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Entry version 183 (07 Oct 2020)
Sequence version 1 (01 Oct 1993)
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Protein

Vacuolar protein sorting/targeting protein VPS10

Gene

PEP1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. May execute multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment. Binds the Golgi-modified P2 form of CPY, and this interaction is dependent on the presence of an intact CPY vacuolar protein sorting signal.7 Publications

Miscellaneous

Present with 7210 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • nucleotide binding Source: UniProtKB-KW
  • signal sequence binding Source: SGD

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor
Biological processProtein transport, Transport
LigandNucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SCE-432722, Golgi Associated Vesicle Biogenesis

Protein family/group databases

Transport Classification Database

More...
TCDBi
9.A.63.1.1, the retromer-dependent vacuolar protein sorting (r-vps) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Vacuolar protein sorting/targeting protein VPS10
Alternative name(s):
Carboxypeptidase Y receptor
Short name:
CPY receptor
Carboxypeptidase Y-deficient protein 1
Sortilin VPS10
Vacuolar carboxypeptidase sorting receptor VPS10
Vacuolar protein sorting-associated protein 10
Vacuolar protein-targeting protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PEP1
Synonyms:VPS10, VPT1
Ordered Locus Names:YBL017C
ORF Names:YBL03.22, YBL0302
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:YBL017C

Saccharomyces Genome Database

More...
SGDi
S000000113, PEP1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini22 – 1397LumenalSequence analysisAdd BLAST1376
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1398 – 1414HelicalSequence analysisAdd BLAST17
Topological domaini1415 – 1579CytoplasmicSequence analysisAdd BLAST165

Keywords - Cellular componenti

Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002203722 – 1579Vacuolar protein sorting/targeting protein VPS10Add BLAST1558

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi96N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi170N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi447N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi793N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1010N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1303N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P32319

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P32319

PRoteomics IDEntifications database

More...
PRIDEi
P32319

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
32681, 205 interactors

Database of interacting proteins

More...
DIPi
DIP-5900N

Protein interaction database and analysis system

More...
IntActi
P32319, 25 interactors

Molecular INTeraction database

More...
MINTi
P32319

STRING: functional protein association networks

More...
STRINGi
4932.YBL017C

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P32319, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati57 – 68BNR 1Add BLAST12
Repeati101 – 112BNR 2Add BLAST12
Repeati179 – 190BNR 3Add BLAST12
Repeati415 – 426BNR 4Add BLAST12
Repeati487 – 498BNR 5Add BLAST12
Repeati533 – 544BNR 6Add BLAST12
Repeati764 – 775BNR 7Add BLAST12
Repeati861 – 872BNR 8Add BLAST12
Repeati1143 – 1154BNR 9Add BLAST12
Repeati1184 – 1195BNR 10Add BLAST12

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The lumenal domain contains two regions of approximately 650 AA that exhibit 20% identity. The cytoplasmic domain serves as a Golgi retention/recycling signal.3 Publications

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the VPS10-related sortilin family.Curated

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3511, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00990000203671

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000700_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P32319

Identification of Orthologs from Complete Genome Data

More...
OMAi
DNTCKLV

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036278, Sialidase_sf
IPR031777, Sortilin_C
IPR031778, Sortilin_N
IPR006581, VPS10
IPR015943, WD40/YVTN_repeat-like_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15902, Sortilin-Vps10, 2 hits
PF15901, Sortilin_C, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00602, VPS10, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50939, SSF50939, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P32319-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MILLHFVYSL WALLLIPLTN AEEFTPKVTK TIAQDSFDIL SFDDSNTLIR
60 70 80 90 100
KQDTSVTISF DDGETWEKVE GIEGEITWIY IDPFNRHDRA VATAMNGSYL
110 120 130 140 150
YITNDQGKSW ERITLPDSGE SISPRECYIE THPLNKNYFL AKCNYCEKTE
160 170 180 190 200
VNNDNEENSG DEEGQFEIFN ITRCTDKVFA SNDGGKSFSE IKSSLERNEN
210 220 230 240 250
SPISISDCGF AKTSKDSDLE SSDTSIICLF QNMQLIMDEF SSPYTESKLV
260 270 280 290 300
LTTDWGKSLK EFDQFKDKVV NGYRILKSHM VVLTQGDRYN DMSSMDVWVS
310 320 330 340 350
NDLSNFKMAY MPTQLRHSMQ GEIYEDAMGR IILPMSRERS DQEEDKGIVS
360 370 380 390 400
EILISDSQGL KFSPIPWTAN EVFGYINFYQ PTYLKGTMIA SLYPLSRRRN
410 420 430 440 450
RKGKAKGVKS KGVTKISVDN GLTWTMLKVV DPDNADSFDC DITDFENCSL
460 470 480 490 500
QNMFYTREGS TPTAGILMTT GIVGDGSVFD WGDQRTFISR DGGLTWKLAF
510 520 530 540 550
DFPCLYAVGD YGNVIVAIPY NADEDDDPQS EFYYSLDQGK TWTEYQLETT
560 570 580 590 600
IYPNEVMNTT PDGSGAKFIL NGFTLAHMDG TTNFIYAIDF STAFNDKTCE
610 620 630 640 650
ENDFEDWNLA EGKCVNGVKY KIRRRKQDAQ CLVKKVFEDL QLFETACDKC
660 670 680 690 700
TEADYECAFE FVRDATGKCV PDYNLIVLSD VCDKTKKKTV PVKPLQLVKG
710 720 730 740 750
DKCKKPMTVK SVDISCEGVP KKGTNDKEIV VTENKFDFKI QFYQYFDTVT
760 770 780 790 800
DESLLMINSR GEAYISHDGG QTIKRFDSNG ETIIEVVFNP YYNSSAYLFG
810 820 830 840 850
SKGSIFSTHD RGYSFMTAKL PEARQLGMPL DFNAKAQDTF IYYGGKNCES
860 870 880 890 900
ILSPECHAVA YLTNDGGETF TEMLDNAIHC EFAGSLFKYP SNEDMVMCQV
910 920 930 940 950
KEKSSQTRSL VSSTDFFQDD KNTVFENIIG YLSTGGYIIV AVPHENNELR
960 970 980 990 1000
AYVTIDGTEF AEAKFPYDED VGKQEAFTIL ESEKGSIFLH LATNLVPGRD
1010 1020 1030 1040 1050
FGNLLKSNSN GTSFVTLEHA VNRNTFGYVD FEKIQGLEGI ILTNIVSNSD
1060 1070 1080 1090 1100
KVAENKEDKQ LKTKITFNEG SDWNFLKPPK RDSEGKKFSC SSKSLDECSL
1110 1120 1130 1140 1150
HLHGYTERKD IRDTYSSGSA LGMMFGVGNV GPNLLPYKEC STFFTTDGGE
1160 1170 1180 1190 1200
TWAEVKKTPH QWEYGDHGGI LVLVPENSET DSISYSTDFG KTWKDYKFCA
1210 1220 1230 1240 1250
DKVLVKDITT VPRDSALRFL LFGEAADIGG SSFRTYTIDF RNIFERQCDF
1260 1270 1280 1290 1300
DITGKESADY KYSPLGSKSN CLFGHQTEFL RKTDENCFIG NIPLSEFSRN
1310 1320 1330 1340 1350
IKNCSCTRQD FECDYNFYKA NDGTCKLVKG LSPANAADVC KKEPDLIEYF
1360 1370 1380 1390 1400
ESSGYRKIPL STCEGGLKLD APSSPHACPG KEKEFKEKYS VSAGPFAFIF
1410 1420 1430 1440 1450
ISILLIIFFA AWFVYDRGIR RNGGFARFGE IRLGDDGLIE NNNTDRVVNN
1460 1470 1480 1490 1500
IVKSGFYVFS NIGSLLQHTK TNIAHAISKI RGRFGNRTGP SYSSLIHDQF
1510 1520 1530 1540 1550
LDEADDLLAG HDEDANDLSS FMDQGSNFEI EEDDVPTLEE EHTSYTDQPT
1560 1570
TTDVPDTLPE GNEENIDRPD STAPSNENQ
Length:1,579
Mass (Da):177,777
Last modified:October 1, 1993 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC778A0400612ECF4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti19T → I in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti38D → E in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti54T → A in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti74G → D in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti94 – 99AMNGSY → SMYESR in AAA18831 (PubMed:8187177).Curated6
Sequence conflicti119 – 126GESISPRE → EKNISSRG in AAA18831 (PubMed:8187177).Curated8
Sequence conflicti152 – 153Missing in AAA18831 (PubMed:8187177).Curated2
Sequence conflicti165 – 167QFE → APV in AAA18831 (PubMed:8187177).Curated3
Sequence conflicti202P → A in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti214S → G in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti283L → I in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti378F → L in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti410S → N in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti426M → V in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti774K → R in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti1089S → F in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti1266G → S in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti1476A → V in AAA18831 (PubMed:8187177).Curated1
Sequence conflicti1557T → A in AAA18831 (PubMed:8187177).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U07621 Unassigned DNA Translation: AAA18831.1
X68577 Genomic DNA Translation: CAA48568.1
Z35778 Genomic DNA Translation: CAA84836.1
BK006936 Genomic DNA Translation: DAA07103.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S25329

NCBI Reference Sequences

More...
RefSeqi
NP_009536.1, NM_001178257.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YBL017C_mRNA; YBL017C; YBL017C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
852264

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YBL017C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U07621 Unassigned DNA Translation: AAA18831.1
X68577 Genomic DNA Translation: CAA48568.1
Z35778 Genomic DNA Translation: CAA84836.1
BK006936 Genomic DNA Translation: DAA07103.1
PIRiS25329
RefSeqiNP_009536.1, NM_001178257.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi32681, 205 interactors
DIPiDIP-5900N
IntActiP32319, 25 interactors
MINTiP32319
STRINGi4932.YBL017C

Protein family/group databases

TCDBi9.A.63.1.1, the retromer-dependent vacuolar protein sorting (r-vps) family

Proteomic databases

MaxQBiP32319
PaxDbiP32319
PRIDEiP32319

Genome annotation databases

EnsemblFungiiYBL017C_mRNA; YBL017C; YBL017C
GeneIDi852264
KEGGisce:YBL017C

Organism-specific databases

EuPathDBiFungiDB:YBL017C
SGDiS000000113, PEP1

Phylogenomic databases

eggNOGiKOG3511, Eukaryota
GeneTreeiENSGT00990000203671
HOGENOMiCLU_000700_0_1_1
InParanoidiP32319
OMAiDNTCKLV

Enzyme and pathway databases

ReactomeiR-SCE-432722, Golgi Associated Vesicle Biogenesis

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P32319
RNActiP32319, protein

Family and domain databases

Gene3Di2.130.10.10, 3 hits
InterProiView protein in InterPro
IPR036278, Sialidase_sf
IPR031777, Sortilin_C
IPR031778, Sortilin_N
IPR006581, VPS10
IPR015943, WD40/YVTN_repeat-like_dom_sf
PfamiView protein in Pfam
PF15902, Sortilin-Vps10, 2 hits
PF15901, Sortilin_C, 2 hits
SMARTiView protein in SMART
SM00602, VPS10, 2 hits
SUPFAMiSSF50939, SSF50939, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVPS10_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P32319
Secondary accession number(s): D6VPY3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: October 7, 2020
This is version 183 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families
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