UniProtKB - P31808 (YCIK_ECOLI)
Protein
Uncharacterized oxidoreductase YciK
Gene
yciK
Organism
Escherichia coli (strain K12)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 152 | SubstrateBy similarity | 1 | |
Active sitei | 165 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 16 – 40 | NADPBy similarityAdd BLAST | 25 |
GO - Molecular functioni
- oxidoreductase activity Source: GO_Central
Keywordsi
Molecular function | Oxidoreductase |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11759-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:yciK Ordered Locus Names:b1271, JW1263 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000054824 | 1 – 252 | Uncharacterized oxidoreductase YciKAdd BLAST | 252 |
Proteomic databases
jPOSTi | P31808 |
PaxDbi | P31808 |
PRIDEi | P31808 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4259576, 48 interactors |
IntActi | P31808, 6 interactors |
STRINGi | 511145.b1271 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P31808 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P31808 |
Family & Domainsi
Sequence similaritiesi
Belongs to the short-chain dehydrogenases/reductases (SDR) family.Curated
Phylogenomic databases
eggNOGi | COG1028, Bacteria |
HOGENOMi | CLU_010194_2_10_6 |
InParanoidi | P31808 |
PhylomeDBi | P31808 |
Family and domain databases
InterProi | View protein in InterPro IPR036291, NAD(P)-bd_dom_sf IPR020904, Sc_DH/Rdtase_CS IPR002347, SDR_fam |
Pfami | View protein in Pfam PF00106, adh_short, 1 hit |
PRINTSi | PR00081, GDHRDH |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00061, ADH_SHORT, 1 hit |
i Sequence
Sequence statusi: Complete.
P31808-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MHYQPKQDLL NDRIILVTGA SDGIGREAAM TYARYGATVI LLGRNEEKLR
60 70 80 90 100
QVASHINEET GRQPQWFILD LLTCTSENCQ QLAQRIAVNY PRLDGVLHNA
110 120 130 140 150
GLLGDVCPMS EQNPQVWQDV MQVNVNATFM LTQALLPLLL KSDAGSLVFT
160 170 180 190 200
SSSVGRQGRA NWGAYAASKF ATEGMMQVLA DEYQQRLRVN CINPGGTRTA
210 220 230 240 250
MRASAFPTED PQKLKTPADI MPLYLWLMGD DSRRKTGMTF DAQPGRKPGI
SQ
Sequence cautioni
The sequence AAB59991 differs from that shown. Reason: Frameshift.Curated
The sequence AAB59992 differs from that shown. Reason: Frameshift.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 63 | Q → P (PubMed:1885549).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74353.1 AP009048 Genomic DNA Translation: BAA14808.1 U17433 Genomic DNA Translation: AAB59992.1 Frameshift. U17433 Genomic DNA Translation: AAB59991.1 Frameshift. M73320 Genomic DNA No translation available. |
PIRi | B64875 |
RefSeqi | NP_415787.1, NC_000913.3 WP_000559286.1, NZ_SSZK01000031.1 |
Genome annotation databases
EnsemblBacteriai | AAC74353; AAC74353; b1271 BAA14808; BAA14808; BAA14808 |
GeneIDi | 945838 |
KEGGi | ecj:JW1263 eco:b1271 |
PATRICi | fig|1411691.4.peg.1013 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74353.1 AP009048 Genomic DNA Translation: BAA14808.1 U17433 Genomic DNA Translation: AAB59992.1 Frameshift. U17433 Genomic DNA Translation: AAB59991.1 Frameshift. M73320 Genomic DNA No translation available. |
PIRi | B64875 |
RefSeqi | NP_415787.1, NC_000913.3 WP_000559286.1, NZ_SSZK01000031.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3E9Q | X-ray | 1.70 | A/B | 1-252 | [»] | |
3F1K | X-ray | 2.60 | A | 1-252 | [»] | |
3F1L | X-ray | 0.95 | A/B | 1-252 | [»] | |
SMRi | P31808 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 4259576, 48 interactors |
IntActi | P31808, 6 interactors |
STRINGi | 511145.b1271 |
Proteomic databases
jPOSTi | P31808 |
PaxDbi | P31808 |
PRIDEi | P31808 |
Genome annotation databases
EnsemblBacteriai | AAC74353; AAC74353; b1271 BAA14808; BAA14808; BAA14808 |
GeneIDi | 945838 |
KEGGi | ecj:JW1263 eco:b1271 |
PATRICi | fig|1411691.4.peg.1013 |
Organism-specific databases
EchoBASEi | EB1709 |
Phylogenomic databases
eggNOGi | COG1028, Bacteria |
HOGENOMi | CLU_010194_2_10_6 |
InParanoidi | P31808 |
PhylomeDBi | P31808 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11759-MONOMER |
Miscellaneous databases
EvolutionaryTracei | P31808 |
PROi | PR:P31808 |
Family and domain databases
InterProi | View protein in InterPro IPR036291, NAD(P)-bd_dom_sf IPR020904, Sc_DH/Rdtase_CS IPR002347, SDR_fam |
Pfami | View protein in Pfam PF00106, adh_short, 1 hit |
PRINTSi | PR00081, GDHRDH |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00061, ADH_SHORT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YCIK_ECOLI | |
Accessioni | P31808Primary (citable) accession number: P31808 Secondary accession number(s): P77516 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1993 |
Last sequence update: | November 1, 1997 | |
Last modified: | April 7, 2021 | |
This is version 147 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families