1 hit |
PROSITEi | View protein in PROSITE PS00914, SYNTAXIN, 1 hit PS50192, T_SNARE, 1 hit |
i Sequence
Sequence statusi: Complete.
P32867-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSYNNPYQLE TPFEESYELD EGSSAIGAEG HDFVGFMNKI SQINRDLDKY
60 70 80 90 100
DHTINQVDSL HKRLLTEVNE EQASHLRHSL DNFVAQATDL QFKLKNEIKS
110 120 130 140 150
AQRDGIHDTN KQAQAENSRQ RFLKLIQDYR IVDSNYKEEN KEQAKRQYMI
160 170 180 190 200
IQPEATEDEV EAAISDVGGQ QIFSQALLNA NRRGEAKTAL AEVQARHQEL
210 220 230 240 250
LKLEKSMAEL TQLFNDMEEL VIEQQENVDV IDKNVEDAQL DVEQGVGHTD
260 270 280 290
KAVKSARKAR KNKIRCWLIV FAIIVVVVVV VVVPAVVKTR
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 97 | E → G no nucleotide entry (PubMed:2900835).Curated | 1 | |
Sequence conflicti | 105 | G → V no nucleotide entry (PubMed:2900835).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X67729 mRNA Translation: CAA47959.1 X76890 Genomic DNA Translation: CAA54217.1 X94561 Genomic DNA Translation: CAA64255.1 Z73588 Genomic DNA Translation: CAA97949.1 J03936 Genomic DNA No translation available. BK006949 Genomic DNA Translation: DAA11204.1 |
PIRi | S39569 |
RefSeqi | NP_015092.1, NM_001184046.1 |
Genome annotation databases
EnsemblFungii | YPL232W_mRNA; YPL232W; YPL232W |
GeneIDi | 855844 |
KEGGi | sce:YPL232W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X67729 mRNA Translation: CAA47959.1 X76890 Genomic DNA Translation: CAA54217.1 X94561 Genomic DNA Translation: CAA64255.1 Z73588 Genomic DNA Translation: CAA97949.1 J03936 Genomic DNA No translation available. BK006949 Genomic DNA Translation: DAA11204.1 |
PIRi | S39569 |
RefSeqi | NP_015092.1, NM_001184046.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1FIO | X-ray | 2.10 | A | 31-225 | [»] | |
3B5N | X-ray | 1.60 | B/F/J | 189-257 | [»] | |
BMRBi | P32867 | |||||
SMRi | P32867 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 35930, 139 interactors |
ComplexPortali | CPX-1365, Vesicular SNARE complex SSO1-SEC9-SNC1 CPX-5463, Vesicular SNARE complex SSO1-SEC9-SNC2 CPX-5464, Vesicular SNARE complex SSO1-SPO20-SNC1 CPX-5466, Vesicular SNARE complex SSO1-SPO20-SNC2 CPX-5521, Vacuolar SNARE complex SSO1-SEC9-NYV1 |
DIPi | DIP-2494N |
IntActi | P32867, 7 interactors |
STRINGi | 4932.YPL232W |
Protein family/group databases
TCDBi | 8.A.91.1.5, the syntaxin (syntaxin) family |
PTM databases
iPTMneti | P32867 |
SwissPalmi | P32867 |
Proteomic databases
MaxQBi | P32867 |
PaxDbi | P32867 |
PRIDEi | P32867 |
Genome annotation databases
EnsemblFungii | YPL232W_mRNA; YPL232W; YPL232W |
GeneIDi | 855844 |
KEGGi | sce:YPL232W |
Organism-specific databases
SGDi | S000006153, SSO1 |
VEuPathDBi | FungiDB:YPL232W |
Phylogenomic databases
eggNOGi | KOG0810, Eukaryota |
GeneTreei | ENSGT01000000214440 |
HOGENOMi | CLU_042423_0_1_1 |
InParanoidi | P32867 |
OMAi | RNRKKWW |
Enzyme and pathway databases
Reactomei | R-SCE-114516, Disinhibition of SNARE formation R-SCE-199992, trans-Golgi Network Vesicle Budding R-SCE-204005, COPII-mediated vesicle transport |
Miscellaneous databases
EvolutionaryTracei | P32867 |
PROi | PR:P32867 |
RNActi | P32867, protein |
Family and domain databases
CDDi | cd00179, SynN, 1 hit |
DisProti | DP01503 |
InterProi | View protein in InterPro IPR010989, SNARE IPR006012, Syntaxin/epimorphin_CS IPR006011, Syntaxin_N IPR000727, T_SNARE_dom |
Pfami | View protein in Pfam PF05739, SNARE, 1 hit PF00804, Syntaxin, 1 hit |
SMARTi | View protein in SMART SM00503, SynN, 1 hit SM00397, t_SNARE, 1 hit |
SUPFAMi | SSF47661, SSF47661, 1 hit |
PROSITEi | View protein in PROSITE PS00914, SYNTAXIN, 1 hit PS50192, T_SNARE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SSO1_YEAST | |
Accessioni | P32867Primary (citable) accession number: P32867 Secondary accession number(s): D6W3D8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1993 |
Last sequence update: | February 1, 1995 | |
Last modified: | April 7, 2021 | |
This is version 174 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XVI
Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families