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UniProtKB - P32320 (CDD_HUMAN)

Entry version 185 (07 Apr 2021)
Sequence version 2 (01 Oct 1996)
Previous versions | rss
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Protein

Cytidine deaminase

Gene

CDA

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi65Zinc; catalytic1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei67Proton donor1
Metal bindingi99Zinc; catalytic1
Metal bindingi102Zinc; catalytic1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		MetaCyc:HS08334-MONOMER

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		3.5.4.5, 2681

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P32320

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-6798695, Neutrophil degranulation
R-HSA-73614, Pyrimidine salvage

SABIO-RK: Biochemical Reaction Kinetics Database

More...SABIO-RKi		P32320

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cytidine deaminase (EC:3.5.4.5)
Alternative name(s):
Cytidine aminohydrolase
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDA
Synonyms:CDD
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:1712, CDA

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		123920, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P32320

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000158825.5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		978

Open Targets

More...OpenTargetsi		ENSG00000158825

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA98

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P32320, Tchem

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL4502

Drug and drug target database

More...DrugBanki		DB03185, 1-Beta-Ribofuranosyl-1,3-Diazepinone
DB00928, Azacitidine
DB01101, Capecitabine
DB15694, Cedazuridine
DB00987, Cytarabine
DB01262, Decitabine
DB00441, Gemcitabine

IUPHAR/BPS Guide to PHARMACOLOGY

More...GuidetoPHARMACOLOGYi		3133

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CDA

Domain mapping of disease mutations (DMDM)

More...DMDMi		1705718

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001716821 – 146Cytidine deaminaseAdd BLAST146

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P32320

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P32320

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P32320

MaxQB - The MaxQuant DataBase

More...MaxQBi		P32320

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P32320

PeptideAtlas

More...PeptideAtlasi		P32320

PRoteomics IDEntifications database

More...PRIDEi		P32320

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		54869

Consortium for Top Down Proteomics

More...TopDownProteomicsi		P32320

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P32320

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P32320

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000158825, Expressed in blood and 138 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P32320, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000158825, Tissue enhanced (blood, bone marrow)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homotetramer.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		107416, 47 interactors

Protein interaction database and analysis system

More...IntActi		P32320, 26 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000364212

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		P32320

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P32320, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1146
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P32320

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P32320

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini13 – 140CMP/dCMP-type deaminasePROSITE-ProRule annotationAdd BLAST128

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni54 – 60Substrate binding7

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the cytidine and deoxycytidylate deaminase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0833, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000000911

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_097262_1_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P32320

Identification of Orthologs from Complete Genome Data

More...OMAi		LTHFTCV

Database of Orthologous Groups

More...OrthoDBi		1400471at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P32320

TreeFam database of animal gene trees

More...TreeFami		TF314486

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016192, APOBEC/CMP_deaminase_Zn-bd
IPR002125, CMP_dCMP_dom
IPR006262, Cyt_deam_tetra
IPR016193, Cytidine_deaminase-like

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00383, dCMP_cyt_deam_1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53927, SSF53927, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01354, cyt_deam_tetra, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00903, CYT_DCMP_DEAMINASES_1, 1 hit
PS51747, CYT_DCMP_DEAMINASES_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P32320-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQKRPACTL KPECVQQLLV CSQEAKKSAY CPYSHFPVGA ALLTQEGRIF 
        60         70         80         90        100
KGCNIENACY PLGICAERTA IQKAVSEGYK DFRAIAIASD MQDDFISPCG 
       110        120        130        140 
ACRQVMREFG TNWPVYMTKP DGTYIVMTVQ ELLPSSFGPE DLQKTQ
Length:146
Mass (Da):16,185
Last modified:October 1, 1996 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAF33D09EE4E176B3
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02155927K → Q2 PublicationsCorresponds to variant dbSNP:rs2072671Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
L27943 mRNA Translation: AAA57254.1
AF061658 AF061657 Genomic DNA Translation: AAD15828.1
AJ000474 mRNA Translation: CAA04113.1
AL391357 Genomic DNA No translation available.
BC054036 mRNA Translation: AAH54036.1
S52873 mRNA Translation: AAB24946.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS210.1

Protein sequence database of the Protein Information Resource

More...PIRi		I52710

NCBI Reference Sequences

More...RefSeqi		NP_001776.1, NM_001785.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000375071; ENSP00000364212; ENSG00000158825

Database of genes from NCBI RefSeq genomes

More...GeneIDi		978

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:978

UCSC genome browser

More...UCSCi		uc001bdk.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L27943 mRNA Translation: AAA57254.1
AF061658 AF061657 Genomic DNA Translation: AAD15828.1
AJ000474 mRNA Translation: CAA04113.1
AL391357 Genomic DNA No translation available.
BC054036 mRNA Translation: AAH54036.1
S52873 mRNA Translation: AAB24946.1
CCDSiCCDS210.1
PIRiI52710
RefSeqiNP_001776.1, NM_001785.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1MQ0X-ray2.40A/B11-146[»]
SMRiP32320
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi107416, 47 interactors
IntActiP32320, 26 interactors
STRINGi9606.ENSP00000364212

Chemistry databases

BindingDBiP32320
ChEMBLiCHEMBL4502
DrugBankiDB03185, 1-Beta-Ribofuranosyl-1,3-Diazepinone
DB00928, Azacitidine
DB01101, Capecitabine
DB15694, Cedazuridine
DB00987, Cytarabine
DB01262, Decitabine
DB00441, Gemcitabine
GuidetoPHARMACOLOGYi3133

PTM databases

iPTMnetiP32320
PhosphoSitePlusiP32320

Genetic variation databases

BioMutaiCDA
DMDMi1705718

Proteomic databases

EPDiP32320
jPOSTiP32320
MassIVEiP32320
MaxQBiP32320
PaxDbiP32320
PeptideAtlasiP32320
PRIDEiP32320
ProteomicsDBi54869
TopDownProteomicsiP32320

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		29806, 311 antibodies

The DNASU plasmid repository

More...DNASUi		978

Genome annotation databases

EnsembliENST00000375071; ENSP00000364212; ENSG00000158825
GeneIDi978
KEGGihsa:978
UCSCiuc001bdk.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		978
DisGeNETi978

GeneCards: human genes, protein and diseases

More...GeneCardsi		CDA
HGNCiHGNC:1712, CDA
HPAiENSG00000158825, Tissue enhanced (blood, bone marrow)
MIMi123920, gene
neXtProtiNX_P32320
OpenTargetsiENSG00000158825
PharmGKBiPA98
VEuPathDBiHostDB:ENSG00000158825.5

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0833, Eukaryota
GeneTreeiENSGT00390000000911
HOGENOMiCLU_097262_1_2_1
InParanoidiP32320
OMAiLTHFTCV
OrthoDBi1400471at2759
PhylomeDBiP32320
TreeFamiTF314486

Enzyme and pathway databases

BioCyciMetaCyc:HS08334-MONOMER
BRENDAi3.5.4.5, 2681
PathwayCommonsiP32320
ReactomeiR-HSA-6798695, Neutrophil degranulation
R-HSA-73614, Pyrimidine salvage
SABIO-RKiP32320

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		978, 8 hits in 985 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CDA, human
EvolutionaryTraceiP32320

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		Cytidine_deaminase

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		978
PharosiP32320, Tchem

Protein Ontology

More...PROi		PR:P32320
RNActiP32320, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000158825, Expressed in blood and 138 other tissues
GenevisibleiP32320, HS

Family and domain databases

InterProiView protein in InterPro
IPR016192, APOBEC/CMP_deaminase_Zn-bd
IPR002125, CMP_dCMP_dom
IPR006262, Cyt_deam_tetra
IPR016193, Cytidine_deaminase-like
PfamiView protein in Pfam
PF00383, dCMP_cyt_deam_1, 1 hit
SUPFAMiSSF53927, SSF53927, 1 hit
TIGRFAMsiTIGR01354, cyt_deam_tetra, 1 hit
PROSITEiView protein in PROSITE
PS00903, CYT_DCMP_DEAMINASES_1, 1 hit
PS51747, CYT_DCMP_DEAMINASES_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCDD_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P32320
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1996
Last modified: April 7, 2021
This is version 185 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families
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