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Protein

Inner membrane ABC transporter ATP-binding protein YddA

Gene

yddA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi400 – 407ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:YDDA-MONOMER

Protein family/group databases

TCDBi3.A.1.203.11 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane ABC transporter ATP-binding protein YddA
Alternative name(s):
CDS102
Gene namesi
Name:yddA
Ordered Locus Names:b1496, JW5242
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11742 yddA

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 3CytoplasmicSequence analysis3
Transmembranei4 – 24HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini25 – 31PeriplasmicSequence analysis7
Transmembranei32 – 52HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini53 – 70CytoplasmicSequence analysisAdd BLAST18
Transmembranei71 – 91HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini92 – 151PeriplasmicSequence analysisAdd BLAST60
Transmembranei152 – 172HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini173 – 187CytoplasmicSequence analysisAdd BLAST15
Transmembranei188 – 208HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini209 – 290PeriplasmicSequence analysisAdd BLAST82
Transmembranei291 – 311HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini312 – 561CytoplasmicSequence analysisAdd BLAST250

GO - Cellular componenti

  • integral component of membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000931631 – 561Inner membrane ABC transporter ATP-binding protein YddAAdd BLAST561

Proteomic databases

PaxDbiP31826
PRIDEiP31826

Interactioni

Protein-protein interaction databases

BioGridi4260785, 211 interactors
STRINGi316385.ECDH10B_1627

Structurei

3D structure databases

ProteinModelPortaliP31826
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 337ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST303
Domaini367 – 561ABC transporterPROSITE-ProRule annotationAdd BLAST195

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CQ0 Bacteria
COG4178 LUCA
HOGENOMiHOG000255118
InParanoidiP31826
KOiK02471
OMAiSMMAYLI
PhylomeDBiP31826

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF06472 ABC_membrane_2, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

P31826-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITIPITLRM LIAKYLCLLK PFWLRKNNKT SVLLIIIILA MILGVVKIQV
60 70 80 90 100
WLNDWNNDFF NALSQKETDK LWQLVLWFPA LLGIFVLISV NKTWLIKLLT
110 120 130 140 150
IRWREWLTDY YLNRWFADKN YYFTQIYGEH KNTDNPDQRI AEDILLLISK
160 170 180 190 200
TLSLSFGFIQ SLSMLITFTV ILWESAGTLS FTVGGTEWNI QGYMVYTVVL
210 220 230 240 250
IVIGGTLFTH KVGKRIRPLN VEKQRSEATF RTNLVQHNKQ AELIALSNAE
260 270 280 290 300
SLQRQELSDN FHTIKENWHR LMNRQRWLDY WQNIYSRSLS VLPYFLLLPQ
310 320 330 340 350
FISGQINLGG LMKSRQAFML VSNNLSWFIY KYDELAELAA VIDRLYEFHQ
360 370 380 390 400
LTEQRPTNKP KNCQHAVQVA DASIRTPDNK IILENLNFHV SPGKWLLLKG
410 420 430 440 450
YSGAGKTTLL KTLSHCWPWF KGDISSPADS WYVSQTPLIK TGLLKEIICK
460 470 480 490 500
ALPLPVDDKS LSEVLHQVGL GKLAARIHDH DRWGDILSSG EKQRIALARL
510 520 530 540 550
ILRRPKWIFL DETTSHLEEQ EAIRLLRLVR EKLPTSGVIM VTHQPGVWNL
560
ADDICDISAV L
Length:561
Mass (Da):64,985
Last modified:November 1, 1997 - v2
Checksum:i92E47426294413F5
GO

Sequence cautioni

The sequence CAA50732 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74569.1
AP009048 Genomic DNA Translation: BAA15167.2
X71917 Genomic DNA Translation: CAA50732.1 Different initiation.
PIRiC64903
RefSeqiNP_416013.1, NC_000913.3
WP_000628576.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74569; AAC74569; b1496
BAA15167; BAA15167; BAA15167
GeneIDi945945
KEGGiecj:JW5242
eco:b1496
PATRICifig|1411691.4.peg.770

Similar proteinsi

Entry informationi

Entry nameiYDDA_ECOLI
AccessioniPrimary (citable) accession number: P31826
Secondary accession number(s): P76133, P76876
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1997
Last modified: July 18, 2018
This is version 141 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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