UniProtKB - P31460 (DGOR_ECOLI)
Protein
Galactonate operon transcriptional repressor
Gene
dgoR
Organism
Escherichia coli (strain K12)
Status
Functioni
Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 31 – 50 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 20 |
GO - Molecular functioni
- bacterial-type cis-regulatory region sequence-specific DNA binding Source: EcoCyc
- bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding Source: EcoCyc
- DNA binding Source: EcoCyc
- DNA-binding transcription repressor activity Source: EcoCyc
- identical protein binding Source: EcoCyc
- ligand-activated transcription factor activity Source: EcoCyc
GO - Biological processi
- negative regulation of cellular carbohydrate metabolic process Source: EcoCyc
- negative regulation of DNA-templated transcription, initiation Source: EcoCyc
- regulation of transcription, DNA-templated Source: EcoCyc
Keywordsi
Molecular function | DNA-binding, Repressor |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
BioCyci | EcoCyc:G7790-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Galactonate operon transcriptional repressor |
Gene namesi | Name:dgoR Synonyms:yidW Ordered Locus Names:b4479, JW5627 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050621 | 1 – 229 | Galactonate operon transcriptional repressorAdd BLAST | 229 |
Proteomic databases
jPOSTi | P31460 |
PaxDbi | P31460 |
PRIDEi | P31460 |
Interactioni
GO - Molecular functioni
- identical protein binding Source: EcoCyc
Protein-protein interaction databases
BioGRIDi | 4263373, 13 interactors 853514, 1 interactor |
DIPi | DIP-9435N |
STRINGi | 511145.b4479 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 71 | HTH gntR-typePROSITE-ProRule annotationAdd BLAST | 71 |
Phylogenomic databases
eggNOGi | COG2186, Bacteria |
HOGENOMi | CLU_017584_9_4_6 |
InParanoidi | P31460 |
PhylomeDBi | P31460 |
Family and domain databases
CDDi | cd07377, WHTH_GntR, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 1.20.120.530, 1 hit |
InterProi | View protein in InterPro IPR011711, GntR_C IPR008920, TF_FadR/GntR_C IPR000524, Tscrpt_reg_HTH_GntR IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF07729, FCD, 1 hit PF00392, GntR, 1 hit |
PRINTSi | PR00035, HTHGNTR |
SMARTi | View protein in SMART SM00895, FCD, 1 hit SM00345, HTH_GNTR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF48008, SSF48008, 1 hit |
PROSITEi | View protein in PROSITE PS50949, HTH_GNTR, 1 hit |
i Sequence
Sequence statusi: Complete.
P31460-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTLNKTDRIV ITLGKQIVHG KYVPGSPLPA EAELCEEFAT SRNIIREVFR
60 70 80 90 100
SLMAKRLIEM KRYRGAFVAP RNQWNYLDTD VLQWVLENDY DPRLISAMSE
110 120 130 140 150
VRNLVEPAIA RWAAERATSS DLAQIESALN EMIANNQDRE AFNEADIRYH
160 170 180 190 200
EAVLQSVHNP VLQQLSIAIS SLQRAVFERT WMGDEANMPQ TLQEHKALFD
210 220
AIRHQDGDAA EQAALTMIAS STRRLKEIT
Sequence cautioni
The sequence AAA62046 differs from that shown. Reason: Frameshift.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 111 – 112 | RW → VA in AAA62046 (PubMed:7686882).Curated | 2 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L10328 Genomic DNA Translation: AAA62046.1 Frameshift. U00096 Genomic DNA Translation: AAT48199.1 AP009048 Genomic DNA Translation: BAE77599.1 |
RefSeqi | WP_000174305.1, NZ_STEB01000015.1 YP_026239.1, NC_000913.3 |
Genome annotation databases
EnsemblBacteriai | AAT48199; AAT48199; b4479 BAE77599; BAE77599; BAE77599 |
GeneIDi | 2847767 49582329 |
KEGGi | ecj:JW5627 eco:b4479 |
PATRICi | fig|1411691.4.peg.3008 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L10328 Genomic DNA Translation: AAA62046.1 Frameshift. U00096 Genomic DNA Translation: AAT48199.1 AP009048 Genomic DNA Translation: BAE77599.1 |
RefSeqi | WP_000174305.1, NZ_STEB01000015.1 YP_026239.1, NC_000913.3 |
3D structure databases
SMRi | P31460 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4263373, 13 interactors 853514, 1 interactor |
DIPi | DIP-9435N |
STRINGi | 511145.b4479 |
Proteomic databases
jPOSTi | P31460 |
PaxDbi | P31460 |
PRIDEi | P31460 |
Genome annotation databases
EnsemblBacteriai | AAT48199; AAT48199; b4479 BAE77599; BAE77599; BAE77599 |
GeneIDi | 2847767 49582329 |
KEGGi | ecj:JW5627 eco:b4479 |
PATRICi | fig|1411691.4.peg.3008 |
Organism-specific databases
EchoBASEi | EB1669 |
Phylogenomic databases
eggNOGi | COG2186, Bacteria |
HOGENOMi | CLU_017584_9_4_6 |
InParanoidi | P31460 |
PhylomeDBi | P31460 |
Enzyme and pathway databases
BioCyci | EcoCyc:G7790-MONOMER |
Miscellaneous databases
PROi | PR:P31460 |
Family and domain databases
CDDi | cd07377, WHTH_GntR, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 1.20.120.530, 1 hit |
InterProi | View protein in InterPro IPR011711, GntR_C IPR008920, TF_FadR/GntR_C IPR000524, Tscrpt_reg_HTH_GntR IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF07729, FCD, 1 hit PF00392, GntR, 1 hit |
PRINTSi | PR00035, HTHGNTR |
SMARTi | View protein in SMART SM00895, FCD, 1 hit SM00345, HTH_GNTR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF48008, SSF48008, 1 hit |
PROSITEi | View protein in PROSITE PS50949, HTH_GNTR, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DGOR_ECOLI | |
Accessioni | P31460Primary (citable) accession number: P31460 Secondary accession number(s): O32529 Q6BF15 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1993 |
Last sequence update: | October 11, 2004 | |
Last modified: | December 2, 2020 | |
This is version 151 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |