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Entry version 162 (25 May 2022)
Sequence version 1 (01 Oct 1993)
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Protein

Uncharacterized protein YEL043W

Gene

YEL043W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Present with 149 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein YEL043W
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:YEL043W
ORF Names:SYGP-ORF14
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome V

Organism-specific databases

Saccharomyces Genome Database

More...
SGDi
S000000769, YEL043W

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:YEL043W

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002026071 – 956Uncharacterized protein YEL043WAdd BLAST956

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei154PhosphothreonineCombined sources1
Modified residuei501PhosphoserineCombined sources1
Modified residuei520PhosphoserineCombined sources1
Modified residuei802PhosphoserineCombined sources1
Modified residuei842PhosphoserineCombined sources1
Modified residuei895PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P32618

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P32618

PRoteomics IDEntifications database

More...
PRIDEi
P32618

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P32618

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
36686, 226 interactors

Database of interacting proteins

More...
DIPi
DIP-2682N

Protein interaction database and analysis system

More...
IntActi
P32618, 8 interactors

Molecular INTeraction database

More...
MINTi
P32618

STRING: functional protein association networks

More...
STRINGi
4932.YEL043W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P32618, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...
AlphaFoldDBi
P32618

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P32618

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini40 – 141Fibronectin type-IIIPROSITE-ProRule annotationAdd BLAST102

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni152 – 173DisorderedSequence analysisAdd BLAST22
Regioni488 – 600DisorderedSequence analysisAdd BLAST113
Regioni875 – 956DisorderedSequence analysisAdd BLAST82

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi488 – 544Polar residuesSequence analysisAdd BLAST57
Compositional biasi551 – 600Polar residuesSequence analysisAdd BLAST50
Compositional biasi890 – 956Polar residuesSequence analysisAdd BLAST67

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R2RI, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012632_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P32618

Identification of Orthologs from Complete Genome Data

More...
OMAi
NYSKGFT

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063, FN3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265, SSF49265, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853, FN3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P32618-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPVSVITTVL ACLWLSYRLY KFLTIPVSSI VSTLKIKTPP ATKVSIDKIA
60 70 80 90 100
TDSVTIHWEN EPVKAEDNGS ADRNFISHYL LYLNNTQLAI FPNNPNSLYT
110 120 130 140 150
CCSITGLEAE TQYQLDFITI NNKGFINKLP SIYCMTKARE ANEALKTRKW
160 170 180 190 200
RRNTITSSTA MQPRNSKSEP APLPSHYSSV SLSTFSSNIT NSATSNNGSN
210 220 230 240 250
LPAYTSLTTL KDLDSFSIDD LKKILICAQE DLHDVLSQQT SLLQDFQESK
260 270 280 290 300
LELELELDNL KTHWSHEIDL RKSLKSNIKS LENSKLLTDL KIEKLNKKID
310 320 330 340 350
KSKEKISKMR NDMQKWSQED TELLSKDTIK EKYFKLLNES NASVANINKE
360 370 380 390 400
IESLQNEISK MEESNKRLNA SKKSLITSIV VNANVENDKP IASGELSAVL
410 420 430 440 450
KKLNDFTLEK NGFLSNAGEE FLSKLNADSS LIKMIKQELS IDQELEANWK
460 470 480 490 500
LQRSNLLKKI SALENQFNEM SLNNRNLKTK LMVQPYKNNG DSLAATNSNN
510 520 530 540 550
SAEKNRSSGS IQLPLSNNMS RTGSIDLISN NNKSINNSNA DSAPPLRLHN
560 570 580 590 600
PVSYSPSNEP IQPSSSLLSQ LTQDTDNRSM LSNHISSNNE NKQQPSSYSH
610 620 630 640 650
ALPTTATANA TATATATNGH SRSNLWTTAQ FAQPSHQQVS TELDQAFEYD
660 670 680 690 700
NANHLISGLQ NMIYDETDYP DNISNYSKGF TTDELDNYWT KQQPQVRSTN
710 720 730 740 750
ESLFSTTGTP MSSYKANPVI SPYSSSHLRQ TSNATNTNPM HPQSLLAATL
760 770 780 790 800
NDPSLQSFVR SGSFYSAPQP ANSLQNNING NETENISPRI SSDFNLLVPN
810 820 830 840 850
LSPRLSNDVP IVPGNNTTLT PSHSNILTMN HQPTADNITR RSFHASSPPF
860 870 880 890 900
NSIWNSNTNQ LSPPLEEQYH LDVPVGPKVP AKEPSPKPSH KRNQSNSSIS
910 920 930 940 950
SAWSKFKHKS ASSPANADTD IQDSSTPSTS PSGRRMSKLL SKSGMNNLFN

PHSHDS
Length:956
Mass (Da):106,133
Last modified:October 1, 1993 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3F78B09A0FCA03AF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti467F → S in AAU09716 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U18779 Genomic DNA Translation: AAB64999.1
AY723799 Genomic DNA Translation: AAU09716.1
BK006939 Genomic DNA Translation: DAA07610.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S30834

NCBI Reference Sequences

More...
RefSeqi
NP_010871.3, NM_001178858.3

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YEL043W_mRNA; YEL043W; YEL043W

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
856668

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YEL043W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18779 Genomic DNA Translation: AAB64999.1
AY723799 Genomic DNA Translation: AAU09716.1
BK006939 Genomic DNA Translation: DAA07610.1
PIRiS30834
RefSeqiNP_010871.3, NM_001178858.3

3D structure databases

AlphaFoldDBiP32618
SMRiP32618
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi36686, 226 interactors
DIPiDIP-2682N
IntActiP32618, 8 interactors
MINTiP32618
STRINGi4932.YEL043W

PTM databases

iPTMnetiP32618

Proteomic databases

MaxQBiP32618
PaxDbiP32618
PRIDEiP32618

Genome annotation databases

EnsemblFungiiYEL043W_mRNA; YEL043W; YEL043W
GeneIDi856668
KEGGisce:YEL043W

Organism-specific databases

SGDiS000000769, YEL043W
VEuPathDBiFungiDB:YEL043W

Phylogenomic databases

eggNOGiENOG502R2RI, Eukaryota
HOGENOMiCLU_012632_0_0_1
InParanoidiP32618
OMAiNYSKGFT

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P32618
RNActiP32618, protein

Family and domain databases

CDDicd00063, FN3, 1 hit
Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold
SUPFAMiSSF49265, SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50853, FN3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYEF3_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P32618
Secondary accession number(s): D3DLK6, Q66RC2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: May 25, 2022
This is version 162 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names
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