We will be switching to the new UniProt website on Tuesday, June 28. Please explore and share your feedback.
Take me to UniProt BETA
UniProtKB - P31448 (YIDK_ECOLI)
Protein
Uncharacterized symporter YidK
Gene
yidK
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- glucose:sodium symporter activity Source: GO_Central
Keywordsi
Biological process | Ion transport, Sodium transport, Symport, Transport |
Ligand | Sodium |
Enzyme and pathway databases
BioCyci | EcoCyc:YIDK-MONOMER |
Protein family/group databases
TCDBi | 2.A.21.3.21, the solute:sodium symporter (sss) family |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized symporter YidK |
Gene namesi | Name:yidK Ordered Locus Names:b3679, JW3655 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 3 | CytoplasmicSequence analysis | 3 | |
Transmembranei | 4 – 24 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 25 – 74 | PeriplasmicSequence analysisAdd BLAST | 50 | |
Transmembranei | 75 – 95 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 96 – 118 | CytoplasmicSequence analysisAdd BLAST | 23 | |
Transmembranei | 119 – 139 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 140 – 162 | PeriplasmicSequence analysisAdd BLAST | 23 | |
Transmembranei | 163 – 183 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 184 – 191 | CytoplasmicSequence analysis | 8 | |
Transmembranei | 192 – 212 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 213 – 240 | PeriplasmicSequence analysisAdd BLAST | 28 | |
Transmembranei | 241 – 261 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 262 – 283 | CytoplasmicSequence analysisAdd BLAST | 22 | |
Transmembranei | 284 – 304 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 305 – 324 | PeriplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 325 – 345 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 346 – 380 | CytoplasmicSequence analysisAdd BLAST | 35 | |
Transmembranei | 381 – 401 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 402 – 415 | PeriplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 416 – 436 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 437 | CytoplasmicSequence analysis | 1 | |
Transmembranei | 438 – 458 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 459 – 460 | PeriplasmicSequence analysis | 2 | |
Transmembranei | 461 – 481 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 482 – 505 | CytoplasmicSequence analysisAdd BLAST | 24 | |
Transmembranei | 506 – 526 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 527 – 532 | PeriplasmicSequence analysis | 6 | |
Transmembranei | 533 – 553 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 554 – 571 | CytoplasmicSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000105406 | 1 – 571 | Uncharacterized symporter YidKAdd BLAST | 571 |
Proteomic databases
PaxDbi | P31448 |
PRIDEi | P31448 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261452, 162 interactors |
DIPi | DIP-12450N |
IntActi | P31448, 5 interactors |
STRINGi | 511145.b3679 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG4146, Bacteria |
HOGENOMi | CLU_018808_9_3_6 |
InParanoidi | P31448 |
OMAi | MFFVVMP |
PhylomeDBi | P31448 |
Family and domain databases
Gene3Di | 1.20.1730.10, 1 hit |
InterProi | View protein in InterPro IPR038377, Na/Glc_symporter_sf IPR001734, Na/solute_symporter IPR018212, Na/solute_symporter_CS |
Pfami | View protein in Pfam PF00474, SSF, 1 hit |
TIGRFAMsi | TIGR00813, sss, 1 hit |
PROSITEi | View protein in PROSITE PS00456, NA_SOLUT_SYMP_1, 1 hit PS50283, NA_SOLUT_SYMP_3, 1 hit |
i Sequence
Sequence statusi: Complete.
P31448-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNSLQILSFV GFTLLVAVIT WWKVRKTDTG SQQGYFLAGR SLKAPVIAAS
60 70 80 90 100
LMLTNLSTEQ LVGLSGQAYK SGMSVMGWEV TSAVTLIFLA LIFLPRYLKR
110 120 130 140 150
GIATIPDFLE ERYDKTTRII IDFCFLIATG VCFLPIVLYS GALALNSLFH
160 170 180 190 200
VGESLQISHG AAIWLLVILL GLAGILYAVI GGLRAMAVAD SINGIGLVIG
210 220 230 240 250
GLMVPVFGLI AMGKGSFMQG IEQLTTVHAE KLNSIGGPTD PLPIGAAFTG
260 270 280 290 300
LILVNTFYWC TNQGIVQRTL ASKSLAEGQK GALLTAVLKM LDPLVLVLPG
310 320 330 340 350
LIAFHLYQDL PKADMAYPTL VNNVLPVPMV GFFGAVLFGA VISTFNGFLN
360 370 380 390 400
SASTLFSMGI YRRIINQNAE PQQLVTVGRK FGFFIAIVSV LVAPWIANAP
410 420 430 440 450
QGLYSWMKQL NGIYNVPLVT IIIMGFFFPR IPALAAKVAM GIGIISYITI
460 470 480 490 500
NYLVKFDFHF LYVLACTFCI NVVVMLVIGF IKPRATPFTF KDAFAVDMKP
510 520 530 540 550
WKNVKIASIG ILFAMIGVYA GLAEFGGYGT RWLAMISYFI AAVVIVYLIF
560 570
DSWRHRHDPA VTFTPDGKDS L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L10328 Genomic DNA Translation: AAA62031.1 U00096 Genomic DNA Translation: AAC76702.1 AP009048 Genomic DNA Translation: BAE77614.1 |
PIRi | H65169 |
RefSeqi | NP_418135.1, NC_000913.3 WP_001087145.1, NZ_SSZK01000035.1 |
Genome annotation databases
EnsemblBacteriai | AAC76702; AAC76702; b3679 BAE77614; BAE77614; BAE77614 |
GeneIDi | 948185 |
KEGGi | ecj:JW3655 eco:b3679 |
PATRICi | fig|1411691.4.peg.3025 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L10328 Genomic DNA Translation: AAA62031.1 U00096 Genomic DNA Translation: AAC76702.1 AP009048 Genomic DNA Translation: BAE77614.1 |
PIRi | H65169 |
RefSeqi | NP_418135.1, NC_000913.3 WP_001087145.1, NZ_SSZK01000035.1 |
3D structure databases
AlphaFoldDBi | P31448 |
SMRi | P31448 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4261452, 162 interactors |
DIPi | DIP-12450N |
IntActi | P31448, 5 interactors |
STRINGi | 511145.b3679 |
Protein family/group databases
TCDBi | 2.A.21.3.21, the solute:sodium symporter (sss) family |
Proteomic databases
PaxDbi | P31448 |
PRIDEi | P31448 |
Genome annotation databases
EnsemblBacteriai | AAC76702; AAC76702; b3679 BAE77614; BAE77614; BAE77614 |
GeneIDi | 948185 |
KEGGi | ecj:JW3655 eco:b3679 |
PATRICi | fig|1411691.4.peg.3025 |
Organism-specific databases
EchoBASEi | EB1657 |
Phylogenomic databases
eggNOGi | COG4146, Bacteria |
HOGENOMi | CLU_018808_9_3_6 |
InParanoidi | P31448 |
OMAi | MFFVVMP |
PhylomeDBi | P31448 |
Enzyme and pathway databases
BioCyci | EcoCyc:YIDK-MONOMER |
Miscellaneous databases
PROi | PR:P31448 |
Family and domain databases
Gene3Di | 1.20.1730.10, 1 hit |
InterProi | View protein in InterPro IPR038377, Na/Glc_symporter_sf IPR001734, Na/solute_symporter IPR018212, Na/solute_symporter_CS |
Pfami | View protein in Pfam PF00474, SSF, 1 hit |
TIGRFAMsi | TIGR00813, sss, 1 hit |
PROSITEi | View protein in PROSITE PS00456, NA_SOLUT_SYMP_1, 1 hit PS50283, NA_SOLUT_SYMP_3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YIDK_ECOLI | |
Accessioni | P31448Primary (citable) accession number: P31448 Secondary accession number(s): Q2M7Z2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1993 |
Last sequence update: | July 1, 1993 | |
Last modified: | May 25, 2022 | |
This is version 155 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families