Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60S ribosomal protein L7

Gene

RpL7

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic translation Source: FlyBase
  • maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: GO_Central
  • pupariation Source: FlyBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding

Enzyme and pathway databases

ReactomeiR-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DME-72689 Formation of a pool of free 40S subunits
R-DME-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DME-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L7
Gene namesi
Name:RpL7
ORF Names:CG4897
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0005593 RpL7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001046381 – 25260S ribosomal protein L7Add BLAST252

Proteomic databases

PaxDbiP32100
PRIDEiP32100

Expressioni

Gene expression databases

BgeeiFBgn0005593
ExpressionAtlasiP32100 baseline and differential
GenevisibleiP32100 DM

Interactioni

Protein-protein interaction databases

BioGridi60443, 20 interactors
DIPiDIP-18002N
IntActiP32100, 2 interactors
MINTiP32100
STRINGi7227.FBpp0079536

Structurei

3D structure databases

ProteinModelPortaliP32100
SMRiP32100
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3184 Eukaryota
COG1841 LUCA
InParanoidiP32100
KOiK02937
OMAiPTGGWRT
OrthoDBiEOG091G0IHS
PhylomeDBiP32100

Family and domain databases

CDDicd01657 Ribosomal_L7_archeal_euk, 1 hit
Gene3Di1.10.15.30, 1 hit
3.30.1390.20, 2 hits
InterProiView protein in InterPro
IPR036919 L30_ferredoxin-like_sf
IPR023106 Ribosomal_L30_central_dom_arc
IPR018038 Ribosomal_L30_CS
IPR016082 Ribosomal_L30_ferredoxin-like
IPR012988 Ribosomal_L30_N
IPR005998 Ribosomal_L7_euk
IPR035808 Ribosomal_L7_euk_arc
PfamiView protein in Pfam
PF00327 Ribosomal_L30, 1 hit
PF08079 Ribosomal_L30_N, 1 hit
SUPFAMiSSF55129 SSF55129, 1 hit
TIGRFAMsiTIGR01310 uL30_euk, 1 hit
PROSITEiView protein in PROSITE
PS00634 RIBOSOMAL_L30, 1 hit

Sequencei

Sequence statusi: Complete.

P32100-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAPVVKKPA AKKLPAVPES KLKFSKKQIS KRVAESKRRL KKAAVIALRK
60 70 80 90 100
KENLVRAEKY QNEYIKAEQR EIKLRRLAKK RNQFYVPAEA KLAFVVRIRG
110 120 130 140 150
INKVAPKVRK VLQLFRLRQI NNGVFIKLNK ATINMLRIAE PYITWGYPNL
160 170 180 190 200
KSVRELIYKR GFVKHNRQRV PITDNFVIER KLRQAHQIQC VEDLVHEIFT
210 220 230 240 250
VGPNFKYASN FLWPFKLNTP TGGWRKKANH YVNGGDFGNR EDQINRLLRK

MV
Length:252
Mass (Da):29,552
Last modified:February 21, 2001 - v2
Checksum:i958439D03E83EB44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF52868.1
AY089648 mRNA Translation: AAL90386.1
X15109 mRNA Translation: CAA33207.1
PIRiS21500
RefSeqiNP_001285794.1, NM_001298865.1
NP_523531.1, NM_078807.3
UniGeneiDm.3483

Genome annotation databases

EnsemblMetazoaiFBtr0079946; FBpp0079536; FBgn0005593
FBtr0343653; FBpp0310250; FBgn0005593
GeneIDi34352
KEGGidme:Dmel_CG4897

Similar proteinsi

Entry informationi

Entry nameiRL7_DROME
AccessioniPrimary (citable) accession number: P32100
Secondary accession number(s): Q541C8, Q9VL30
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: February 21, 2001
Last modified: May 23, 2018
This is version 140 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health