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UniProtKB - P31437 (YICL_ECOLI)
Protein
Uncharacterized inner membrane transporter YicL
Gene
yicL
Organism
Escherichia coli (strain K12)
Status
Functioni
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11688-MONOMER |
Protein family/group databases
TCDBi | 2.A.7.3.12, the drug/metabolite transporter (dmt) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized inner membrane transporter YicL |
Gene namesi | Name:yicL Ordered Locus Names:b3660, JW3634 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 7 | PeriplasmicSequence analysis | 7 | |
Transmembranei | 8 – 28 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 29 – 45 | CytoplasmicSequence analysisAdd BLAST | 17 | |
Transmembranei | 46 – 66 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 67 – 71 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 72 – 92 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 93 – 99 | CytoplasmicSequence analysis | 7 | |
Transmembranei | 100 – 120 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 121 – 124 | PeriplasmicSequence analysis | 4 | |
Transmembranei | 125 – 145 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 146 – 151 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 152 – 172 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 173 – 184 | PeriplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 185 – 205 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 206 – 216 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 217 – 237 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 238 – 263 | PeriplasmicSequence analysisAdd BLAST | 26 | |
Transmembranei | 264 – 284 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 285 – 307 | CytoplasmicSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000108173 | 1 – 307 | Uncharacterized inner membrane transporter YicLAdd BLAST | 307 |
Proteomic databases
PaxDbi | P31437 |
PRIDEi | P31437 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4259627, 17 interactors |
STRINGi | 511145.b3660 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 145 | EamA 1Add BLAST | 130 | |
Domaini | 167 – 291 | EamA 2Add BLAST | 125 |
Sequence similaritiesi
Belongs to the EamA transporter family.Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0697, Bacteria |
HOGENOMi | CLU_033863_19_0_6 |
InParanoidi | P31437 |
PhylomeDBi | P31437 |
Family and domain databases
InterProi | View protein in InterPro IPR004779, CO/AA/NH_transpt IPR000620, EamA_dom |
Pfami | View protein in Pfam PF00892, EamA, 2 hits |
TIGRFAMsi | TIGR00950, 2A78, 1 hit |
i Sequence
Sequence statusi: Complete.
P31437-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGSTRKGMLN VLIAAVLWGS SGVCAQYIME QSQMSSQFLT MTRLIFAGLI
60 70 80 90 100
LLTLSFVHGD KIFSIINNHK DAISLLIFSV VGALTVQLTF LLTIEKSNAA
110 120 130 140 150
TATVLQFLSP TIIVAWFSLV RKSRPGILVF CAILTSLVGT FLLVTHGNPT
160 170 180 190 200
SLSISPAALF WGIASAFAAA FYTTYPSTLI ARYGTLPVVG WSMLIGGLIL
210 220 230 240 250
LPFYARQGTN FVVNGSLILA FFYLVVIGTS LTFSLYLKGA QLIGGPKASI
260 270 280 290 300
LSCAEPLSSA LLSLLLLGIT FTLPDWLGTL LILSSVILIS MDSRRRARKI
NRPARHK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L10328 Genomic DNA Translation: AAA62012.1 U00096 Genomic DNA Translation: AAC76683.1 AP009048 Genomic DNA Translation: BAE77634.1 |
PIRi | E65167 |
RefSeqi | NP_418116.1, NC_000913.3 WP_000535961.1, NZ_SSZK01000043.1 |
Genome annotation databases
EnsemblBacteriai | AAC76683; AAC76683; b3660 BAE77634; BAE77634; BAE77634 |
GeneIDi | 948176 |
KEGGi | ecj:JW3634 eco:b3660 |
PATRICi | fig|1411691.4.peg.3046 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L10328 Genomic DNA Translation: AAA62012.1 U00096 Genomic DNA Translation: AAC76683.1 AP009048 Genomic DNA Translation: BAE77634.1 |
PIRi | E65167 |
RefSeqi | NP_418116.1, NC_000913.3 WP_000535961.1, NZ_SSZK01000043.1 |
3D structure databases
SMRi | P31437 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4259627, 17 interactors |
STRINGi | 511145.b3660 |
Protein family/group databases
TCDBi | 2.A.7.3.12, the drug/metabolite transporter (dmt) superfamily |
Proteomic databases
PaxDbi | P31437 |
PRIDEi | P31437 |
Genome annotation databases
EnsemblBacteriai | AAC76683; AAC76683; b3660 BAE77634; BAE77634; BAE77634 |
GeneIDi | 948176 |
KEGGi | ecj:JW3634 eco:b3660 |
PATRICi | fig|1411691.4.peg.3046 |
Organism-specific databases
EchoBASEi | EB1639 |
Phylogenomic databases
eggNOGi | COG0697, Bacteria |
HOGENOMi | CLU_033863_19_0_6 |
InParanoidi | P31437 |
PhylomeDBi | P31437 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11688-MONOMER |
Miscellaneous databases
PROi | PR:P31437 |
Family and domain databases
InterProi | View protein in InterPro IPR004779, CO/AA/NH_transpt IPR000620, EamA_dom |
Pfami | View protein in Pfam PF00892, EamA, 2 hits |
TIGRFAMsi | TIGR00950, 2A78, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YICL_ECOLI | |
Accessioni | P31437Primary (citable) accession number: P31437 Secondary accession number(s): Q2M7X2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1993 |
Last sequence update: | July 1, 1993 | |
Last modified: | February 23, 2022 | |
This is version 142 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families