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Entry version 137 (02 Dec 2020)
Sequence version 1 (01 Jul 1993)
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Protein

UPF0394 inner membrane protein YedE

Gene

yedE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
EcoCyc:EG11660-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
9.B.102.1.1, the yede/yeee (yede/yeee) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
UPF0394 inner membrane protein YedE
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yedE
Ordered Locus Names:b1929, JW1914
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 13CytoplasmicSequence analysisAdd BLAST13
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei14 – 34HelicalSequence analysisAdd BLAST21
Topological domaini35 – 78PeriplasmicSequence analysisAdd BLAST44
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Topological domaini100 – 111CytoplasmicSequence analysisAdd BLAST12
Transmembranei112 – 132HelicalSequence analysisAdd BLAST21
Topological domaini133PeriplasmicSequence analysis1
Transmembranei134 – 154HelicalSequence analysisAdd BLAST21
Topological domaini155 – 198CytoplasmicSequence analysisAdd BLAST44
Transmembranei199 – 219HelicalSequence analysisAdd BLAST21
Topological domaini220 – 259PeriplasmicSequence analysisAdd BLAST40
Transmembranei260 – 280HelicalSequence analysisAdd BLAST21
Topological domaini281 – 283CytoplasmicSequence analysis3
Transmembranei284 – 304HelicalSequence analysisAdd BLAST21
Topological domaini305 – 363PeriplasmicSequence analysisAdd BLAST59
Transmembranei364 – 384HelicalSequence analysisAdd BLAST21
Topological domaini385 – 401CytoplasmicSequence analysisAdd BLAST17

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001690901 – 401UPF0394 inner membrane protein YedEAdd BLAST401

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P31064

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P31064

PRoteomics IDEntifications database

More...
PRIDEi
P31064

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
4261058, 171 interactors

Database of interacting proteins

More...
DIPi
DIP-11839N

Protein interaction database and analysis system

More...
IntActi
P31064, 1 interactor

STRING: functional protein association networks

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STRINGi
511145.b1929

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P31064

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPF0394 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
COG2391, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_041737_0_0_6

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P31064

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR007272, Sulf_transp

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04143, Sulf_transp, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P31064-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSWQQFKHAW LIKFWAPIPA VIAAGILSTY YFGITGTFWA VTGEFTRWGG
60 70 80 90 100
QLLQLFGVHA EEWGYFKIIH LEGSPLTRID GMMILGMFGG CFAAALWANN
110 120 130 140 150
VKLRMPRSRI RIMQAIIGGI IAGFGARLAM GCNLAAFFTG IPQFSLHAWF
160 170 180 190 200
FAIATAIGSW FGARFTLLPI FRIPVKMQKV SAASPLTQKP DQARRRFRLG
210 220 230 240 250
MLVFFGMLGW ALLTAMNQPK LGLAMLFGVG FGLLIERAQI CFTSAFRDMW
260 270 280 290 300
ITGRTHMAKA IIIGMAVSAI GIFSYVQLGV EPKIMWAGPN AVIGGLLFGF
310 320 330 340 350
GIVLAGGCET GWMYRAVEGQ VHYWWVGLGN VIGSTILAYY WDDFAPALAT
360 370 380 390 400
DWDKINLLKT FGPMGGLLVT YLLLFAALML IIGWEKRFFR RAAPQTAKEI

A
Length:401
Mass (Da):44,429
Last modified:July 1, 1993 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE07554C206B367E4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
L13279 Genomic DNA Translation: AAA82577.1
U00096 Genomic DNA Translation: AAC74996.1
AP009048 Genomic DNA Translation: BAA15757.1

Protein sequence database of the Protein Information Resource

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PIRi
F64956

NCBI Reference Sequences

More...
RefSeqi
NP_416439.1, NC_000913.3
WP_000118897.1, NZ_SSUR01000001.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC74996; AAC74996; b1929
BAA15757; BAA15757; BAA15757

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
945192

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW1914
eco:b1929

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1411691.4.peg.320

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13279 Genomic DNA Translation: AAA82577.1
U00096 Genomic DNA Translation: AAC74996.1
AP009048 Genomic DNA Translation: BAA15757.1
PIRiF64956
RefSeqiNP_416439.1, NC_000913.3
WP_000118897.1, NZ_SSUR01000001.1

3D structure databases

SMRiP31064
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi4261058, 171 interactors
DIPiDIP-11839N
IntActiP31064, 1 interactor
STRINGi511145.b1929

Protein family/group databases

TCDBi9.B.102.1.1, the yede/yeee (yede/yeee) family

Proteomic databases

jPOSTiP31064
PaxDbiP31064
PRIDEiP31064

Genome annotation databases

EnsemblBacteriaiAAC74996; AAC74996; b1929
BAA15757; BAA15757; BAA15757
GeneIDi945192
KEGGiecj:JW1914
eco:b1929
PATRICifig|1411691.4.peg.320

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB1612

Phylogenomic databases

eggNOGiCOG2391, Bacteria
HOGENOMiCLU_041737_0_0_6
InParanoidiP31064

Enzyme and pathway databases

BioCyciEcoCyc:EG11660-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P31064

Family and domain databases

InterProiView protein in InterPro
IPR007272, Sulf_transp
PfamiView protein in Pfam
PF04143, Sulf_transp, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYEDE_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P31064
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: December 2, 2020
This is version 137 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  2. SIMILARITY comments
    Index of protein domains and families
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