Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Transcription termination/antitermination protein NusA

Gene

nusA

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Participates in both transcription termination and antitermination.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-binding
Biological processTranscription, Transcription antitermination, Transcription regulation, Transcription termination

Enzyme and pathway databases

BioCyciBSUB:BSU16600-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription termination/antitermination protein NusAUniRule annotation
Gene namesi
Name:nusAUniRule annotation
Ordered Locus Names:BSU16600
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001819601 – 371Transcription termination/antitermination protein NusAAdd BLAST371

Proteomic databases

PaxDbiP32727
PRIDEiP32727

Interactioni

Subunit structurei

Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.UniRule annotation

Protein-protein interaction databases

IntActiP32727, 1 interactor
MINTiP32727
STRINGi224308.Bsubs1_010100009146

Structurei

Secondary structure

1371
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 13Combined sources10
Helixi20 – 36Combined sources17
Turni40 – 42Combined sources3
Beta strandi46 – 50Combined sources5
Turni51 – 54Combined sources4
Beta strandi55 – 67Combined sources13
Helixi77 – 81Combined sources5
Beta strandi92 – 96Combined sources5
Helixi102 – 123Combined sources22

3D structure databases

ProteinModelPortaliP32727
SMRiP32727
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini135 – 199S1 motifUniRule annotationAdd BLAST65
Domaini301 – 367KHUniRule annotationAdd BLAST67

Sequence similaritiesi

Belongs to the NusA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CHV Bacteria
COG0195 LUCA
HOGENOMiHOG000006395
InParanoidiP32727
KOiK02600
OMAiSRTTPKM
PhylomeDBiP32727

Family and domain databases

Gene3Di3.30.1480.10, 1 hit
3.30.300.20, 2 hits
HAMAPiMF_00945_B NusA_B, 1 hit
InterProiView protein in InterPro
IPR004087 KH_dom
IPR015946 KH_dom-like_a/b
IPR025249 KH_dom_NusA-like
IPR009019 KH_sf_prok-type
IPR012340 NA-bd_OB-fold
IPR030842 NusA_bac
IPR036555 NusA_N_sf
IPR022967 S1_dom
IPR003029 S1_domain
IPR013735 TF_NusA_N
IPR010213 Tscrpt_termination_fac_NusA
PANTHERiPTHR22648 PTHR22648, 1 hit
PfamiView protein in Pfam
PF13184 KH_5, 1 hit
PF08529 NusA_N, 1 hit
PF00575 S1, 1 hit
SMARTiView protein in SMART
SM00322 KH, 2 hits
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54814 SSF54814, 2 hits
SSF69705 SSF69705, 1 hit
TIGRFAMsiTIGR01953 NusA, 1 hit
PROSITEiView protein in PROSITE
PS50084 KH_TYPE_1, 1 hit
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

P32727-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSELLDALT ILEKEKGISK EIIIEAIEAA LISAYKRNFN QAQNVRVDLN
60 70 80 90 100
RETGSIRVFA RKDVVDEVYD QRLEISIEEA QGIHPEYMVG DVVEIEVTPK
110 120 130 140 150
DFGRIAAQTA KQVVTQRVRE AERGVIYSEF IDREEDIMTG IVQRLDNKFI
160 170 180 190 200
YVSLGKIEAL LPVNEQMPNE SYKPHDRIKV YITKVEKTTK GPQIYVSRTH
210 220 230 240 250
PGLLKRLFEI EVPEIYDGTV ELKSVAREAG DRSKISVRTD DPDVDPVGSC
260 270 280 290 300
VGPKGQRVQA IVNELKGEKI DIVNWSSDPV EFVANALSPS KVLDVIVNEE
310 320 330 340 350
EKATTVIVPD YQLSLAIGKR GQNARLAAKL TGWKIDIKSE TDARELGIYP
360 370
RELEEDDEPL FTEPETAESD E
Length:371
Mass (Da):41,725
Last modified:May 30, 2000 - v2
Checksum:i2FC7861E4C3094D3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti111 – 112KQ → NE in CAA79231 (PubMed:8491709).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z18631 Genomic DNA Translation: CAA79231.1
AL009126 Genomic DNA Translation: CAB13533.1
PIRiC36905
RefSeqiNP_389542.1, NC_000964.3
WP_003231912.1, NZ_JNCM01000035.1

Genome annotation databases

EnsemblBacteriaiCAB13533; CAB13533; BSU16600
GeneIDi939628
KEGGibsu:BSU16600
PATRICifig|224308.179.peg.1801

Similar proteinsi

Entry informationi

Entry nameiNUSA_BACSU
AccessioniPrimary (citable) accession number: P32727
Secondary accession number(s): O31756
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: May 30, 2000
Last modified: July 18, 2018
This is version 138 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health