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Protein

Lipocalin-1

Gene

LCN1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • chloride ion binding Source: CAFA
  • cysteine-type endopeptidase inhibitor activity Source: ProtInc
  • signaling receptor binding Source: UniProtKB
  • small molecule binding Source: InterPro
  • zinc ion binding Source: CAFA

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processSensory transduction, Taste, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-804914 Transport of fatty acids

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...
SwissLipidsi
SLP:000001525

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Lipocalin-1
Alternative name(s):
Tear lipocalin
Short name:
Tlc
Tear prealbumin
Short name:
TP
von Ebner gland protein
Short name:
VEG protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LCN1
Synonyms:VEGP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000160349.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:6525 LCN1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
151675 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P31025

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
3933

Open Targets

More...
OpenTargetsi
ENSG00000160349

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30308

Protein family/group databases

Allergome; a platform for allergen knowledge

More...
Allergomei
3990 Hom s TL

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
LCN1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
401346

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 182 PublicationsAdd BLAST18
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001797419 – 176Lipocalin-1Add BLAST158

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi79 ↔ 171

Keywords - PTMi

Disulfide bond

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P31025

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P31025

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P31025

PeptideAtlas

More...
PeptideAtlasi
P31025

PRoteomics IDEntifications database

More...
PRIDEi
P31025

ProteomicsDB human proteome resource

More...
ProteomicsDBi
54757

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P31025

2D gel databases

University College Dublin 2-DE Proteome Database

More...
UCD-2DPAGEi
P31025

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P31025

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P31025

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000160349 Expressed in 57 organ(s), highest expression level in tongue

CleanEx database of gene expression profiles

More...
CleanExi
HS_LCN1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P31025 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P31025 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer (By similarity). Binds to LMBR1L which may mediate its endocytosis.By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
110125, 23 interactors

Protein interaction database and analysis system

More...
IntActi
P31025, 6 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000263598

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1176
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P31025

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P31025

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P31025

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the calycin superfamily. Lipocalin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410J1KM Eukaryota
ENOG4111BH9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00440000033563

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231562

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG101411

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P31025

Identification of Orthologs from Complete Genome Data

More...
OMAi
SGKWYLK

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0PIH

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P31025

TreeFam database of animal gene trees

More...
TreeFami
TF338197

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.128.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012674 Calycin
IPR002345 Lipocalin
IPR000566 Lipocln_cytosolic_FA-bd_dom
IPR002450 von_Ebner_gland

The PANTHER Classification System

More...
PANTHERi
PTHR11430 PTHR11430, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00061 Lipocalin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01175 VNEBNERGLAND

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50814 SSF50814, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P31025-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKPLLLAVSL GLIAALQAHH LLASDEEIQD VSGTWYLKAM TVDREFPEMN
60 70 80 90 100
LESVTPMTLT TLEGGNLEAK VTMLISGRCQ EVKAVLEKTD EPGKYTADGG
110 120 130 140 150
KHVAYIIRSH VKDHYIFYCE GELHGKPVRG VKLVGRDPKN NLEALEDFEK
160 170
AAGARGLSTE SILIPRQSET CSPGSD
Length:176
Mass (Da):19,250
Last modified:July 1, 1993 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0DDBF124C8C78CB8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X62418 mRNA Translation: CAA44284.1
M90424 mRNA Translation: AAA61845.1
X67647 mRNA Translation: CAA47889.1
L14927 Genomic DNA Translation: AAA18633.1
AL161452 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW88156.1
BC065721 mRNA Translation: AAH65721.1
BC074925 mRNA Translation: AAH74925.1
BC074926 mRNA Translation: AAH74926.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6991.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A44029 LCHUL

NCBI Reference Sequences

More...
RefSeqi
NP_001239546.1, NM_001252617.1
NP_001239547.1, NM_001252618.1
NP_001239548.1, NM_001252619.1
NP_002288.1, NM_002297.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.530311

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000263598; ENSP00000263598; ENSG00000160349
ENST00000371781; ENSP00000360846; ENSG00000160349

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3933

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:3933

UCSC genome browser

More...
UCSCi
uc004cfz.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X62418 mRNA Translation: CAA44284.1
M90424 mRNA Translation: AAA61845.1
X67647 mRNA Translation: CAA47889.1
L14927 Genomic DNA Translation: AAA18633.1
AL161452 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW88156.1
BC065721 mRNA Translation: AAH65721.1
BC074925 mRNA Translation: AAH74925.1
BC074926 mRNA Translation: AAH74926.1
CCDSiCCDS6991.1
PIRiA44029 LCHUL
RefSeqiNP_001239546.1, NM_001252617.1
NP_001239547.1, NM_001252618.1
NP_001239548.1, NM_001252619.1
NP_002288.1, NM_002297.3
UniGeneiHs.530311

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XKIX-ray1.80A23-176[»]
3EYCX-ray2.60A/B/C/D23-176[»]
4QAFX-ray1.80A/B23-174[»]
5T43NMR-A19-176[»]
ProteinModelPortaliP31025
SMRiP31025
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi110125, 23 interactors
IntActiP31025, 6 interactors
STRINGi9606.ENSP00000263598

Chemistry databases

SwissLipidsiSLP:000001525

Protein family/group databases

Allergomei3990 Hom s TL

PTM databases

iPTMnetiP31025
PhosphoSitePlusiP31025

Polymorphism and mutation databases

BioMutaiLCN1
DMDMi401346

2D gel databases

UCD-2DPAGEiP31025

Proteomic databases

EPDiP31025
MaxQBiP31025
PaxDbiP31025
PeptideAtlasiP31025
PRIDEiP31025
ProteomicsDBi54757
TopDownProteomicsiP31025

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000263598; ENSP00000263598; ENSG00000160349
ENST00000371781; ENSP00000360846; ENSG00000160349
GeneIDi3933
KEGGihsa:3933
UCSCiuc004cfz.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3933
DisGeNETi3933
EuPathDBiHostDB:ENSG00000160349.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
LCN1
HGNCiHGNC:6525 LCN1
MIMi151675 gene
neXtProtiNX_P31025
OpenTargetsiENSG00000160349
PharmGKBiPA30308

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410J1KM Eukaryota
ENOG4111BH9 LUCA
GeneTreeiENSGT00440000033563
HOGENOMiHOG000231562
HOVERGENiHBG101411
InParanoidiP31025
OMAiSGKWYLK
OrthoDBiEOG091G0PIH
PhylomeDBiP31025
TreeFamiTF338197

Enzyme and pathway databases

ReactomeiR-HSA-804914 Transport of fatty acids

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
LCN1 human
EvolutionaryTraceiP31025

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
LCN1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
3933

Protein Ontology

More...
PROi
PR:P31025

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000160349 Expressed in 57 organ(s), highest expression level in tongue
CleanExiHS_LCN1
ExpressionAtlasiP31025 baseline and differential
GenevisibleiP31025 HS

Family and domain databases

Gene3Di2.40.128.20, 1 hit
InterProiView protein in InterPro
IPR012674 Calycin
IPR002345 Lipocalin
IPR000566 Lipocln_cytosolic_FA-bd_dom
IPR002450 von_Ebner_gland
PANTHERiPTHR11430 PTHR11430, 1 hit
PfamiView protein in Pfam
PF00061 Lipocalin, 1 hit
PRINTSiPR01175 VNEBNERGLAND
SUPFAMiSSF50814 SSF50814, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLCN1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P31025
Secondary accession number(s): Q5T8A1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: December 5, 2018
This is version 182 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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