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Protein

Uncharacterized oxidoreductase YciK

Gene

yciK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei152SubstrateBy similarity1
Active sitei165Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi16 – 40NADPBy similarityAdd BLAST25

GO - Molecular functioni

  • oxidoreductase activity Source: GO_Central

Keywordsi

Molecular functionOxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:EG11759-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YciK (EC:1.-.-.-)
Gene namesi
Name:yciK
Ordered Locus Names:b1271, JW1263
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11759 yciK

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000548241 – 252Uncharacterized oxidoreductase YciKAdd BLAST252

Proteomic databases

EPDiP31808
PaxDbiP31808
PRIDEiP31808

Interactioni

Protein-protein interaction databases

BioGridi4259576, 48 interactors
IntActiP31808, 6 interactors
STRINGi316385.ECDH10B_1386

Structurei

Secondary structure

1252
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP31808
SMRiP31808
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP31808

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105UBK Bacteria
COG1028 LUCA
InParanoidiP31808
PhylomeDBiP31808

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR020904 Sc_DH/Rdtase_CS
IPR002347 SDR_fam
PfamiView protein in Pfam
PF00106 adh_short, 1 hit
PRINTSiPR00081 GDHRDH
SUPFAMiSSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00061 ADH_SHORT, 1 hit

Sequencei

Sequence statusi: Complete.

P31808-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHYQPKQDLL NDRIILVTGA SDGIGREAAM TYARYGATVI LLGRNEEKLR
60 70 80 90 100
QVASHINEET GRQPQWFILD LLTCTSENCQ QLAQRIAVNY PRLDGVLHNA
110 120 130 140 150
GLLGDVCPMS EQNPQVWQDV MQVNVNATFM LTQALLPLLL KSDAGSLVFT
160 170 180 190 200
SSSVGRQGRA NWGAYAASKF ATEGMMQVLA DEYQQRLRVN CINPGGTRTA
210 220 230 240 250
MRASAFPTED PQKLKTPADI MPLYLWLMGD DSRRKTGMTF DAQPGRKPGI

SQ
Length:252
Mass (Da):27,933
Last modified:November 1, 1997 - v3
Checksum:i4F7D860BF8840F7A
GO

Sequence cautioni

The sequence AAB59991 differs from that shown. Reason: Frameshift at position 115.Curated
The sequence AAB59992 differs from that shown. Reason: Frameshift at position 115.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti63Q → P (PubMed:1885549).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74353.1
AP009048 Genomic DNA Translation: BAA14808.1
U17433 Genomic DNA Translation: AAB59992.1 Frameshift.
U17433 Genomic DNA Translation: AAB59991.1 Frameshift.
M73320 Genomic DNA No translation available.
PIRiB64875
RefSeqiNP_415787.1, NC_000913.3
WP_000559286.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74353; AAC74353; b1271
BAA14808; BAA14808; BAA14808
GeneIDi945838
KEGGiecj:JW1263
eco:b1271
PATRICifig|1411691.4.peg.1013

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74353.1
AP009048 Genomic DNA Translation: BAA14808.1
U17433 Genomic DNA Translation: AAB59992.1 Frameshift.
U17433 Genomic DNA Translation: AAB59991.1 Frameshift.
M73320 Genomic DNA No translation available.
PIRiB64875
RefSeqiNP_415787.1, NC_000913.3
WP_000559286.1, NZ_LN832404.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3E9QX-ray1.70A/B1-252[»]
3F1KX-ray2.60A1-252[»]
3F1LX-ray0.95A/B1-252[»]
ProteinModelPortaliP31808
SMRiP31808
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259576, 48 interactors
IntActiP31808, 6 interactors
STRINGi316385.ECDH10B_1386

Proteomic databases

EPDiP31808
PaxDbiP31808
PRIDEiP31808

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74353; AAC74353; b1271
BAA14808; BAA14808; BAA14808
GeneIDi945838
KEGGiecj:JW1263
eco:b1271
PATRICifig|1411691.4.peg.1013

Organism-specific databases

EchoBASEiEB1709
EcoGeneiEG11759 yciK

Phylogenomic databases

eggNOGiENOG4105UBK Bacteria
COG1028 LUCA
InParanoidiP31808
PhylomeDBiP31808

Enzyme and pathway databases

BioCyciEcoCyc:EG11759-MONOMER

Miscellaneous databases

EvolutionaryTraceiP31808
PROiPR:P31808

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR020904 Sc_DH/Rdtase_CS
IPR002347 SDR_fam
PfamiView protein in Pfam
PF00106 adh_short, 1 hit
PRINTSiPR00081 GDHRDH
SUPFAMiSSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00061 ADH_SHORT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiYCIK_ECOLI
AccessioniPrimary (citable) accession number: P31808
Secondary accession number(s): P77516
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1997
Last modified: November 7, 2018
This is version 132 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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