glvG

Functionⁱ

Miscellaneous

The GlvG polypeptide of 212 residues cross-reacts with anti-body prepared against the full-length 6-phospho-alpha-D-glucosidase (MalH) from Fusobacterium mortiferum. This operon may be cryptic in wild-type K12 strains (Probable).1 Publication

Caution

Could be the product of a pseudogene. Lacks the C-terminal half of the catalytic domain found in other members of this family. This truncated polypeptide does not display phospho-alpha- or phospho-beta-glucosidase activity (PubMed:9209025).1 Publication

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Metal bindingⁱ	169	ManganeseBy similarity		1
Metal bindingⁱ	200	ManganeseBy similarity		1

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Nucleotide bindingⁱ	4 – 70	NADBy similarityAdd BLAST		67

GO - Molecular functionⁱ

hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro
metal ion binding Source: UniProtKB-KW
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

carbohydrate metabolic process Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Manganese, Metal-binding, NAD

Ligand

Manganese, Metal-binding, NAD

Enzyme and pathway databases

BioCycⁱ	EcoCyc:EG11708-MONOMER

BioCycⁱ

EcoCyc:EG11708-MONOMER

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GH4 Glycoside Hydrolase Family 4

CAZyⁱ

GH4 Glycoside Hydrolase Family 4

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Putative inactive 6-phospho-alpha-glucosidase
Gene namesⁱ	Name:glvG1 Publication Ordered Locus Names:b4556 ORF Names:b3681
Organismⁱ	Escherichia coli (strain K12)
Taxonomic identifierⁱ	83333 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Proteomesⁱ	UP000000625 Componentⁱ: Chromosome

Organism-specific databases

EcoGeneⁱ	EG11708 glvG

EcoGeneⁱ

EG11708 glvG

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000169860	1 – 212	Putative inactive 6-phospho-alpha-glucosidaseAdd BLAST		212

Proteomic databases

PRIDEⁱ	P31450

PRIDEⁱ

P31450

Interactionⁱ

Protein-protein interaction databases

Database of interacting proteins More...DIPⁱ	DIP-9813N
IntActⁱ	P31450, 7 interactors

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P31450
SMRⁱ	P31450
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the glycosyl hydrolase 4 family.Curated

Phylogenomic databases

HOGENOMⁱ	HOG000202516
PhylomeDBⁱ	P31450

Family and domain databases

Gene3Dⁱ	3.90.110.10, 1 hit
InterProⁱ	View protein in InterPro IPR019802 GlycHydrolase_4_CS IPR001088 Glyco_hydro_4 IPR015955 Lactate_DH/Glyco_Ohase_4_C IPR036291 NAD(P)-bd_dom_sf
PANTHERⁱ	PTHR32092 PTHR32092, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02056 Glyco_hydro_4, 1 hit
PRINTSⁱ	PR00732 GLHYDRLASE4
SUPFAMⁱ	SSF51735 SSF51735, 1 hit SSF56327 SSF56327, 1 hit
PROSITEⁱ	View protein in PROSITE PS01324 GLYCOSYL_HYDROL_F4, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P31450-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTKFSVVVAG GGSTFTPGIV LMLLANQDRF PLRALKFYDN DGARQEVIAE 
        60         70         80         90        100
ACKVILKEKA PDIAFSYTTD PEVAFSDVDF VMAHIRVGKY PMRELDEKIP 
       110        120        130        140        150
LRHGVVGQET CGPGGIAYGM RSIGGVLELV DYMEKYSPNA WMLNYSNPAA 
       160        170        180        190        200
IVAEATRRLR PNAKILNICD MPIGIESRMA QIVGLQDRKQ MRVRYYGLNH 
       210 
WWSAISRSFR KG

Length:212

Mass (Da):23,724

Last modified:July 1, 1993 - v1

Checksum:ⁱ43FAD27B6D83FD1C

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L10328 Genomic DNA Translation: AAA62033.1 U00096 Genomic DNA No translation available.
PIRⁱ	B65170

Genome annotation databases

PATRICⁱ	fig\|83333.103.peg.4616

PATRICⁱ

fig|83333.103.peg.4616

Protein	Similar proteins		Species	Score	Length	Source
P31450	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases		uncultured gamma proteobacterium HF0770_33G18		212	UniRef100_P31450
Inactive 6-phospho-alpha-glucosidase		Escherichia coli M8		212
6-phospho-alpha-glucosidase		ECOLX		212
Family 4 glycosyl hydrolase		Escherichia coli MS 145-7		212
Family 4 glycosyl hydrolase		Escherichia coli MS 117-3		212
+31

Protein	Similar proteins		Species	Score	Length	Source
P31450	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases		uncultured gamma proteobacterium HF0770_33G18		212	UniRef90_P31450
Inactive 6-phospho-alpha-glucosidase		Escherichia coli M8		212
6-phospho-alpha-glucosidase		ECOLX		212
Family 4 glycosyl hydrolase		Escherichia coli MS 145-7		212
Family 4 glycosyl hydrolase		Escherichia coli MS 117-3		212
+87

Protein	Similar proteins		Species	Score	Length	Source
P31450	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases		uncultured gamma proteobacterium HF0770_33G18		212	UniRef50_P31450
Inactive 6-phospho-alpha-glucosidase		Escherichia coli M8		212
6-phospho-alpha-glucosidase		ECOLX		212
Family 4 glycosyl hydrolase		Escherichia coli MS 145-7		212
Family 4 glycosyl hydrolase		Escherichia coli MS 117-3		212
+95

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L10328 Genomic DNA Translation: AAA62033.1 U00096 Genomic DNA No translation available.
PIRⁱ	B65170

3D structure databases

ProteinModelPortalⁱ	P31450
SMRⁱ	P31450
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

DIPⁱ	DIP-9813N
IntActⁱ	P31450, 7 interactors

Protein family/group databases

CAZyⁱ	GH4 Glycoside Hydrolase Family 4

CAZyⁱ

GH4 Glycoside Hydrolase Family 4

Proteomic databases

PRIDEⁱ	P31450

PRIDEⁱ

P31450

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

PATRICⁱ	fig\|83333.103.peg.4616

PATRICⁱ

fig|83333.103.peg.4616

Organism-specific databases

EchoBASEⁱ	EB1659
EcoGeneⁱ	EG11708 glvG

Phylogenomic databases

HOGENOMⁱ	HOG000202516
PhylomeDBⁱ	P31450

Enzyme and pathway databases

BioCycⁱ	EcoCyc:EG11708-MONOMER

BioCycⁱ

EcoCyc:EG11708-MONOMER

Family and domain databases

Gene3Dⁱ	3.90.110.10, 1 hit
InterProⁱ	View protein in InterPro IPR019802 GlycHydrolase_4_CS IPR001088 Glyco_hydro_4 IPR015955 Lactate_DH/Glyco_Ohase_4_C IPR036291 NAD(P)-bd_dom_sf
PANTHERⁱ	PTHR32092 PTHR32092, 1 hit
Pfamⁱ	View protein in Pfam PF02056 Glyco_hydro_4, 1 hit
PRINTSⁱ	PR00732 GLHYDRLASE4
SUPFAMⁱ	SSF51735 SSF51735, 1 hit SSF56327 SSF56327, 1 hit
PROSITEⁱ	View protein in PROSITE PS01324 GLYCOSYL_HYDROL_F4, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	GLVG_ECOLI
Accessionⁱ	P31450Primary (citable) accession number: P31450
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
	Last sequence update:	July 1, 1993
	Last modified:	November 7, 2018
	This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries
Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P31450 (GLVG_ECOLI)

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Putative inactive 6-phospho-alpha-glucosidase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Caution

Sites

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ