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UniProtKB - P31679 (YAAU_ECOLI)
Protein
Putative metabolite transport protein YaaU
Gene
yaaU
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
GO - Biological processi
- response to oxidative stress Source: EcoCyc
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:YAAU-MONOMER |
Protein family/group databases
TCDBi | 2.A.1.1.114, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: Putative metabolite transport protein YaaU |
Gene namesi | Name:yaaU Synonyms:yabE Ordered Locus Names:b0045, JW0044 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell inner membrane Curated; Multi-pass membrane protein Curated
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 18 | CytoplasmicSequence analysisAdd BLAST | 18 | |
Transmembranei | 19 – 39 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 40 – 53 | PeriplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 54 – 74 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 75 – 84 | CytoplasmicSequence analysis | 10 | |
Transmembranei | 85 – 105 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 106 – 113 | PeriplasmicSequence analysis | 8 | |
Transmembranei | 114 – 134 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 135 – 145 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 146 – 166 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 167 – 173 | PeriplasmicSequence analysis | 7 | |
Transmembranei | 174 – 194 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 195 – 241 | CytoplasmicSequence analysisAdd BLAST | 47 | |
Transmembranei | 242 – 262 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Topological domaini | 263 – 282 | PeriplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 283 – 303 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Topological domaini | 304 – 309 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 310 – 329 | Helical; Name=9Sequence analysisAdd BLAST | 20 | |
Topological domaini | 330 – 334 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 335 – 357 | Helical; Name=10Sequence analysisAdd BLAST | 23 | |
Topological domaini | 358 – 373 | CytoplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 374 – 394 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Topological domaini | 395 – 401 | PeriplasmicSequence analysis | 7 | |
Transmembranei | 402 – 422 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 423 – 443 | CytoplasmicSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050481 | 1 – 443 | Putative metabolite transport protein YaaUAdd BLAST | 443 |
Proteomic databases
PaxDbi | P31679 |
PRIDEi | P31679 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262202, 181 interactors |
STRINGi | 511145.b0045 |
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2271, Bacteria |
HOGENOMi | CLU_001265_46_6_6 |
InParanoidi | P31679 |
PhylomeDBi | P31679 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
P31679-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQPSRNFDDL KFSSIHRRIL LWGSGGPFLD GYVLVMIGVA LEQLTPALKL
60 70 80 90 100
DADWIGLLGA GTLAGLFVGT SLFGYISDKV GRRKMFLIDI IAIGVISVAT
110 120 130 140 150
MFVSSPVELL VMRVLIGIVI GADYPIATSM ITEFSSTRQR AFSISFIAAM
160 170 180 190 200
WYVGATCADL VGYWLYDVEG GWRWMLGSAA IPCLLILIGR FELPESPRWL
210 220 230 240 250
LRKGRVKECE EMMIKLFGEP VAFDEEQPQQ TRFRDLFNRR HFPFVLFVAA
260 270 280 290 300
IWTCQVIPMF AIYTFGPQIV GLLGLGVGKN AALGNVVISL FFMLGCIPPM
310 320 330 340 350
LWLNTAGRRP LLIGSFAMMT LALAVLGLIP DMGIWLVVMA FAVYAFFSGG
360 370 380 390 400
PGNLQWLYPN ELFPTDIRAS AVGVIMSLSR IGTIVSTWAL PIFINNYGIS
410 420 430 440
NTMLMGAGIS LFGLLISVAF APETRGMSLA QTSNMTIRGQ RMG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC73156.1 AP009048 Genomic DNA Translation: BAB96613.2 |
PIRi | E64725 |
RefSeqi | NP_414587.1, NC_000913.3 WP_001183198.1, NZ_STEB01000010.1 |
Genome annotation databases
EnsemblBacteriai | AAC73156; AAC73156; b0045 BAB96613; BAB96613; BAB96613 |
GeneIDi | 66671665 944766 |
KEGGi | ecj:JW0044 eco:b0045 |
PATRICi | fig|1411691.4.peg.2238 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC73156.1 AP009048 Genomic DNA Translation: BAB96613.2 |
PIRi | E64725 |
RefSeqi | NP_414587.1, NC_000913.3 WP_001183198.1, NZ_STEB01000010.1 |
3D structure databases
SMRi | P31679 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4262202, 181 interactors |
STRINGi | 511145.b0045 |
Protein family/group databases
TCDBi | 2.A.1.1.114, the major facilitator superfamily (mfs) |
Proteomic databases
PaxDbi | P31679 |
PRIDEi | P31679 |
Genome annotation databases
EnsemblBacteriai | AAC73156; AAC73156; b0045 BAB96613; BAB96613; BAB96613 |
GeneIDi | 66671665 944766 |
KEGGi | ecj:JW0044 eco:b0045 |
PATRICi | fig|1411691.4.peg.2238 |
Organism-specific databases
EchoBASEi | EB1527 |
Phylogenomic databases
eggNOGi | COG2271, Bacteria |
HOGENOMi | CLU_001265_46_6_6 |
InParanoidi | P31679 |
PhylomeDBi | P31679 |
Enzyme and pathway databases
BioCyci | EcoCyc:YAAU-MONOMER |
Miscellaneous databases
PROi | PR:P31679 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YAAU_ECOLI | |
Accessioni | P31679Primary (citable) accession number: P31679 Secondary accession number(s): P31578, P75628 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1993 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 159 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families