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UniProtKB - P31112 (HEPS1_BACSU)
Protein
Heptaprenyl diphosphate synthase component 1
Gene
hepS
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7).
1 PublicationCatalytic activityi
- (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + 4 diphosphateEC:2.5.1.30
GO - Molecular functioni
- heptaprenyl diphosphate synthase activity Source: UniProtKB-EC
- transferase activity, transferring alkyl or aryl (other than methyl) groups Source: UniProtKB
GO - Biological processi
- isoprenoid biosynthetic process Source: UniProtKB-KW
- menaquinone biosynthetic process Source: UniProtKB
- sporulation resulting in formation of a cellular spore Source: UniProtKB-KW
Keywordsi
Molecular function | Transferase |
Biological process | Isoprene biosynthesis, Sporulation |
Enzyme and pathway databases
BioCyci | BSUB:BSU22760-MONOMER |
BRENDAi | 2.5.1.30, 658 |
SABIO-RKi | P31112 |
Names & Taxonomyi
Protein namesi | Recommended name: Heptaprenyl diphosphate synthase component 1 (EC:2.5.1.30)Short name: HepPP synthase subunit 1 Alternative name(s): Spore germination protein C1 |
Gene namesi | Name:hepS Synonyms:gerC1, gerCA, hepA Ordered Locus Names:BSU22760 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000124002 | 1 – 251 | Heptaprenyl diphosphate synthase component 1Add BLAST | 251 |
Proteomic databases
jPOSTi | P31112 |
PaxDbi | P31112 |
Interactioni
Subunit structurei
Heterodimer of component I and II.
Protein-protein interaction databases
STRINGi | 224308.BSU22760 |
Family & Domainsi
Phylogenomic databases
eggNOGi | COG0142, Bacteria |
OMAi | CDIYGGY |
PhylomeDBi | P31112 |
Family and domain databases
InterProi | View protein in InterPro IPR009920, HEPPP_synth_su1 |
Pfami | View protein in Pfam PF07307, HEPPP_synt_1, 1 hit |
i Sequence
Sequence statusi: Complete.
P31112-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQDIYGTLAN LNTKLKQKLS HPYLAKHISA PKIDEDKLLL FHALFEEADI
60 70 80 90 100
KNNDRENYIV TAMLVQSALD THDEVTTARV IKRDENKNRQ LTVLAGDYFS
110 120 130 140 150
GLYYSLLSEM KDIYMIRTLA TAIKEINEHK IRLYDRSFKD ENDFFESVGI
160 170 180 190 200
VESALFHRVA EHFNLPRWKK LSSDFFVFKR LMNGNDAFLD VIGSFIQLGK
210 220 230 240 250
TKEEILEDCF KKAKNSIESL LPLNSPIQNI LINRLKTISQ DQTYHQKVEE
G
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M80245 Genomic DNA Translation: AAA20854.1 AL009126 Genomic DNA Translation: CAB14192.1 |
PIRi | C69630 |
RefSeqi | NP_390157.1, NC_000964.3 WP_004398550.1, NZ_JNCM01000036.1 |
Genome annotation databases
EnsemblBacteriai | CAB14192; CAB14192; BSU_22760 |
GeneIDi | 938998 |
KEGGi | bsu:BSU22760 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M80245 Genomic DNA Translation: AAA20854.1 AL009126 Genomic DNA Translation: CAB14192.1 |
PIRi | C69630 |
RefSeqi | NP_390157.1, NC_000964.3 WP_004398550.1, NZ_JNCM01000036.1 |
3D structure databases
AlphaFoldDBi | P31112 |
SMRi | P31112 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 224308.BSU22760 |
Proteomic databases
jPOSTi | P31112 |
PaxDbi | P31112 |
Protocols and materials databases
DNASUi | 938998 |
Genome annotation databases
EnsemblBacteriai | CAB14192; CAB14192; BSU_22760 |
GeneIDi | 938998 |
KEGGi | bsu:BSU22760 |
Phylogenomic databases
eggNOGi | COG0142, Bacteria |
OMAi | CDIYGGY |
PhylomeDBi | P31112 |
Enzyme and pathway databases
BioCyci | BSUB:BSU22760-MONOMER |
BRENDAi | 2.5.1.30, 658 |
SABIO-RKi | P31112 |
Family and domain databases
InterProi | View protein in InterPro IPR009920, HEPPP_synth_su1 |
Pfami | View protein in Pfam PF07307, HEPPP_synt_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | HEPS1_BACSU | |
Accessioni | P31112Primary (citable) accession number: P31112 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1993 |
Last sequence update: | July 1, 1993 | |
Last modified: | May 25, 2022 | |
This is version 107 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |