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Entry version 122 (12 Aug 2020)
Sequence version 1 (01 Jul 1993)
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Protein

Sodium-dependent neutral amino acid transporter SLC6A17

Gene

Slc6a17

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent.1 Publication

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=1.72 mM for glycine1 Publication
  2. KM=0.86 mM for proline1 Publication
  1. Vmax=199 pmol/min/mg enzyme for glycine1 Publication
  2. Vmax=172 pmol/min/mg enzyme for proline1 Publication

pH dependencei

Optimum pH is 8.5.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processNeurotransmitter transport, Symport, Transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.22.6.2, the neurotransmitter:sodium symporter (nss) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium-dependent neutral amino acid transporter SLC6A17
Alternative name(s):
Sodium-dependent neurotransmitter transporter NTT4
Solute carrier family 6 member 17
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Slc6a17
Synonyms:Ntt4, Rxt1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Rat genome database

More...
RGDi
1587185, Slc6a17

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 68CytoplasmicSequence analysisAdd BLAST68
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei69 – 89Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini90 – 96ExtracellularSequence analysis7
Transmembranei97 – 116Helical; Name=2Sequence analysisAdd BLAST20
Topological domaini117 – 140CytoplasmicSequence analysisAdd BLAST24
Transmembranei141 – 161Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini162 – 224ExtracellularSequence analysisAdd BLAST63
Transmembranei225 – 243Helical; Name=4Sequence analysisAdd BLAST19
Topological domaini244 – 251CytoplasmicSequence analysis8
Transmembranei252 – 269Helical; Name=5Sequence analysisAdd BLAST18
Topological domaini270 – 304ExtracellularSequence analysisAdd BLAST35
Transmembranei305 – 322Helical; Name=6Sequence analysisAdd BLAST18
Topological domaini323 – 333CytoplasmicSequence analysisAdd BLAST11
Transmembranei334 – 355Helical; Name=7Sequence analysisAdd BLAST22
Topological domaini356 – 451ExtracellularSequence analysisAdd BLAST96
Transmembranei452 – 471Helical; Name=8Sequence analysisAdd BLAST20
Topological domaini472 – 494CytoplasmicSequence analysisAdd BLAST23
Transmembranei495 – 513Helical; Name=9Sequence analysisAdd BLAST19
Topological domaini514 – 528ExtracellularSequence analysisAdd BLAST15
Transmembranei529 – 549Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini550 – 569CytoplasmicSequence analysisAdd BLAST20
Transmembranei570 – 591Helical; Name=11Sequence analysisAdd BLAST22
Topological domaini592 – 618ExtracellularSequence analysisAdd BLAST27
Transmembranei619 – 641Helical; Name=12Sequence analysisAdd BLAST23
Topological domaini642 – 727CytoplasmicSequence analysisAdd BLAST86

Keywords - Cellular componenti

Cell junction, Cell projection, Cytoplasmic vesicle, Membrane, Synapse

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002148051 – 727Sodium-dependent neutral amino acid transporter SLC6A17Add BLAST727

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei13PhosphoserineBy similarity1
Modified residuei20PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi186N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei377PhosphotyrosineBy similarity1
Glycosylationi393N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei665PhosphoserineCombined sources1
Modified residuei701PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P31662

PRoteomics IDEntifications database

More...
PRIDEi
P31662

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
P31662, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P31662

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P31662

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P31662

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Found exclusively in the central nervous system and is more abundant in the cerebellum and the cerebral cortex. Expressed in PC-12 cell line.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000050090, Expressed in frontal cortex and 21 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P31662, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
565981, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000065179

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3659, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156542

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006855_7_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P31662

KEGG Orthology (KO)

More...
KOi
K05048

Identification of Orthologs from Complete Genome Data

More...
OMAi
QDEQRFI

Database of Orthologous Groups

More...
OrthoDBi
250396at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P31662

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000175, Na/ntran_symport
IPR002438, Neutral_aa_SLC6
IPR037272, SNS_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11616, PTHR11616, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00209, SNF, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00176, NANEUSMPORT
PR01206, ORPHTRNSPORT

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF161070, SSF161070, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00610, NA_NEUROTRAN_SYMP_1, 1 hit
PS00754, NA_NEUROTRAN_SYMP_2, 1 hit
PS50267, NA_NEUROTRAN_SYMP_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P31662-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPKNSKVTQR EHSNEHVTES VADLLALEEP VDYKQSVLNV AGETGGKQKV
60 70 80 90 100
AEEELDAEDR PAWNSKLQYI LAQIGFSVGL GNIWRFPYLC QKNGGGAYLV
110 120 130 140 150
PYLVLLIIIG IPLFFLELAV GQRIRRGSIG VWHYVCPRLG GIGFSSCIVC
160 170 180 190 200
LFVGLYYNVI IGWSVFYFFK SFQYPLPWSE CPVIRNGTVA VVEPECEKSS
210 220 230 240 250
ATTYFWYREA LDISNSISES GGLNWKMTVC LLVAWSIVGM AVVKGIQSSG
260 270 280 290 300
KVMYFSSLFP YVVLACFLVR GLLLRGAVDG ILHMFTPKLD KMLDPQVWRE
310 320 330 340 350
AATQVFFALG LGFGGVIAFS SYNKQDNNCH FDAALVSFIN FFTSVLATLV
360 370 380 390 400
VFAVLGFKAN IMNEKCVVEN AEKILGYLNS NVLSRDLIPP HVNFSHLTTK
410 420 430 440 450
DYSEMYNVIM TVKEKQFSAL GLDPCLLEDE LDKSVQGTGL AFIAFTEAMT
460 470 480 490 500
HFPASPFWSV MFFLMLINLG LGSMIGTMAG ITTPIIDTFK VPKEMFTVGC
510 520 530 540 550
CVFAFFVGLL FVQRSGNYFV TMFDDYSATL PLTVIVILEN IAVAWIYGTK
560 570 580 590 600
KFMQELTEML GFRPYRFYFY MWKFVSPLCM AVLTTASIIQ LGVSPPGYSA
610 620 630 640 650
WIKEEAAERY LYFPNWAMAL LITLIAVATL PIPVVFILRH FHLLSDGSNT
660 670 680 690 700
LSVSYKKGRM MKDISNLEEN DETRFILSKV PSEAPSPMPT HRSYLGPGST
710 720
SPLESSSHPN GRYGSGYLLA STPESEL
Length:727
Mass (Da):81,055
Last modified:July 1, 1993 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC676048C0A6BDF7C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti261Y → C in AAC60673 (PubMed:8294906).Curated1
Sequence conflicti499G → S in AAC60673 (PubMed:8294906).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L06434 mRNA Translation: AAB24776.1
S68944 mRNA Translation: AAC60673.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I56506
S27043

NCBI Reference Sequences

More...
RefSeqi
NP_001028251.1, NM_001033079.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000075653; ENSRNOP00000065179; ENSRNOG00000050090

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
613226

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:613226

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L06434 mRNA Translation: AAB24776.1
S68944 mRNA Translation: AAC60673.1
PIRiI56506
S27043
RefSeqiNP_001028251.1, NM_001033079.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi565981, 1 interactor
STRINGi10116.ENSRNOP00000065179

Protein family/group databases

TCDBi2.A.22.6.2, the neurotransmitter:sodium symporter (nss) family

PTM databases

GlyGeniP31662, 2 sites
iPTMnetiP31662
PhosphoSitePlusiP31662
SwissPalmiP31662

Proteomic databases

PaxDbiP31662
PRIDEiP31662

Genome annotation databases

EnsembliENSRNOT00000075653; ENSRNOP00000065179; ENSRNOG00000050090
GeneIDi613226
KEGGirno:613226

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
388662
RGDi1587185, Slc6a17

Phylogenomic databases

eggNOGiKOG3659, Eukaryota
GeneTreeiENSGT00940000156542
HOGENOMiCLU_006855_7_1_1
InParanoidiP31662
KOiK05048
OMAiQDEQRFI
OrthoDBi250396at2759
PhylomeDBiP31662

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P31662

Gene expression databases

BgeeiENSRNOG00000050090, Expressed in frontal cortex and 21 other tissues
GenevisibleiP31662, RN

Family and domain databases

InterProiView protein in InterPro
IPR000175, Na/ntran_symport
IPR002438, Neutral_aa_SLC6
IPR037272, SNS_sf
PANTHERiPTHR11616, PTHR11616, 1 hit
PfamiView protein in Pfam
PF00209, SNF, 1 hit
PRINTSiPR00176, NANEUSMPORT
PR01206, ORPHTRNSPORT
SUPFAMiSSF161070, SSF161070, 1 hit
PROSITEiView protein in PROSITE
PS00610, NA_NEUROTRAN_SYMP_1, 1 hit
PS00754, NA_NEUROTRAN_SYMP_2, 1 hit
PS50267, NA_NEUROTRAN_SYMP_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS6A17_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P31662
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: August 12, 2020
This is version 122 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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