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Entry version 188 (08 May 2019)
Sequence version 1 (01 Oct 1993)
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Protein

Cholecystokinin receptor type A

Gene

CCKAR

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-416476 G alpha (q) signalling events

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
P32238

SIGNOR Signaling Network Open Resource

More...
SIGNORi
P32238

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cholecystokinin receptor type A
Short name:
CCK-A receptor
Short name:
CCK-AR
Alternative name(s):
Cholecystokinin-1 receptor
Short name:
CCK1-R
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCKAR
Synonyms:CCKRA
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:1570 CCKAR

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
118444 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P32238

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 41ExtracellularSequence analysisAdd BLAST41
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei42 – 67Helical; Name=1Sequence analysisAdd BLAST26
Topological domaini68 – 77CytoplasmicSequence analysis10
Transmembranei78 – 104Helical; Name=2Sequence analysisAdd BLAST27
Topological domaini105 – 115ExtracellularSequence analysisAdd BLAST11
Transmembranei116 – 137Helical; Name=3Sequence analysisAdd BLAST22
Topological domaini138 – 157CytoplasmicSequence analysisAdd BLAST20
Transmembranei158 – 178Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini179 – 210ExtracellularSequence analysisAdd BLAST32
Transmembranei211 – 234Helical; Name=5Sequence analysisAdd BLAST24
Topological domaini235 – 313CytoplasmicSequence analysisAdd BLAST79
Transmembranei314 – 334Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini335 – 349ExtracellularSequence analysisAdd BLAST15
Transmembranei350 – 373Helical; Name=7Sequence analysisAdd BLAST24
Topological domaini374 – 428CytoplasmicSequence analysisAdd BLAST55

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
886

Open Targets

More...
OpenTargetsi
ENSG00000163394

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA26142

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL1901

Drug and drug target database

More...
DrugBanki
DB00403 Ceruletide
DB04856 Dexloxiglumide
DB04867 Lintitript

IUPHAR/BPS Guide to PHARMACOLOGY

More...
GuidetoPHARMACOLOGYi
76

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCKAR

Domain mapping of disease mutations (DMDM)

More...
DMDMi
416772

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000692231 – 428Cholecystokinin receptor type AAdd BLAST428

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi10N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi18 ↔ 29PROSITE-ProRule annotation
Glycosylationi24N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi114 ↔ 196PROSITE-ProRule annotation
Glycosylationi190N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi387S-palmitoyl cysteineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, Lipoprotein, Palmitate

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P32238

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P32238

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P32238

PeptideAtlas

More...
PeptideAtlasi
P32238

PRoteomics IDEntifications database

More...
PRIDEi
P32238

ProteomicsDB human proteome resource

More...
ProteomicsDBi
54844

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P32238

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P32238

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000163394 Expressed in 37 organ(s), highest expression level in fundus of stomach

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P32238 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
107328, 1 interactor

Protein interaction database and analysis system

More...
IntActi
P32238, 1 interactor

Molecular INTeraction database

More...
MINTi
P32238

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000295589

Chemistry databases

BindingDB database of measured binding affinities

More...
BindingDBi
P32238

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1428
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1D6GNMR-A1-47[»]
1HZNNMR-A329-357[»]
1PB2model-A1-381[»]

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P32238

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P32238

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3656 Eukaryota
ENOG410XRW9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182743

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000294067

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P32238

KEGG Orthology (KO)

More...
KOi
K04194

Identification of Orthologs from Complete Genome Data

More...
OMAi
YEDGDGC

Database of Orthologous Groups

More...
OrthoDBi
1042780at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P32238

TreeFam database of animal gene trees

More...
TreeFami
TF315303

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.670.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009126 Cholcskin_rcpt
IPR000596 Cholcy_rcpt_A
IPR015276 CholecystokininA_recpt_N
IPR036472 CholecystokininA_recpt_N_sf
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00001 7tm_1, 1 hit
PF09193 CholecysA-Rec_N, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01822 CCYSTOKININR
PR00524 CCYSTOKNINAR
PR00237 GPCRRHODOPSN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P32238-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDVVDSLLVN GSNITPPCEL GLENETLFCL DQPRPSKEWQ PAVQILLYSL
60 70 80 90 100
IFLLSVLGNT LVITVLIRNK RMRTVTNIFL LSLAVSDLML CLFCMPFNLI
110 120 130 140 150
PNLLKDFIFG SAVCKTTTYF MGTSVSVSTF NLVAISLERY GAICKPLQSR
160 170 180 190 200
VWQTKSHALK VIAATWCLSF TIMTPYPIYS NLVPFTKNNN QTANMCRFLL
210 220 230 240 250
PNDVMQQSWH TFLLLILFLI PGIVMMVAYG LISLELYQGI KFEASQKKSA
260 270 280 290 300
KERKPSTTSS GKYEDSDGCY LQKTRPPRKL ELRQLSTGSS SRANRIRSNS
310 320 330 340 350
SAANLMAKKR VIRMLIVIVV LFFLCWMPIF SANAWRAYDT ASAERRLSGT
360 370 380 390 400
PISFILLLSY TSSCVNPIIY CFMNKRFRLG FMATFPCCPN PGPPGARGEV
410 420
GEEEEGGTTG ASLSRFSYSH MSASVPPQ
Length:428
Mass (Da):47,841
Last modified:October 1, 1993 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA6E8FABDA805E610
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L13605 mRNA Translation: AAA35659.1
L19315 mRNA Translation: AAA02819.1
U23430
, U23427, U23428, U23429 Genomic DNA Translation: AAA91123.1
D85606 Genomic DNA Translation: BAA90879.1
AY322549 mRNA Translation: AAP84362.1
AK313978 mRNA Translation: BAG36692.1
CH471069 Genomic DNA Translation: EAW92850.1
BC074987 mRNA Translation: AAH74987.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3438.1

Protein sequence database of the Protein Information Resource

More...
PIRi
JN0692

NCBI Reference Sequences

More...
RefSeqi
NP_000721.1, NM_000730.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000295589; ENSP00000295589; ENSG00000163394

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
886

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:886

UCSC genome browser

More...
UCSCi
uc003gse.2 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Wikipedia

Cholecystokinin receptor entry

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13605 mRNA Translation: AAA35659.1
L19315 mRNA Translation: AAA02819.1
U23430
, U23427, U23428, U23429 Genomic DNA Translation: AAA91123.1
D85606 Genomic DNA Translation: BAA90879.1
AY322549 mRNA Translation: AAP84362.1
AK313978 mRNA Translation: BAG36692.1
CH471069 Genomic DNA Translation: EAW92850.1
BC074987 mRNA Translation: AAH74987.1
CCDSiCCDS3438.1
PIRiJN0692
RefSeqiNP_000721.1, NM_000730.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1D6GNMR-A1-47[»]
1HZNNMR-A329-357[»]
1PB2model-A1-381[»]
SMRiP32238
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi107328, 1 interactor
IntActiP32238, 1 interactor
MINTiP32238
STRINGi9606.ENSP00000295589

Chemistry databases

BindingDBiP32238
ChEMBLiCHEMBL1901
DrugBankiDB00403 Ceruletide
DB04856 Dexloxiglumide
DB04867 Lintitript
GuidetoPHARMACOLOGYi76

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

PTM databases

iPTMnetiP32238
PhosphoSitePlusiP32238

Polymorphism and mutation databases

BioMutaiCCKAR
DMDMi416772

Proteomic databases

jPOSTiP32238
MaxQBiP32238
PaxDbiP32238
PeptideAtlasiP32238
PRIDEiP32238
ProteomicsDBi54844

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000295589; ENSP00000295589; ENSG00000163394
GeneIDi886
KEGGihsa:886
UCSCiuc003gse.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
886
DisGeNETi886

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCKAR

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0163965
HGNCiHGNC:1570 CCKAR
MIMi118444 gene
neXtProtiNX_P32238
OpenTargetsiENSG00000163394
PharmGKBiPA26142

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00950000182743
HOGENOMiHOG000294067
InParanoidiP32238
KOiK04194
OMAiYEDGDGC
OrthoDBi1042780at2759
PhylomeDBiP32238
TreeFamiTF315303

Enzyme and pathway databases

ReactomeiR-HSA-375276 Peptide ligand-binding receptors
R-HSA-416476 G alpha (q) signalling events
SignaLinkiP32238
SIGNORiP32238

Miscellaneous databases

EvolutionaryTraceiP32238

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
Cholecystokinin_A_receptor

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
886

Protein Ontology

More...
PROi
PR:P32238

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000163394 Expressed in 37 organ(s), highest expression level in fundus of stomach
GenevisibleiP32238 HS

Family and domain databases

Gene3Di4.10.670.10, 1 hit
InterProiView protein in InterPro
IPR009126 Cholcskin_rcpt
IPR000596 Cholcy_rcpt_A
IPR015276 CholecystokininA_recpt_N
IPR036472 CholecystokininA_recpt_N_sf
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PF09193 CholecysA-Rec_N, 1 hit
PRINTSiPR01822 CCYSTOKININR
PR00524 CCYSTOKNINAR
PR00237 GPCRRHODOPSN
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCKAR_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P32238
Secondary accession number(s): B2R9Z5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: May 8, 2019
This is version 188 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
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