UniProtKB - P32522 (PT309_YEAST)
Protein
Pentatricopeptide repeat-containing protein PET309, mitochondrial
Gene
PET309
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Required for initiation of translation of the COX1 coding region. Also involved in the stability of the intron containing transcript of COX1.
Miscellaneous
Present with 1160 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- mRNA binding Source: SGD
- translation regulator activity Source: SGD
- tRNA binding Source: UniProtKB
GO - Biological processi
- mitochondrial cytochrome c oxidase assembly Source: SGD
- positive regulation of mitochondrial translational initiation Source: SGD
- tRNA 3'-end processing Source: UniProtKB
Names & Taxonomyi
Protein namesi | Recommended name: Pentatricopeptide repeat-containing protein PET309, mitochondrial |
Gene namesi | Name:PET309 Ordered Locus Names:YLR067C ORF Names:L2189 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000004057, PET309 |
VEuPathDBi | FungiDB:YLR067C |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane Curated; Single-pass membrane protein Curated
Mitochondrion
- extrinsic component of mitochondrial inner membrane Source: SGD
- mitochondrial matrix Source: UniProtKB
- mitochondrion Source: SGD
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 237 – 256 | HelicalSequence analysisAdd BLAST | 20 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – ? | MitochondrionSequence analysis | ||
ChainiPRO_0000022179 | ? – 965 | Pentatricopeptide repeat-containing protein PET309, mitochondrial |
Proteomic databases
MaxQBi | P32522 |
PaxDbi | P32522 |
PRIDEi | P32522 |
PTM databases
iPTMneti | P32522 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 31341, 109 interactors |
DIPi | DIP-932N |
IntActi | P32522, 4 interactors |
MINTi | P32522 |
STRINGi | 4932.YLR067C |
Miscellaneous databases
RNActi | P32522, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 310 – 344 | PPR 1Add BLAST | 35 | |
Repeati | 345 – 379 | PPR 2Add BLAST | 35 | |
Repeati | 380 – 414 | PPR 3Add BLAST | 35 | |
Repeati | 415 – 450 | PPR 4Add BLAST | 36 | |
Repeati | 451 – 486 | PPR 5Add BLAST | 36 | |
Repeati | 487 – 523 | PPR 6Add BLAST | 37 | |
Repeati | 524 – 558 | PPR 7Add BLAST | 35 | |
Repeati | 559 – 595 | PPR 8Add BLAST | 37 | |
Repeati | 596 – 630 | PPR 9Add BLAST | 35 | |
Repeati | 680 – 714 | PPR 10Add BLAST | 35 | |
Repeati | 723 – 763 | PPR 11Add BLAST | 41 | |
Repeati | 774 – 808 | PPR 12Add BLAST | 35 | |
Repeati | 809 – 844 | PPR 13Add BLAST | 36 |
Keywords - Domaini
Repeat, Transit peptide, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG4197, Eukaryota |
GeneTreei | ENSGT00390000016775 |
HOGENOMi | CLU_306786_0_0_1 |
InParanoidi | P32522 |
OMAi | HGYNLIH |
Family and domain databases
Gene3Di | 1.25.40.10, 2 hits |
InterProi | View protein in InterPro IPR002885, Pentatricopeptide_repeat IPR011990, TPR-like_helical_dom_sf |
PROSITEi | View protein in PROSITE PS51375, PPR, 9 hits |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P32522-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKRCAPAVLR NYNYKKGIWS TGVPDHIRKL LRDKSTSPLC SQDERNLVSY
60 70 80 90 100
FMARGSVPLK SVGSGLTKKA TTSITSNSAT TTFERQYLIK YLYRHQAYGN
110 120 130 140 150
VIKIAQKFLY TTIGSQRLLK QDASLPELKK FLLSLLILQR GIQLDQAISD
160 170 180 190 200
IIQRFLLTQK TMVIDLINSI FSRMVIMNMH EEAVYKWVKW MKLVNGHCEF
210 220 230 240 250
TNYMENKIVL RNFLSFMRQS NVRPDYLSYL KAIQLTQGPA IASQFATTLL
260 270 280 290 300
FLLTYIRKFS SAEAVWNYKC EHNLPIVSSD LTCILKTYCH MQKFNLVSST
310 320 330 340 350
YWKYPDAQHD QNQFDYLLVA HSRLHNWDAL QQQFNALFGI GKLPSIQHYG
360 370 380 390 400
ILMYTMARIG ELDSVNKLYT QLLRRGMIPT YAVLQSLLYA HYKVGDFAAC
410 420 430 440 450
FSHFELFKKY DITPSTATHT IMLKVYRGLN DLDGAFRILK RLSEDPSVEI
460 470 480 490 500
TEGHFALLIQ MCCKTTNHLI AQELFNLMTE HYNIQHTGKS ISALMDVYIE
510 520 530 540 550
SNRPTEAIAL FEKHSKNLSW RDGLISVYNK AIKAYIGLRN ANKCEELFDK
560 570 580 590 600
ITTSKLAVNS EFYKMMIKFL VTLNEDCETA LSIIDQLIKH SVIKVDATHF
610 620 630 640 650
EIIMEAYDKE GYRDGIINLY KTMSQNKVPA NSKILYYILK AVAKKSLQNN
660 670 680 690 700
EEIKETINMV EDIMENAANG TLDVTYNKLH PSVMAWPMRM IVKHDSPQRA
710 720 730 740 750
LELYNRYNEL FFKKHDWISN NNKFVMMRSL LVLLAQIEQW KDFETLFAKY
760 770 780 790 800
MDRIENIENL PSSTTPNIKL RSIFSGLFPY KVSQLIAMNK IDELPLLWKK
810 820 830 840 850
LREKGFILDN ISWNSAVEAL FKDPRTLSYG MKIVDDTLIH GYNLIHKFRL
860 870 880 890 900
LTKLSEDKTQ SSDKSWPTLK MKEKEPNKFQ PRLYLKSDTY NSIMRQLDTY
910 920 930 940 950
LDGIDDLKTL EDQVRDFISN YKYFMKDYLL MPRSKINKWE QIEMRHLSYF
960
KELRKSKRVL PVSKF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L06072 Genomic DNA Translation: AAA34856.1 X94607 Genomic DNA Translation: CAA64313.1 Z73239 Genomic DNA Translation: CAA97623.1 Z73240 Genomic DNA Translation: CAA97625.1 BK006945 Genomic DNA Translation: DAA09384.1 |
PIRi | S58393 |
RefSeqi | NP_013168.1, NM_001181954.1 |
Genome annotation databases
EnsemblFungii | YLR067C_mRNA; YLR067C; YLR067C |
GeneIDi | 850756 |
KEGGi | sce:YLR067C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L06072 Genomic DNA Translation: AAA34856.1 X94607 Genomic DNA Translation: CAA64313.1 Z73239 Genomic DNA Translation: CAA97623.1 Z73240 Genomic DNA Translation: CAA97625.1 BK006945 Genomic DNA Translation: DAA09384.1 |
PIRi | S58393 |
RefSeqi | NP_013168.1, NM_001181954.1 |
3D structure databases
SMRi | P32522 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 31341, 109 interactors |
DIPi | DIP-932N |
IntActi | P32522, 4 interactors |
MINTi | P32522 |
STRINGi | 4932.YLR067C |
PTM databases
iPTMneti | P32522 |
Proteomic databases
MaxQBi | P32522 |
PaxDbi | P32522 |
PRIDEi | P32522 |
Genome annotation databases
EnsemblFungii | YLR067C_mRNA; YLR067C; YLR067C |
GeneIDi | 850756 |
KEGGi | sce:YLR067C |
Organism-specific databases
SGDi | S000004057, PET309 |
VEuPathDBi | FungiDB:YLR067C |
Phylogenomic databases
eggNOGi | KOG4197, Eukaryota |
GeneTreei | ENSGT00390000016775 |
HOGENOMi | CLU_306786_0_0_1 |
InParanoidi | P32522 |
OMAi | HGYNLIH |
Miscellaneous databases
ChiTaRSi | PET309, yeast |
PROi | PR:P32522 |
RNActi | P32522, protein |
Family and domain databases
Gene3Di | 1.25.40.10, 2 hits |
InterProi | View protein in InterPro IPR002885, Pentatricopeptide_repeat IPR011990, TPR-like_helical_dom_sf |
PROSITEi | View protein in PROSITE PS51375, PPR, 9 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PT309_YEAST | |
Accessioni | P32522Primary (citable) accession number: P32522 Secondary accession number(s): D6VY68 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1993 |
Last sequence update: | October 1, 1993 | |
Last modified: | February 10, 2021 | |
This is version 156 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XII
Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names