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Entry version 152 (17 Jun 2020)
Sequence version 2 (21 Nov 2003)
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Protein

Adenine phosphoribosyltransferase 1, chloroplastic

Gene

APT1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Contributes primarily to the recycling of adenine into adenylate nucleotides, but is also involved in the inactivation of cytokinins by phosphoribosylation. Catalyzes the conversion of cytokinins from free bases (active form) to the corresponding nucleotides (inactive form).4 Publications

Miscellaneous

Plants with reduced activity of APT1 and increased levels of cellular adenine show enhanced stress tolerance and improve growth, leading to increases in plant biomass.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=1 µM for adenine (at pH 7.4 and 37 degrees Celsius)1 Publication
  2. KM=1800 µM for zeatin (at pH 7.4 and 37 degrees Celsius)1 Publication
  3. KM=2500 µM for isopentenyladenine (at pH 7.4 and 37 degrees Celsius)1 Publication
  4. KM=2400 µM for benzyladenine (at pH 7.4 and 37 degrees Celsius)1 Publication
  1. Vmax=9.6 µmol/min/mg enzyme with adenine as substrate (at pH 7.4 and 37 degrees Celsius)1 Publication
  2. Vmax=10 µmol/min/mg enzyme with zeatin as substrate (at pH 7.4 and 37 degrees Celsius)1 Publication
  3. Vmax=6.7 µmol/min/mg enzyme with isopentenyladenine as substrate (at pH 7.4 and 37 degrees Celsius)1 Publication
  4. Vmax=1.5 µmol/min/mg enzyme with benzyladenine as substrate (at pH 7.4 and 37 degrees Celsius)1 Publication

pH dependencei

Optimum pH is 8.8.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: AMP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes AMP from adenine.
Proteins known to be involved in this subpathway in this organism are:
  1. Adenine phosphoribosyltransferase (APT1), Adenine phosphoribosyltransferase, Adenine phosphoribosyltransferase (AXX17_At5g10840), Adenine phosphoribosyltransferase 3 (APT3), Adenine phosphoribosyltransferase 1, chloroplastic (APT1), Adenine phosphoribosyltransferase (AXX17_At4g14010), Adenine phosphoribosyltransferase (AXX17_At4g26200), Adenine phosphoribosyltransferase 4 (APT4), Adenine phosphoribosyltransferase 2 (APT2), Adenine phosphoribosyltransferase (AXX17_At1g74900), Adenine phosphoribosyltransferase (AXX17_At1g27890), Adenine phosphoribosyltransferase (C24_LOCUS6937), Adenine phosphoribosyltransferase (AXX17_At1g27890), Adenine phosphoribosyltransferase (AXX17_At4g14010), Adenine phosphoribosyltransferase 5 (APT5), Adenine phosphoribosyltransferase (APT2), Adenine phosphoribosyltransferase (APT5)
This subpathway is part of the pathway AMP biosynthesis via salvage pathway, which is itself part of Purine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes AMP from adenine, the pathway AMP biosynthesis via salvage pathway and in Purine metabolism.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • adenine phosphoribosyltransferase activity Source: UniProtKB

GO - Biological processi

  • adenine salvage Source: InterPro
  • AMP salvage Source: UniProtKB
  • cytokinin metabolic process Source: UniProtKB
  • purine ribonucleoside salvage Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processPurine salvage

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:AT1G27450-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00588;UER00646

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Adenine phosphoribosyltransferase 1, chloroplastic (EC:2.4.2.7)
Short name:
APRT 1
Short name:
AtAPT1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:APT1
Synonyms:APT
Ordered Locus Names:At1g27450
ORF Names:F17L21.24
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G27450

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Cytoplasm, Plastid

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Male sterility due to pollen abortion after meiosis. Accumulation of free bases of cytokinins and enhanced resistance to exogenous cytokinins.2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi85P → T in apt1-5; loss of activity. 1 Publication1
Mutagenesisi99L → F in apt1-6; reduces activity 10-fold. 1 Publication1
Mutagenesisi149R → K in apt1-7; loss of activity and male sterility. 1 Publication1
Mutagenesisi168G → E in apt1-4; reduces activity 3-fold. 1 Publication1
Mutagenesisi195G → D in apt1-8; loss of activity and male sterility. 1 Publication1
Mutagenesisi196G → R in apt1-9; loss of activity and male sterility. 1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 52ChloroplastSequence analysisAdd BLAST52
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000014951453 – 243Adenine phosphoribosyltransferase 1, chloroplasticAdd BLAST191
Isoform 2 (identifier: P31166-2)
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Isoform 2 (identifier: P31166-2)
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P31166

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
244487 [P31166-1]

PTM databases

MetOSite database of methionine sulfoxide sites

More...
MetOSitei
P31166

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P31166, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P31166, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
24871, 3 interactors

Protein interaction database and analysis system

More...
IntActi
P31166, 4 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P31166

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P31166

KEGG Orthology (KO)

More...
KOi
K00759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P31166

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06223, PRTases_typeI, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.2020, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00004, Aden_phosphoribosyltr, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005764, Ade_phspho_trans
IPR000836, PRibTrfase_dom
IPR029057, PRTase-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00156, Pribosyltran, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53271, SSF53271, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01090, apt, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00103, PUR_PYR_PR_TRANSFER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: P31166-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQTIIISPLV SHRLCLARAV PCNRLLNNHH RAPPSIRLSN HRSTTSLRLF
60 70 80 90 100
SSAAASRDSE MATEDVQDPR IAKIASSIRV IPDFPKPGIM FQDITTLLLD
110 120 130 140 150
TEAFKDTIAL FVDRYKDKGI SVVAGVEARG FIFGPPIALA IGAKFVPMRK
160 170 180 190 200
PKKLPGKVIS EEYSLEYGTD TIEMHVGAVE PGERAIIIDD LIATGGTLAA
210 220 230 240
AIRLLERVGV KIVECACVIE LPELKGKEKL GETSLFVLVK SAA
Length:243
Mass (Da):26,396
Last modified:November 21, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i92ABF089CA66C0FD
GO
Isoform 2 (identifier: P31166-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-60: Missing.

Show »
Length:183
Mass (Da):19,739
Checksum:iA9D5FDF7FD130254
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4HSX1F4HSX1_ARATH
Adenine phosphoribosyltransferase
APT1 ATAPT1, At1g27450, F17L21.24, F17L21_24
284Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF99737 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0090021 – 60Missing in isoform 2. 2 PublicationsAdd BLAST60

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X58640 mRNA Translation: CAA41497.1
L19637 Genomic DNA Translation: AAA20677.1
AC004557 Genomic DNA Translation: AAF99737.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE30831.1
CP002684 Genomic DNA Translation: AEE30832.1
CP002684 Genomic DNA Translation: ANM60751.1
AF325045 mRNA Translation: AAG40397.1
AY128377 mRNA Translation: AAM91580.1
BT000370 mRNA Translation: AAN15689.1
AY084300 mRNA Translation: AAM60891.1

Protein sequence database of the Protein Information Resource

More...
PIRi
G86399
S20867

NCBI Reference Sequences

More...
RefSeqi
NP_001323015.1, NM_001332762.1 [P31166-2]
NP_564284.1, NM_102509.4 [P31166-1]
NP_849714.1, NM_179383.3 [P31166-2]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G27450.1; AT1G27450.1; AT1G27450 [P31166-1]
AT1G27450.2; AT1G27450.2; AT1G27450 [P31166-2]
AT1G27450.4; AT1G27450.4; AT1G27450 [P31166-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
839636

Gramene; a comparative resource for plants

More...
Gramenei
AT1G27450.1; AT1G27450.1; AT1G27450 [P31166-1]
AT1G27450.2; AT1G27450.2; AT1G27450 [P31166-2]
AT1G27450.4; AT1G27450.4; AT1G27450 [P31166-2]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G27450

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X58640 mRNA Translation: CAA41497.1
L19637 Genomic DNA Translation: AAA20677.1
AC004557 Genomic DNA Translation: AAF99737.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE30831.1
CP002684 Genomic DNA Translation: AEE30832.1
CP002684 Genomic DNA Translation: ANM60751.1
AF325045 mRNA Translation: AAG40397.1
AY128377 mRNA Translation: AAM91580.1
BT000370 mRNA Translation: AAN15689.1
AY084300 mRNA Translation: AAM60891.1
PIRiG86399
S20867
RefSeqiNP_001323015.1, NM_001332762.1 [P31166-2]
NP_564284.1, NM_102509.4 [P31166-1]
NP_849714.1, NM_179383.3 [P31166-2]

3D structure databases

SMRiP31166
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi24871, 3 interactors
IntActiP31166, 4 interactors

PTM databases

MetOSiteiP31166

Proteomic databases

PRIDEiP31166
ProteomicsDBi244487 [P31166-1]

Genome annotation databases

EnsemblPlantsiAT1G27450.1; AT1G27450.1; AT1G27450 [P31166-1]
AT1G27450.2; AT1G27450.2; AT1G27450 [P31166-2]
AT1G27450.4; AT1G27450.4; AT1G27450 [P31166-2]
GeneIDi839636
GrameneiAT1G27450.1; AT1G27450.1; AT1G27450 [P31166-1]
AT1G27450.2; AT1G27450.2; AT1G27450 [P31166-2]
AT1G27450.4; AT1G27450.4; AT1G27450 [P31166-2]
KEGGiath:AT1G27450

Organism-specific databases

AraportiAT1G27450

Phylogenomic databases

InParanoidiP31166
KOiK00759
PhylomeDBiP31166

Enzyme and pathway databases

UniPathwayiUPA00588;UER00646
BioCyciMetaCyc:AT1G27450-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P31166

Gene expression databases

ExpressionAtlasiP31166, baseline and differential
GenevisibleiP31166, AT

Family and domain databases

CDDicd06223, PRTases_typeI, 1 hit
Gene3Di3.40.50.2020, 1 hit
HAMAPiMF_00004, Aden_phosphoribosyltr, 1 hit
InterProiView protein in InterPro
IPR005764, Ade_phspho_trans
IPR000836, PRibTrfase_dom
IPR029057, PRTase-like
PfamiView protein in Pfam
PF00156, Pribosyltran, 1 hit
SUPFAMiSSF53271, SSF53271, 1 hit
TIGRFAMsiTIGR01090, apt, 1 hit
PROSITEiView protein in PROSITE
PS00103, PUR_PYR_PR_TRANSFER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAPT1_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P31166
Secondary accession number(s): Q8LGF6, Q9FZJ0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 21, 2003
Last modified: June 17, 2020
This is version 152 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families
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